Zobrazeno 1 - 10
of 206
pro vyhledávání: '"Tom Böhling"'
Autor:
Kirsi Toivanen, Sami Kilpinen, Kalle Ojala, Nanna Merikoski, Sami Salmikangas, Mika Sampo, Tom Böhling, Harri Sihto
Publikováno v:
Cancers, Vol 15, Iss 22, p 5308 (2023)
Liposarcomas (LPSs) are a heterogeneous group of malignancies that arise from adipose tissue. Although LPSs are among the most common soft-tissue sarcoma subtypes, precision medicine treatments are not currently available. To discover LPS-subtype-spe
Externí odkaz:
https://doaj.org/article/47d09fa7b5ea422e8ea7ce311d12a6b0
Publikováno v:
Scientific Reports, Vol 12, Iss 1, Pp 1-8 (2022)
Abstract Eccrine porocarcinoma (EPC) is a rare malignant adnexal tumour of the skin. Part of EPCs develop from their benign counterpart, poroma (EP), with chronic light exposure and immunosuppression hypothesized to play a role in the malignant trans
Externí odkaz:
https://doaj.org/article/99dd7dc725934cc18ee3063005cac510
Autor:
Marko Salmikangas, Maria Laaksonen, Henrik Edgren, Marco Salgado, Anu Suoranta, Pirkko Mattila, Virve Koljonen, Tom Böhling, Harri Sihto
Publikováno v:
PLoS ONE, Vol 18, Iss 5, p e0285524 (2023)
Merkel cell carcinoma (MCC) is a rare cutaneous neuroendocrine carcinoma that is frequently divided into Merkel cell polyomavirus negative and positive tumors due their distinct genomic and transcriptomic profiles, and disease outcomes. Although some
Externí odkaz:
https://doaj.org/article/b73c83bccbc64b178f32e9e4e9d24760
Autor:
Klaus W Fagerstedt, Tom Böhling, Harri Sihto, Tarja Salonen, Fang Zhao, Mia Kero, Leif C Andersson, Johanna Arola
Publikováno v:
Endocrine Connections, Vol 10, Iss 9, Pp 1055-1064 (2021)
Mixed neuroendocrine-non-neuroendocrine neoplasms (MINEN) are rare tumors that consist of at least 30% of both neuroendocrine and non-neuroendocrine components. The data concerning the pathogenesis of MINEN suggest a monoclonal origin. We describe a
Externí odkaz:
https://doaj.org/article/baa7f4ad70af4838bd6c0143f8f71647
Publikováno v:
Cancers, Vol 14, Iss 15, p 3591 (2022)
Background: Merkel cell carcinoma (MCC) is a rare but highly aggressive neuroendocrine carcinoma of the skin with a poor prognosis. Improving the prognosis of MCC by means of targeted therapies requires further understanding of the mechanisms that dr
Externí odkaz:
https://doaj.org/article/0403cbbb39c247bf8c51d9f1bb5ae5be
Autor:
Eeva Kettunen, Sauli Savukoski, Kaisa Salmenkivi, Tom Böhling, Esa Vanhala, Eeva Kuosma, Sisko Anttila, Henrik Wolff
Publikováno v:
BMC Cancer, Vol 19, Iss 1, Pp 1-10 (2019)
Abstract Background Deletion of the CDKN2A locus is centrally involved in the development of several malignancies. In malignant pleural mesothelioma (MPM), it is one of the most frequently reported genomic alteration. MPM is strongly associated with
Externí odkaz:
https://doaj.org/article/131cca9545364481bce20e538437397f
Autor:
Sami Salmikangas, Tom Böhling, Nanna Merikoski, Joanna Jagdeo, Mika Sampo, Tiina Vesterinen, Harri Sihto
Publikováno v:
Cancers, Vol 14, Iss 13, p 3212 (2022)
GIST is a rare soft tissue sarcoma, for which KIT and DOG1 are used as highly sensitive diagnostic markers. Other diagnostic markers include CD34, protein kinase C θ, deficiency of succinate dehydrogenase complex subunit B, carbonic anhydrase II, an
Externí odkaz:
https://doaj.org/article/ab6799869db1459e901c3c6e7173ada1
Publikováno v:
PLoS ONE, Vol 16, Iss 5, p e0252099 (2021)
Merkel cell carcinoma (MCC) is a rare skin cancer with only limited therapeutic options for advanced disease. We previously showed that oncogene ALK is frequently expressed at the RNA level in MCC and further that ALK positivity by immunohistochemist
Externí odkaz:
https://doaj.org/article/1ba0b773467f4185a9e5fb91ca628588
Publikováno v:
Acta Dermato-Venereologica, Vol 101, Iss 1, p adv00363 (2021)
Malignant eccrine porocarcinoma is a rare skin adnexal cancer arising from the sweat glands. Little is known about the epidemiology and incidence of eccrine porocarcinoma. This registry-based study examined the epidemiology and incidence data for ecc
Externí odkaz:
https://doaj.org/article/866ba9e184b8421095eadb1bd5c6aab9
Publikováno v:
Tumor Biology, Vol 40 (2018)
Myxoinflammatory fibroblastic sarcoma is a soft-tissue neoplasm most frequently found in the distal extremities of middle-aged adults. Most myxoinflammatory fibroblastic sarcoma are low-grade tumors with propensity for local recurrence after incomple
Externí odkaz:
https://doaj.org/article/1e1ff3433e4343cca40dcbdc2b173890