Zobrazeno 1 - 10
of 41
pro vyhledávání: '"Tom B, Davidson"'
Autor:
Katrina O’Halloran, Ashley Margol, Tom B. Davidson, Dolores Estrine, Benita Tamrazi, Jennifer A. Cotter, Jianling Ji, Jaclyn A. Biegel
Publikováno v:
International Journal of Molecular Sciences, Vol 25, Iss 9, p 4882 (2024)
Medulloblastoma is the most common malignant brain tumor in childhood. Initial treatment generally includes surgery, irradiation, and chemotherapy. Approximately 20–30% of patients will experience a recurrence, which portends a very poor prognosis.
Externí odkaz:
https://doaj.org/article/254b7fe3518247e6ab2d43f789711006
Autor:
Jessica B. Foster, Marta M. Alonso, Elias Sayour, Tom B. Davidson, Mika L. Persson, Matthew D. Dun, Cassie Kline, Sabine Mueller, Nicholas A. Vitanza, Jasper van der Lugt
Publikováno v:
Neoplasia: An International Journal for Oncology Research, Vol 42, Iss , Pp 100909- (2023)
While immunotherapy for pediatric cancer has made great strides in recent decades, including the FDA approval of agents such as dinutuximab and tisgenlecleucel, these successes have rarely impacted children with pediatric central nervous system (CNS)
Externí odkaz:
https://doaj.org/article/83a724b0107446558a0c82a6d7c6ddff
Autor:
Robert M. Prins, Linda M. Liau, Gang Li, Tom B. Davidson, William H. Yong, Harlan S. Robins, Catherine Sanders, Erik Yusko, Ryan Emerson, Lin Du, Alexander M. Tucker, Richard G. Everson, Joseph P. Antonios, Tina Wang, Shaina Sedighim, Melody S. Hsu
Supplementary Figure 3 has the top 25 TCR clones from tumor biopsies at pre-treatment and the frequency of these clones in the blood.
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::71c18fe80294a41068f598ac3de4c535
https://doi.org/10.1158/2326-6066.22537174
https://doi.org/10.1158/2326-6066.22537174
Autor:
Robert M. Prins, Linda M. Liau, Gang Li, Tom B. Davidson, William H. Yong, Harlan S. Robins, Catherine Sanders, Erik Yusko, Ryan Emerson, Lin Du, Alexander M. Tucker, Richard G. Everson, Joseph P. Antonios, Tina Wang, Shaina Sedighim, Melody S. Hsu
TCR Sequencing data of each patient
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::79abfce2f88eeea18e646e09000f4ee2
https://doi.org/10.1158/2326-6066.22537168
https://doi.org/10.1158/2326-6066.22537168
Autor:
Robert M. Prins, Linda M. Liau, Gang Li, Tom B. Davidson, William H. Yong, Harlan S. Robins, Catherine Sanders, Erik Yusko, Ryan Emerson, Lin Du, Alexander M. Tucker, Richard G. Everson, Joseph P. Antonios, Tina Wang, Shaina Sedighim, Melody S. Hsu
Although immunotherapeutic strategies are emerging as adjunctive treatments for cancer, sensitive methods of monitoring the immune response after treatment remain to be established. We used a novel next-generation sequencing approach to determine whe
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::4d340ee0c411c9f1e45b4807e38597f8
https://doi.org/10.1158/2326-6066.c.6548338.v1
https://doi.org/10.1158/2326-6066.c.6548338.v1
Autor:
Robert M. Prins, Linda M. Liau, Gang Li, Tom B. Davidson, William H. Yong, Harlan S. Robins, Catherine Sanders, Erik Yusko, Ryan Emerson, Lin Du, Alexander M. Tucker, Richard G. Everson, Joseph P. Antonios, Tina Wang, Shaina Sedighim, Melody S. Hsu
Clinical patient characteristics
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::569fa38d3b79fff826cba70afcd2ef66
https://doi.org/10.1158/2326-6066.22537171.v1
https://doi.org/10.1158/2326-6066.22537171.v1
Autor:
Robert M. Prins, Linda M. Liau, Gang Li, Tom B. Davidson, William H. Yong, Harlan S. Robins, Catherine Sanders, Erik Yusko, Ryan Emerson, Lin Du, Alexander M. Tucker, Richard G. Everson, Joseph P. Antonios, Tina Wang, Shaina Sedighim, Melody S. Hsu
Cox Proportional Hazard table of the Estimated TIL content and patient survival
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::5c6056b63fb0d374c30fa73086e1d424
https://doi.org/10.1158/2326-6066.22537165.v1
https://doi.org/10.1158/2326-6066.22537165.v1
Autor:
Robert M. Prins, Linda M. Liau, Gang Li, Tom B. Davidson, William H. Yong, Harlan S. Robins, Catherine Sanders, Erik Yusko, Ryan Emerson, Lin Du, Alexander M. Tucker, Richard G. Everson, Joseph P. Antonios, Tina Wang, Shaina Sedighim, Melody S. Hsu
Supplementary Figure 1 shows representative IHC staining of TIL to confirm that these T cells are found in the parenchyma of the tumor and not tumor blood vessels.
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::d1cba61a01b9ca9f333269a4b74c85b3
https://doi.org/10.1158/2326-6066.22537180.v1
https://doi.org/10.1158/2326-6066.22537180.v1
Autor:
Shahab Asgharazadeh, Richard Sposto, Marcel Kool, Stefan M. Pfister, David T.W. Jones, Alexander R. Judkins, Mark D. Krieger, Ashley S. Margol, Gregory M. Shackleford, Jemily Malvar, Lingyun Ji, Floyd H. Gilles, Mathew Schur, Tom B. Davidson, Jingying Xu, Hong Zhou, Xiuhai Ren, Nathan Robison, Anat Erdreich-Epstein
PDF file 92K, Supplemental Fig 5: Expression of PID1 protein in human brain tumors and cell lines
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::d82bea2b8c767c454086e43a6cb428cd
https://doi.org/10.1158/1078-0432.22449965
https://doi.org/10.1158/1078-0432.22449965
Autor:
Shahab Asgharazadeh, Richard Sposto, Marcel Kool, Stefan M. Pfister, David T.W. Jones, Alexander R. Judkins, Mark D. Krieger, Ashley S. Margol, Gregory M. Shackleford, Jemily Malvar, Lingyun Ji, Floyd H. Gilles, Mathew Schur, Tom B. Davidson, Jingying Xu, Hong Zhou, Xiuhai Ren, Nathan Robison, Anat Erdreich-Epstein
PDF file - 190K, Supplemental Fig 2: Proneural and Neural GBMs have higher PID1 mRNA; higher PID1 mRNA correlates with higher OS in patients with gliomas.
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::4fc273645c3c2cb62aa3119bfff91078
https://doi.org/10.1158/1078-0432.22449974.v1
https://doi.org/10.1158/1078-0432.22449974.v1