N-acetyl cysteine reverts the proinflammatory state induced by cigarette smoke extract in lung Calu-3 cells

Autor: Ángel G. Valdivieso, Andrea V. Dugour, Verónica Sotomayor, Mariángeles Clauzure, Juan M. Figueroa, Tomás A. Santa-Coloma

Publikováno v: Redox Biology, Vol 16, Iss , Pp 294-302 (2018)

Chronic obstructive pulmonary disease (COPD) and cystic fibrosis (CF) are lethal pulmonary diseases. Cigarette consumption is the main cause for development of COPD, while CF is produced by mutations in the CFTR gene. Although these diseases have a d

Externí odkaz: https://doaj.org/article/1e269b3b2d90436888cf218fe1e25ecf

CFTR activity and mitochondrial function

Autor: Angel Gabriel Valdivieso, Tomás A. Santa-Coloma

Publikováno v: Redox Biology, Vol 1, Iss 1, Pp 190-202 (2013)

Cystic Fibrosis (CF) is a frequent and lethal autosomal recessive disease, caused by mutations in the gene encoding the Cystic Fibrosis Transmembrane Conductance Regulator (CFTR). Before the discovery of the CFTR gene, several hypotheses attempted to

Externí odkaz: https://doaj.org/article/a8765a7277cc435b8b78d6c25f410e30

The chloride anion as a signalling effector

Autor: Ángel G. Valdivieso, Tomás A. Santa-Coloma

Publikováno v: Biological Reviews. 2019, 94(5)
Repositorio Institucional (UCA)
Pontificia Universidad Católica Argentina
instacron:UCA

Fil: Valdivieso, Ángel Gabriel. Pontificia Universidad Católica Argentina. Facultad de Ciencias Médicas. Instituto de Investigaciones Biomédicas. Laboratorio de Biología Celular y Molecular; Argentina Fil: Valdivieso, Ángel Gabriel. Consejo Nac

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::1acd0fe5c9d44377dcd48a72bf43997c
https://doi.org/10.1111/brv.12536

Epidermal growth factor receptor activity upregulates lactate dehydrogenase A expression, lactate dehydrogenase activity, and lactate secretion in cultured IB3-1 cystic fibrosis lung epithelial cells

Autor: María Macarena Massip-Copiz, Mariángeles Clauzure, Ángel G. Valdivieso, María Ángeles Aguilar, Consuelo Mori, Tomás A. Santa-Coloma, Cristian J A Asensio

Publikováno v: Postprint de artículo publicado en Biochemistry and Cell Biology. 2021, 99 (4)
CONICET Digital (CONICET)
Consejo Nacional de Investigaciones Científicas y Técnicas
instacron:CONICET
Repositorio Institucional (UCA)
Pontificia Universidad Católica Argentina
instacron:UCA

Cystic fibrosis (CF) is caused by mutations in the CFTR gene. It has been postulated that a reduced HCO3 − transport in CF through CFTR may lead to a decreased airway surface liquid (ASL) pH. In contrast, others have reported no changes in the extr

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::3452890939cbdbdba8d607be4bbd0038
https://pubmed.ncbi.nlm.nih.gov/33481676

CFTR chloride channel activity modulates the mitochondrial morphology in cultured epithelial cells

Autor: Camila Falduti, Tomás A. Santa-Coloma, Ángel G. Valdivieso, Rocío García, Raquel Jara, Mariángeles Clauzure, María M. Massip-Copiz, María Á. Aguilar

Publikováno v: International Journal of Biochemistry and Cell Biology, Vol. 135, 105976, 2021
Repositorio Institucional (UCA)
Pontificia Universidad Católica Argentina
instacron:UCA

Fil: García Solcá, Rocío. Pontificia Universidad Católica Argentina. Facultad de Ciencias Médicas. Instituto de Investigaciones Biomédicas. Laboratorio de Biología Celular y Molecular; Argentina Fil: García Solcá, Rocío. Consejo Nacional de

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::a00f741d84236988b83d64235b74cf1f
https://repositorio.uca.edu.ar/handle/123456789/14597