Are there two different binding sites for ATP on the myosin head, or only one that switches between two conformers?

Autor: Tom Barman, Corinne Lionne, Chiara Tesi

Publikováno v: Journal of Muscle Research and Cell Motility
Journal of Muscle Research and Cell Motility, Springer Verlag, 2017, 38 (2), pp.137-142. ⟨10.1007/s10974-017-9480-x⟩
Journal of Muscle Research and Cell Motility, 2017, 38 (2), pp.137-142. ⟨10.1007/s10974-017-9480-x⟩

International audience

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::300458aed39731dca1542963b59b76ea
https://hal.archives-ouvertes.fr/hal-02322680

Direct Kinetic Evidence That Lysine 215 Is Involved in the Phospho-Transfer Step of Human 3-Phosphoglycerate Kinase

Autor: Tom Barman, Perrine Lallemand, Nancy Adamek, Christian Valentin, Andrea Varga, Laurent Chaloin, Mária Vas, Judit Szabó, Corinne Lionne

Publikováno v: Biochemistry
Biochemistry, American Chemical Society, 2009, 48 (29), pp.6998-7008. ⟨10.1021/bi900396h⟩

International audience; 3-Phosphoglycerate kinase (PGK) is a promising candidate for the activation of nucleotide analogues used in antiviral and anticancer therapies. PGK is a key enzyme in glycolysis; it catalyzes the reversible reaction 1,3-bispho

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::2ec559c1f6b7422d696aa51ae2fd3a94
https://doi.org/10.1021/bi900396h

Interaction of human 3-phosphoglycerate kinase with l-ADP, the mirror image of d-ADP

Autor: Beáta Flachner, Tom Barman, Christian Périgaud, Andrea Varga, Béatrice Roy, Judit Szabó, Corinne Lionne, Peter V. Konarev, Mária Vas, Péter Závodszky, Dmitri I. Svergun

Publikováno v: Biochemical and Biophysical Research Communications
Biochemical and Biophysical Research Communications, Elsevier, 2008, 366 (4), pp.994-1000. ⟨10.1016/j.bbrc.2007.12.061⟩

International audience; l-Nucleoside-analogues, mirror images of the natural d-nucleosides, are a new class of antiviral and anticancer agents. In the cell they have to be phosphorylated to pharmacologically active triphosphate forms, the last step s

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::71677d849278452e68c0b53bc53185a3
https://doi.org/10.1016/j.bbrc.2007.12.061

Evidence that Phosphate Release Is the Rate-Limiting Step on the Overall ATPase of Psoas Myofibrils Prevented from Shortening by Chemical Cross-Linking

Autor: Tom Barman, Franck Travers, Alexandra Belus, Bogdan I. Iorga, Corinne Lionne, Nicoletta Piroddi, Robin Candau, Martin R. Webb

Publikováno v: Biochemistry. 41:13297-13308

It has been suggested that the mechanical condition determines the rate-limiting step of the ATPase of the myosin heads in fibers: when fibers are isometrically contracting, the ADP release kinetics are rate-limiting, but as the strain is reduced and

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::9194b8711c1d2f35ba7d86ee47cfbfb0
https://doi.org/10.1021/bi0260278

ATPase and Shortening Rates in Frog Fast Skeletal Myofibrils by Time-Resolved Measurements of Protein-Bound and Free Pi

Autor: Robert Stehle, Corrado Poggesi, Martin Brune, Nicoletta Piroddi, Franck Travers, Corinne Lionne, Tom Barman, Martin R. Webb, Chiara Tesi

Publikováno v: Biophysical Journal. 74:3120-3130

Shortening and ATPase rates were measured in Ca2+-activated myofibrils from frog fast muscles in unloaded conditions at 4 degrees C. ATPase rates were determined using the phosphate-binding protein method (free phosphate) and quench flow (total phosp

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::06d559a23ae1560dd4fb9cda82f83ba2
https://doi.org/10.1016/s0006-3495(98)78018-x