Zobrazeno 1 - 10 of 70 pro vyhledávání: '"Tomás A Santa-Coloma"'
1
Akademický článek
Disruption of interleukin-1β autocrine signaling rescues complex I activity and improves ROS levels in immortalized epithelial cells with impaired cystic fibrosis transmembrane conductance regulator (CFTR) function.
Autor: Mariángeles Clauzure, Angel G Valdivieso, María M Massip Copiz, Gustavo Schulman, María Luz Teiber, Tomás A Santa-Coloma
Publikováno v: PLoS ONE, Vol 9, Iss 6, p e99257 (2014)
Patients with cystic fibrosis (CF) have elevated concentration of cytokines in sputum and a general inflammatory condition. In addition, CF cells in culture produce diverse cytokines in excess, including IL-1β. We have previously shown that IL-1β,
Externí odkaz: https://doaj.org/article/e1e7b2b09f244255a6805ab93cacea8f
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2
Akademický článek
The mitochondrial complex I activity is reduced in cells with impaired cystic fibrosis transmembrane conductance regulator (CFTR) function.
Autor: Angel G Valdivieso, Mariángeles Clauzure, María C Marín, Guillermo L Taminelli, María M Massip Copiz, Francisco Sánchez, Gustavo Schulman, María L Teiber, Tomás A Santa-Coloma
Publikováno v: PLoS ONE, Vol 7, Iss 11, p e48059 (2012)
Cystic fibrosis (CF) is a frequent and lethal autosomal recessive disease. It results from different possible mutations in the CFTR gene, which encodes the CFTR chloride channel. We have previously studied the differential expression of genes in CF a
Externí odkaz: https://doaj.org/article/30c5dfba9f9f4babbffaf3c44fc5646a
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3
Overlapping synthetic peptides as a tool to map protein-protein interactions ̶FSH as a model system of nonadditive interactions
Autor: Tomás Antonio Santa Coloma
Publikováno v: Biochimica et Biophysica Acta (BBA) Vol.1886, No. 7, 2022
Repositorio Institucional (UCA)
Pontificia Universidad Católica Argentina
instacron:UCA
Fil: Santa Coloma, Tomás Antonio. Pontificia Universidad Católica Argentina. Facultad de Ciencias Médicas. Instituto de Investigaciones Biomédicas; Argentina Abstract: In earlier work, we used partially overlapped synthetic peptides as a tool to
Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::a8ce419ce76a5b8d6a47b3bbf318d52c
https://repositorio.uca.edu.ar/handle/123456789/13975
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4
The chloride anion as a signalling effector
Autor: Ángel G. Valdivieso, Tomás A. Santa-Coloma
Publikováno v: Biological Reviews. 2019, 94(5)
Repositorio Institucional (UCA)
Pontificia Universidad Católica Argentina
instacron:UCA
Fil: Valdivieso, Ángel Gabriel. Pontificia Universidad Católica Argentina. Facultad de Ciencias Médicas. Instituto de Investigaciones Biomédicas. Laboratorio de Biología Celular y Molecular; Argentina Fil: Valdivieso, Ángel Gabriel. Consejo Nac
Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::1acd0fe5c9d44377dcd48a72bf43997c
https://doi.org/10.1111/brv.12536
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5
NLR family pyrin domain containing 3 (NLRP3) and caspase 1 (CASP1) modulation by intracellular Cl
Autor: Mariángeles, Clauzure, Ángel G, Valdivieso, Andrea V, Dugour, Consuelo, Mori, María M, Massip-Copiz, María Á, Aguilar, Verónica, Sotomayor, Cristian J A, Asensio, Juan M, Figueroa, Tomás A, Santa-Coloma
Publikováno v: Immunology
The impairment of the cystic fibrosis transmembrane conductance regulator (CFTR) activity induces intracellular chloride (Cl(–)) accumulation. The anion Cl(–), acting as a second messenger, stimulates the secretion of interleukin‐1β (IL‐1β)
Externí odkaz: https://explore.openaire.eu/search/publication?articleId=pmid________::afe30d4e712b4a464e6ddc05e5cea28e
https://pubmed.ncbi.nlm.nih.gov/33835494
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6
Epidermal growth factor receptor activity upregulates lactate dehydrogenase A expression, lactate dehydrogenase activity, and lactate secretion in cultured IB3-1 cystic fibrosis lung epithelial cells
