Zobrazeno 1 - 10
of 274
pro vyhledávání: '"Tomás Tejero"'
Autor:
Ismael Compañón, Collin J. Ballard, Erandi Lira-Navarrete, Tanausú Santos, Serena Monaco, Juan C. Muñoz-García, Ignacio Delso, Jesus Angulo, Thomas A. Gerken, Katrine T. Schjoldager, Henrik Clausen, Tomás Tejero, Pedro Merino, Francisco Corzana, Ramon Hurtado-Guerrero, Mattia Ghirardello
Publikováno v:
JACS Au, Vol 4, Iss 9, Pp 3649-3656 (2024)
Externí odkaz:
https://doaj.org/article/ac3144beb28a4bf9854ce4dd4a027fb1
Publikováno v:
Beilstein Journal of Organic Chemistry, Vol 19, Iss 1, Pp 477-486 (2023)
The contribution to the energy barrier of a series of tethers in transannular cycloadditions of cycloalkenes with hydrazones has been computationally studied by using DFT. The Houk's distortion model has been employed to evaluate the influence of the
Externí odkaz:
https://doaj.org/article/3fcec1dd78d24d579e737e7584775486
Autor:
Manuel Pedrón, Laura Legnani, Maria-Assunta Chiacchio, Pierluigi Caramella, Tomás Tejero, Pedro Merino
Publikováno v:
Beilstein Journal of Organic Chemistry, Vol 15, Iss 1, Pp 1552-1562 (2019)
The ruthenium tetroxide-mediated oxidation of cyclopentane, tetrahydrofuran, tetrahydrothiophene and N-substituted pyrrolidines has been studied computationally by DFT and topological (analysis of the electron localization function, ELF) methods. In
Externí odkaz:
https://doaj.org/article/337ec88d7a06492b8120caa3aed7fd75
Publikováno v:
Molecules, Vol 22, Iss 8, p 1371 (2017)
The 2-Aza-Cope rearrangement of γ-alkenyl nitrones is a rare example of the neutral thermal 2-aza-Cope process that usually takes place with cationic species. During the rearrangement, a redistribution of bonds and electronic density occurs in one k
Externí odkaz:
https://doaj.org/article/2bbe65808f3e466fbb13f0ea60f73298
Autor:
Erandi Lira-Navarrete, Jessika Valero-González, Raquel Villanueva, Marta Martínez-Júlvez, Tomás Tejero, Pedro Merino, Santosh Panjikar, Ramon Hurtado-Guerrero
Publikováno v:
PLoS ONE, Vol 6, Iss 9, p e25365 (2011)
Protein O-fucosylation is an essential post-translational modification, involved in the folding of target proteins and in the role of these target proteins during embryonic development and adult tissue homeostasis, among other things. Two different e
Externí odkaz:
https://doaj.org/article/8d483ffada0347a9be9a6246c4c1ae4b
Autor:
Pilar Elías-Rodríguez, Esteban Matador, Manuel Benítez, Tomás Tejero, Elena Díez, Rosario Fernández, Pedro Merino, David Monge, José M. Lassaletta
Publikováno v:
The Journal of Organic Chemistry. 88:2487-2492
Modulable monosulfonyl squaramides have been shown to exert activation of gold(I) chloride complexes through H-bonding in an intermolecular way. Combinations of (PPh3)AuCl or IPrAuCl complexes and an optimal sulfonyl squaramide cocatalyst bearing two
Autor:
Gorka Garay, Josebe Hurtado, Manuel Pedrón, Lorena García, Efraim Reyes, Eduardo Sánchez‐Díez, Tomás Tejero, Luisa Carrillo, Pedro Merino, Jose L. Vicario
Publikováno v:
Angewandte Chemie. 135
We have demonstrated that the catalytic and enantioselective vinylcyclopropane-cyclopentene rearrangement can be carried out on (vinylcyclopropyl)acetaldehydes through activation via enamine intermediates. The reaction makes use of racemic starting m
Autor:
Francesca Clemente, Maria Giulia Davighi, Camilla Matassini, Francesca Cardona, Andrea Goti, Amelia Morrone, Paolo Paoli, Tomás Tejero, Pedro Merino, Martina Cacciarini
Publikováno v:
Clemente, F, Davighi, M G, Matassini, C, Cardona, F, Goti, A, Morrone, A, Paoli, P, Tejero, T, Merino, P & Cacciarini, M 2023, ' Light-Triggered Control of Glucocerebrosidase Inhibitors : Towards Photoswitchable Pharmacological Chaperones ', Chemistry-A European Journal, vol. 29, no. 19, e202203841 . https://doi.org/10.1002/chem.202203841
Piperidine-based photoswitchable derivatives have been developed as putative pharmacological chaperones for glucocerebrosidase (GCase), the defective enzyme in Gaucher disease (GD). The structure-activity study revealed that both the iminosugar and t
Publikováno v:
Angewandte Chemie. 134
Publikováno v:
Angewandte Chemie International Edition. 61