Lessons learned after three years of SPIDER operation and the first MITICA integrated tests

Autor: Marcuzzi, D., Toigo, V., Boldrin, M., Chitarin, G., Bello, S. Dal, Grando, L., Luchetta, A., Pasqualotto, R., Pavei, M., Serianni, G., Zanotto, L., Agnello, R., Agostinetti, P., Agostini, M., Aprile, D., Barbisan, M., Battistella, M., Berton, G., Bigi, M., Brombin, M., Candela, V., Candeloro, V., Canton, A., Casagrande, R., Cavallini, C., Cavazzana, R., Cordaro, L., Cruz, N., Palma, M. Dalla, Dan, M., De Lorenzi, A., Delogu, R., De Muri, M., De Nardi, M., Denizeau, S., Fadone, M., Fellin, F., Ferro, A., Gaio, E., Gasparrini, C., Gnesotto, F., Jain, P., La Rosa, A., Lopez-Bruna, D., Lorenzini, R., Maistrello, A., Manduchi, G., Manfrin, S., Marconato, N., Mario, I., Martini, G., Milazzo, R., Patton, T., Peruzzo, S., Pilan, N., Pimazzoni, A., Poggi, C., Pomaro, N., Pouradier-Duteil, B., Recchia, M., Rigoni-Garola, A., Rizzetto, D., Rizzolo, A., Santoro, F., Sartori, E., Segalini, B., Shepherd, A., Siragusa, M., Sonato, P., Sottocornola, A., Spada, E., Spagnolo, S., Spolaore, M., Taliercio, C., Tinti, P., Tomsič, P., Trevisan, L., Ugoletti, M., Valente, M., Valisa, M., Veronese, F., Vignando, M., Zaccaria, P., Zagorski, R., Zaniol, B., Zaupa, M., Zuin, M., Cavenago, M., Boilson, D., Rotti, C., Decamps, H., Geli, F., Sharma, A., Veltri, P., Zacks, J., Simon, M., Paolucci, F., Garbuglia, A., Gutierrez, D., Masiello, A., Mico, G., Labate, C., Readman, P., Bragulat, E., Bailly-Maitre, L., Gomez, G., Kouzmenko, G., Albajar, F., Kashiwagi, M., Tobari, H., Kojima, A., Murayama, M., Hatakeyama, S., Oshita, E., Maejima, T., Shibata, N., Yamashita, Y., Watanabe, K., Singh, N. P., Singh, M. J., Dhola, H., Fantz, U., Heinemann, B., Wimmer, C., Wünderlich, D., Tsumori, K., Croci, G., Gorini, G., Muraro, A., Rebai, M., Tardocchi, M., Giacomelli, L., Rigamonti, D., Taccogna, F., Bruno, D., Rutigliano, M., Longo, S., Deambrosis, S., Miorin, E., Montagner, F., Tonti, A., Panin, F.

Publikováno v: Fusion Engineering and Design 191 (2023) 113590

ITER envisages the use of two heating neutral beam injectors plus an optional one as part of the auxiliary heating and current drive system. The 16.5 MW expected neutral beam power per injector is several notches higher than worldwide existing facili

Externí odkaz: http://arxiv.org/abs/2304.01692

Uncontrolled Donation Potential After Circulatory Death in Slovenia Could Lead to More Organ Donations: Extrapolation of SiOHCA Study Data

Autor: Domen Kulovec MD, Luka Petravić MD, Rok Miklič, Evgenija Burger BSc, Urša Keše BSc, Eva Poljanšek MD, Gašper Tomšič MSc, Tilen Pintarič AAS, Miguel Faria Lopes BSc, Ema Turnšek MSc, Andrej Gadžijev MD, Matej Strnad MD, PhD

Publikováno v: Inquiry: The Journal of Health Care Organization, Provision, and Financing, Vol 61 (2024)

Out-of-hospital cardiac arrest is one of the major health challenges faced by developed countries. Donation after circulatory death is a process of retrieving organs from individuals whose death has been confirmed by circulatory or respiratory criter

Externí odkaz: https://doaj.org/article/5c86b270114d46979160e70df5ca3d63

Minimum Quench Energy Of Nb$_3$Sn Wires With High Specific Heat Tape

Autor: Barzi, E., Novitsky, I., Turrioni, D., Zlobin, A. V., Peng, X., Tomsic, M.

A major problem of state-of-the-art Nb$_3$Sn accelerator magnets is their long training due to thermo-mechanical perturbations. Increasing the specific heat, $C_p$, of the Rutherford cable would reduce and/or eliminate training by limiting the coils

Externí odkaz: http://arxiv.org/abs/2204.05378

Molecular maps of synovial cells in inflammatory arthritis using an optimized synovial tissue dissociation protocol

Autor: Sam G. Edalat, Reto Gerber, Miranda Houtman, Janine Lückgen, Rui Lourenço Teixeira, Maria del Pilar Palacios Cisneros, Tamara Pfanner, Tadeja Kuret, Nadja Ižanc, Raphael Micheroli, Joaquim Polido-Pereira, Fernando Saraiva, Swathi Lingam, Kristina Burki, Blaž Burja, Chantal Pauli, Žiga Rotar, Matija Tomšič, Saša Čučnik, João Eurico Fonseca, Oliver Distler, Ângelo Calado, Vasco C. Romão, Caroline Ospelt, Snežna Sodin-Semrl, Mark D. Robinson, Mojca Frank Bertoncelj

Publikováno v: iScience, Vol 27, Iss 6, Pp 109707- (2024)

Summary: In this study, we optimized the dissociation of synovial tissue biopsies for single-cell omics studies and created a single-cell atlas of human synovium in inflammatory arthritis. The optimized protocol allowed consistent isolation of highly

Externí odkaz: https://doaj.org/article/4949afb345a94708b58cea17f6bb5dbc

The histone acetyl transferases CBP and p300 regulate stress response pathways in synovial fibroblasts at transcriptional and functional levels

Autor: Monika Krošel, Marcel Gabathuler, Larissa Moser, Malgorzata Maciukiewicz, Thomas Züllig, Tanja Seifritz, Matija Tomšič, Oliver Distler, Caroline Ospelt, Kerstin Klein

Publikováno v: Scientific Reports, Vol 13, Iss 1, Pp 1-10 (2023)

Abstract The activation of stress response pathways in synovial fibroblasts (SF) is a hallmark of rheumatoid arthritis (RA). CBP and p300 are two highly homologous histone acetyl transferases and writers of activating histone 3 lysine 27 acetylation

Externí odkaz: https://doaj.org/article/716a13f9744b40f683866bb8199dc2ba