Zobrazeno 1 - 10
of 13
pro vyhledávání: '"Tom Brew"'
Autor:
Pardeep Kaurah, Magali Svrcek, Toshikazu Ushijima, James Whitworth, Yasmin Nouri, Kirsty L. Harris, Emily Schulpen, Jeremy L. Davis, Lynn DeGregorio, Hidetaka Yamada, Richard H. Hardwick, Tanis D Godwin, Julie Arnold, Carla Oliveira, Jolanda M. van Dieren, Helen L. Fisher, Bostjan Humar, Katharine Nichole Holm, Han Kwang Yang, Parry Guilford, Joana Figueiredo, Fátima Carneiro, Sonia S. Kupfer, Daniel G. Coit, Paul F. Mansfield, Andrew Latchford, Ana Sofia Ribeiro, Rebecca C. Fitzgerald, Anthony E. Reeve, Nicola Bougen-Zhukov, Patrick R. Benusiglio, Enrique Norero, Kimberley Gamet, Erin Gardner, Andrew A. Sporle, Patrícia Carneiro, Joao Sanches, Johanna L. D'Addario, Marc Tischkowitz, Maybelle McLeod, Tom Brew, Elizabeth C. Monroe, Alex Boussioutas, Rachel S. van der Post, Nicoline Hoogerbrugge, Mark D. Muller, Simone Busija, Haruhiko Sugimura, Irene Gullo, Tanya M. Bisseling, Karyn Paringatai, Liying Zhang, Joana Paredes, Raquel Seruca, David G. Huntsman, Karen E Chelcun Schreiber, James M. Ford, Jeremy Rossaak, Vanessa Blair, Amanda Charlton, Susan Parry, Takeshi Nakajima, Massimiliano di Pietro, C. J. Lintott, Adrian Claydon, Annemieke Cats
Publikováno v:
Lancet Oncology, 21, 8, pp. e386-e397
Lancet Oncol
Lancet Oncology, 21, e386-e397
Lancet Oncol
Lancet Oncology, 21, e386-e397
Contains fulltext : 225261.pdf (Publisher’s version ) (Closed access) Hereditary diffuse gastric cancer (HDGC) is an autosomal dominant cancer syndrome that is characterised by a high prevalence of diffuse gastric cancer and lobular breast cancer.
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::e170c9ddf442b6b43660788219059b7b
https://hdl.handle.net/2066/225261
https://hdl.handle.net/2066/225261
Autor:
Lyvianne Decourtye-Espiard, Nicola Bougen-Zhukov, Tanis Godwin, Tom Brew, Emily Schulpen, Michael A. Black, Parry Guilford
Publikováno v:
Cancers; Volume 14; Issue 1; Pages: 175
Cancers, Vol 14, Iss 175, p 175 (2022)
Cancers
Cancers, Vol 14, Iss 175, p 175 (2022)
Cancers
Simple Summary Inactivating mutations in the CDH1 gene cause the cancer syndrome hereditary diffuse gastric cancer and are also frequent in sporadic diffuse gastric and lobular breast cancers. This research aimed to test whether cancers with CDH1 mut
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::7ae8f9f69ac3a832bda9f8cef913d321
Autor:
Tom Brew, Nicola Bougen-Zhukov, Wilson Mitchell, Lyvianne Decourtye, Emily Schulpen, Yasmin Nouri, Tanis Godwin, Parry Guilford
Publikováno v:
Cancers
Cancers, Vol 14, Iss 102, p 102 (2022)
Cancers; Volume 14; Issue 1; Pages: 102
Cancers, Vol 14, Iss 102, p 102 (2022)
Cancers; Volume 14; Issue 1; Pages: 102
Simple Summary Germline loss of the CDH1 gene is the primary genetic basis for hereditary diffuse gastric cancer, a disease resulting in elevated risk of both diffuse gastric cancer and lobular breast cancer. Current preventative treatment consists o
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::adf3aae35a6c242bed732cff985bce2a
https://pubmed.ncbi.nlm.nih.gov/35008266
https://pubmed.ncbi.nlm.nih.gov/35008266
Autor:
Kieran R Campbell, Monica Ta, Germain Ho, Tom Brew, Christine Chow, Dawn R. Cochrane, David G. Huntsman, David F. Schaeffer, Howard John Lim, Minh Bui, Parry Guilford, Steve E. Kalloger, Simon Cheung, David Farnell, Amal El-Naggar, Katherine Dixon, Pardeep Kaurah, Tanis D Godwin, J Maxwell Douglas
Publikováno v:
The Journal of pathologyReferences. 254(3)
