Zobrazeno 1 - 10
of 21
pro vyhledávání: '"Tomás Pérez-Acle"'
Autor:
Felipe Villanelo, Peter J. Minogue, Jaime Maripillán, Mauricio Reyna-Jeldes, Joaquin Jensen-Flores, Isaac E. García, Eric C. Beyer, Tomás Pérez-Acle, Viviana M. Berthoud, Agustín D. Martínez
Publikováno v:
Biological Research, Vol 57, Iss 1, Pp 1-18 (2024)
Abstract Background Members of the β-subfamily of connexins contain an intracellular pocket surrounded by amino acid residues from the four transmembrane helices. The presence of this pocket has not previously been investigated in members of the α-
Externí odkaz:
https://doaj.org/article/06defa631d704d8c9d7c419ba703475f
Autor:
Javier Campos, Francisco Osorio-Barrios, Felipe Villanelo, Sebastian E. Gutierrez-Maldonado, Pablo Vargas, Tomás Pérez-Acle, Rodrigo Pacheco
Publikováno v:
International Journal of Molecular Sciences, Vol 25, Iss 18, p 10022 (2024)
Inflammatory bowel diseases (IBDs) involve chronic inflammation of the gastrointestinal tract, where effector CD4+ T-cells play a central role. Thereby, the recruitment of T-cells into the colonic mucosa represents a key process in IBD. We recently f
Externí odkaz:
https://doaj.org/article/690392557b3f43b5ac77cb60ab884aa9
Autor:
Simón Beard, Ana Moya-Beltrán, Danitza Silva-García, Cesar Valenzuela, Tomás Pérez-Acle, Alejandra Loyola, Raquel Quatrini
Publikováno v:
Frontiers in Microbiology, Vol 14 (2023)
Mobile genetic elements (MGEs) are relevant agents in bacterial adaptation and evolutionary diversification. Stable appropriation of these DNA elements depends on host factors, among which are the nucleoid-associated proteins (NAPs). NAPs are highly
Externí odkaz:
https://doaj.org/article/8d3c342b49a94f88acbf39dfd2d065f4
Autor:
Fernando González-Nilo, Tomás Pérez-Acle, Sergio Guínez-Molinos, Daniela A Geraldo, Claudia Sandoval, Alejandro Yévenes, Leonardo S Santos, V. Felipe Laurie, Hegaly Mendoza, Raúl E Cachau
Publikováno v:
Biological Research, Vol 44, Iss 1, Pp 43-51 (2011)
After the progress made during the genomics era, bioinformatics was tasked with supporting the flow of information generated by nanobiotechnology efforts. This challenge requires adapting classical bioinformatic and computational chemistry tools to s
Externí odkaz:
https://doaj.org/article/3e7f186aeb7e401c8bd2a484c58a0200
Autor:
José M. Jiménez, J. Sebastián Contreras-Riquelme, Pía M. Vidal, Carolina Prado, Macarena Bastías, Claudio Meneses, Alberto J. M. Martín, Tomás Perez-Acle, Rodrigo Pacheco
Publikováno v:
Scientific Reports, Vol 14, Iss 1, Pp 1-12 (2024)
Abstract Inflammatory bowel diseases (IBD) are a group of chronic inflammatory conditions of the gastrointestinal tract associated with multiple pathogenic factors, including dysregulation of the immune response. Effector CD4+ T cells and regulatory
Externí odkaz:
https://doaj.org/article/d7edd9f765e241d9bccb86694fb4522d
Autor:
Álvaro, Bustos, Ignacio, Fuenzalida, Rodrigo, Santibáñez, Tomás, Pérez-Acle, Alberto J M, Martin
Publikováno v:
Methods in molecular biology (Clifton, N.J.). 1819
Complex systems are governed by dynamic processes whose underlying causal rules are difficult to unravel. However, chemical reactions, molecular interactions, and many other complex systems can be usually represented as concentrations or quantities t
Autor:
Gonzalo Hernandez, Carlos Jaime Barrios Hernandez, Gilberto Díaz, Carlos García Garino, Sergio Nesmachnow, Tomas Pérez-Acle, Mario Storti, Mariano Vázquez
This book constitutes the refereed proceedings of the First HPCLATAM - CLCAR Joint Latin American High Performance Computing Conference, CARLA 2014, held in Valparaiso, Chile, in October 2014. The 17 revised full papers and the one paper presented we
Autor:
Ana C. Abbott, Isaac E. García, Felipe Villanelo, Carolina Flores-Muñoz, Ricardo Ceriani, Jaime Maripillán, Joel Novoa-Molina, Cindel Figueroa-Cares, Tomas Pérez-Acle, Juan C. Sáez, Helmuth A. Sánchez, Agustín D. Martínez
Publikováno v:
Frontiers in Cell and Developmental Biology, Vol 10 (2023)
Some mutations in gap junction protein Connexin 26 (Cx26) lead to syndromic deafness, where hearing impairment is associated with skin disease, like in Keratitis Ichthyosis Deafness (KID) syndrome. This condition has been linked to hyperactivity of c
Externí odkaz:
https://doaj.org/article/4a2519a57af545099c4f91f689d29670
Autor:
Alvaro R. Ruiz-Fernández, Leonardo Campos, Felipe Villanelo, Jose Antonio Garate, Tomas Perez-Acle
Publikováno v:
International Journal of Molecular Sciences, Vol 24, Iss 14, p 11397 (2023)
This study takes a step in understanding the physiological implications of the nanosecond pulsed electric field (nsPEF) by integrating molecular dynamics simulations and machine learning techniques. nsPEF, a state-of-the-art technology, uses high-vol
Externí odkaz:
https://doaj.org/article/278eef394d5942d9a67ef438a0943e08
Autor:
Nibaldo C, Inestrosa, Alejandra, Alvarez, Margarita C, Dinamarca, Tomás, Pérez-Acle, Marcela, Colombres
Publikováno v:
Current Alzheimer research. 2(3)
The cholinergic system impairment observed in Alzheimer's disease (AD) patients leads to the cognitive, global and behavioral dysfunction commonly associated with dementia. The only treatment for AD has been the use of inhibitors of acetylcholinester