Autor: María Macarena Massip-Copiz, Mariángeles Clauzure, Ángel G. Valdivieso, María Ángeles Aguilar, Consuelo Mori, Tomás A. Santa-Coloma, Cristian J A Asensio
Publikováno v: Postprint de artículo publicado en Biochemistry and Cell Biology. 2021, 99 (4)
CONICET Digital (CONICET)
Consejo Nacional de Investigaciones Científicas y Técnicas
instacron:CONICET
Repositorio Institucional (UCA)
Pontificia Universidad Católica Argentina
instacron:UCA
Cystic fibrosis (CF) is caused by mutations in the CFTR gene. It has been postulated that a reduced HCO3 − transport in CF through CFTR may lead to a decreased airway surface liquid (ASL) pH. In contrast, others have reported no changes in the extr
Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::3452890939cbdbdba8d607be4bbd0038
https://pubmed.ncbi.nlm.nih.gov/33481676
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7
NLR family pyrin domain containing 3 (NLRP3) and caspase 1 (CASP1) modulation by intracellular Cl– concentration
Autor: María M. Massip-Copiz, Consuelo Mori, Verónica Sotomayor, Ángel G. Valdivieso, Mariángeles Clauzure, Andrea V. Dugour, María Á. Aguilar, Juan Manuel Figueroa, Tomás A. Santa-Coloma, Cristian J. A. Asensio
Publikováno v: Immunology Vol.163, No.4, 2021
Repositorio Institucional (UCA)
Pontificia Universidad Católica Argentina
instacron:UCA
Fil: Clauzure, Mariángeles. Pontificia Universidad Católica Argentina. Facultad de Ciencias Médicas. Instituto de Investigaciones Biomédicas. Laboratorio de Biología Celular y Molecular; Argentina Fil: Clauzure, Mariángeles. Consejo Nacional de
Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::df0f94cac0d0faeaf5fefa17b1be5f18
https://repositorio.uca.edu.ar/handle/123456789/14599
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8
CFTR chloride channel activity modulates the mitochondrial morphology in cultured epithelial cells
Autor: Camila Falduti, Tomás A. Santa-Coloma, Ángel G. Valdivieso, Rocío García, Raquel Jara, Mariángeles Clauzure, María M. Massip-Copiz, María Á. Aguilar
Publikováno v: International Journal of Biochemistry and Cell Biology, Vol. 135, 105976, 2021
Repositorio Institucional (UCA)
Pontificia Universidad Católica Argentina
instacron:UCA
Fil: García Solcá, Rocío. Pontificia Universidad Católica Argentina. Facultad de Ciencias Médicas. Instituto de Investigaciones Biomédicas. Laboratorio de Biología Celular y Molecular; Argentina Fil: García Solcá, Rocío. Consejo Nacional de
Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::a00f741d84236988b83d64235b74cf1f
https://repositorio.uca.edu.ar/handle/123456789/14597
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9
The Airborne and Gastrointestinal Coronavirus SARS-COV-2 Pathways
Autor: Tomás A. Santa-Coloma
Since there is not a clear consensus about the possibility for COVID-2 to be an airborne disease, exists a controversy regarding the need to use surgical masks to prevent its spread. Here, using the Kepler conjecture for ideal packaging, the number o
Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_________::7a2b0470d54c9c9601021d7de1eb55ed
https://doi.org/10.20944/preprints202004.0133.v2
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10
Concentración de Interleuquina 1-β durante la placentación porcina
Autor: Mirta Adriana Koncurat, Carolina Velez, Tomás A. Santa Coloma, Claudio Gustavo Barbeito, Delia María Williamson, Mariángeles Clauzure
Publikováno v: Ciencia Veterinaria, Vol 20, Iss 1, Pp 13-24 (2018)
SEDICI (UNLP)
Universidad Nacional de La Plata
instacron:UNLP
La IL-1β, citoquina proinflamatoria, está involucrada en la implantación del conceptus, la invasión y la inmunotolerancia feto-materna. Participa en el desarrollo del trofoblasto, comunicación con el endometrio y es necesaria para una correcta i
Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::65d570641da8a3b24c8b5e2446eb9864
https://cerac.unlpam.edu.ar/index.php/veterinaria/article/view/3536
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