Hereditary diffuse gastric cancer (HDGC) is a cancer syndrome caused by germline variants in CDH1, the gene encoding the cell-cell adhesion molecule E-cadherin. Loss of E-cadherin in cancer is associated with cellular dedifferentiation and poor progn
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::b65dd2542ac96b0274d86b6d3e769545
https://pubmed.ncbi.nlm.nih.gov/33797756
https://pubmed.ncbi.nlm.nih.gov/33797756
Autor:
Bryony J. Telford, Michael A. Black, Lawrence Harris, Andrew Single, S. Thomas Kelly, Gary B. Evans, Nicola Bougen-Zhukov, Parry Guilford, Henry Beetham, Sophie K. Currie, Tom Brew, Cassie E. Stylianou, Tanis D Godwin, Augustine Chen
Publikováno v:
Gastric Cancer
Background The E-cadherin gene (CDH1) is frequently mutated in diffuse gastric cancer and lobular breast cancer, and germline mutations predispose to the cancer syndrome Hereditary Diffuse Gastric Cancer. We are taking a synthetic lethal approach to
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::578193012a82272e830a0ffda15b83fa
http://europepmc.org/articles/PMC6394693
http://europepmc.org/articles/PMC6394693
Autor:
Christopher Hakkaart, Megan Taylor, Tanis D Godwin, Andrew Single, Tom Brew, Parry Guilford, Elizabeth Permina, Michael A. Black, Augustine Chen, Yasmin Nouri, Nicola Bougen-Zhukov
Publikováno v:
Cancers
Cancers, Vol 11, Iss 9, p 1359 (2019)
Volume 11
Issue 9
Cancers, Vol 11, Iss 9, p 1359 (2019)
Volume 11
Issue 9
The CDH1 gene, encoding the cell adhesion protein E-cadherin, is one of the most frequently mutated genes in gastric cancer and inactivating germline CDH1 mutations are responsible for hereditary diffuse gastric cancer syndrome (HDGC). Using cell via
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::8ccd15738194ea5d4753bad0f018c589
https://pubmed.ncbi.nlm.nih.gov/31540244
https://pubmed.ncbi.nlm.nih.gov/31540244
Autor:
Anne Marie Thow, Tom Brewer, Erica Reeve, Amerita Ravuvu, Ellen Johnson, Selai Nasiga, Sarah Mounsey
Publikováno v:
BMJ Global Health, Vol 8, Iss Suppl 8 (2023)
Externí odkaz:
https://doaj.org/article/22029daef1fe499b8fb492d73677d45a
Autor:
Anne Marie Thow, Amerita Ravuvu, Siope Vakataki Ofa, Neil Andrew, Erica Reeve, Jillian Tutuo, Tom Brewer
Publikováno v:
Globalization and Health, Vol 18, Iss 1, Pp 1-15 (2022)
Abstract Background There is growing attention to intra-regional trade in food. However, the relationship between such trade and food and nutrition is understudied. In this paper, we present an analysis of intra-regional food trade in the Pacific reg
Externí odkaz:
https://doaj.org/article/59d14fa1fd6446f090690b511028f407
Autor:
Andrew Single, Bryony J. Telford, Parry Guilford, Tom Brew, Henry Beetham, Augustine Chen, Kaylene J. Simpson, James Frick, Tanis D Godwin, Cathryn M. Gould
Publikováno v:
Molecular cancer therapeutics. 14(5)
The CDH1 gene, which encodes the cell-to-cell adhesion protein E-cadherin, is frequently mutated in lobular breast cancer (LBC) and diffuse gastric cancer (DGC). However, because E-cadherin is a tumor suppressor protein and lost from the cancer cell,
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::906d340085e1c63e33ac3da9717b6be7
https://pubmed.ncbi.nlm.nih.gov/25777964
https://pubmed.ncbi.nlm.nih.gov/25777964
Publikováno v:
Frontiers in Public Health, Vol 8 (2020)
Countries around the world are in a state of lockdown to help limit the spread of SARS-CoV-2. However, as the number of new daily confirmed cases begins to decrease, governments must decide how to release their populations from quarantine as efficien
Externí odkaz:
https://doaj.org/article/396ba68bfd024b4ba7a635779635bbc2