Zobrazeno 1 - 10
of 20
pro vyhledávání: '"Tomáš Perečko"'
Autor:
Jana Pereckova, Silvia Martiniakova, Juraj Payer, Martin Falk, Zdenko Killinger, Tomas Perecko
Publikováno v:
EXCLI Journal : Experimental and Clinical Sciences, Vol 21, Pp 580-594 (2022)
Administration of biological therapy (BT) in rheumatoid arthritis (RA) patients is often associated with hematological complications, which result in switching among therapies. Thus, there is an instant need for suitable screening parameters that wil
Externí odkaz:
https://doaj.org/article/186326ca42464d5d93efac113a1d3a21
Autor:
Jana Pereckova, Michaela Pekarova, Nikoletta Szamecova, Zuzana Hoferova, Kristyna Kamarytova, Martin Falk, Tomas Perecko
Publikováno v:
International Journal of Molecular Sciences, Vol 22, Iss 18, p 9981 (2021)
Nitro-oleic acid (NO2-OA), pluripotent cell-signaling mediator, was recently described as a modulator of the signal transducer and activator of transcription 3 (STAT3) activity. In our study, we discovered new aspects of NO2-OA involvement in the reg
Externí odkaz:
https://doaj.org/article/b68695ed57fb42ee96c4c4ff608ed3d0
Autor:
Thomas F. M. Luxford, Stanislav A. Pshenichnyuk, Nail L. Asfandiarov, Tomáš Perečko, Martin Falk, Jaroslav Kočišek
Publikováno v:
International Journal of Molecular Sciences, Vol 21, Iss 21, p 8173 (2020)
We report experimental results of low-energy electron interactions with 5-nitro-2,4-dichloropyrimidine isolated in the gas phase and hydrated in a cluster environment. The molecule exhibits a very rare combination of many so far hypothesized low-ener
Externí odkaz:
https://doaj.org/article/17dde3baa5114f19b31028bc70c14bcf
Autor:
Jana Kudová, Jiřina Procházková, Ondřej Vašiček, Tomáš Perečko, Miroslava Sedláčková, Martin Pešl, Jiří Pacherník, Lukáš Kubala
Publikováno v:
PLoS ONE, Vol 11, Iss 6, p e0158358 (2016)
Cardiac cell formation, cardiomyogenesis, is critically dependent on oxygen availability. It is known that hypoxia, a reduced oxygen level, modulates the in vitro differentiation of pluripotent cells into cardiomyocytes via hypoxia inducible factor-1
Externí odkaz:
https://doaj.org/article/f81cf6acac094d7e80042acf4ad465ec
Autor:
Juraj Harmatha, Jana Pečivová, Katarína Drábiková, Tatiana Mačičková, Tomáš Perečko, Viera Jančinová, Rado Nosáľ
Publikováno v:
Interdisciplinary Toxicology
Interdisciplinary Toxicology, Vol 10, Iss 2, Pp 56-60 (2017)
Interdisciplinary Toxicology, Vol 10, Iss 2, Pp 56-60 (2017)
In this study we investigated the effect of five therapeutically used drugs and four natural polyphenolic compounds on the mechanism of oxidative burst of human neutrophils concerning their participation in the generation of reactive oxygen species (
Autor:
Pierre van der Bruggen, Marie Lipoldová, Sven Brandau, Anca Dorhoi, Jo A. Van Ginderachter, Tomáš Perečko, Juan F. Santibanez, Annika M. Bruger, Margarida Saraiva, Katarzyna Barczyk-Kahlert, Gunes Esendagli
Publikováno v:
Cancer Immunology, Immunotherapy : other biological response modifications, Vol. 68, no. 4, p. 631-644 (2019)
Cancer Immunology Immunotherapy
Cancer Immunology Immunotherapy
Myeloid-derived suppressor cells (MDSC) are a heterogeneous group of mononuclear and polymorphonuclear myeloid cells, which are present at very low numbers in healthy subjects, but can expand substantially under disease conditions. Depending on disea
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::85957bdf594fc73171f4bb238b9fbc7e
https://www.scopus.com/inward/record.url?partnerID=HzOxMe3b&origin=inward&scp=85047222918
https://www.scopus.com/inward/record.url?partnerID=HzOxMe3b&origin=inward&scp=85047222918
Autor:
Radomír Nosáľ, Marianna Lucová, Katarína Drábiková, Tomáš Perečko, Danica Mihalova, Katarína Bauerová, Viera Jančinová, Silvia Pažoureková
Publikováno v:
International Immunopharmacology. 28:175-181
Hydroxychloroquine is used in the therapy of rheumatoid arthritis or lupus erythematosus. Although these diseases are often accompanied by activation of neutrophils, there are still few data relating to the impact of hydroxychloroquine on these cells
Molecular pharmacology of antihistamines in inhibition of oxidative burst of professional phagocytes
Publikováno v:
General physiology and biophysics. 34:209-216
Antihistamines of the H₁and H₃/H₄groups interfere with oxidative burst of human professional phagocytes in vitro. In the concentration of 10 μM, H₁antihistamines of the 1st and 2nd generation inhibited oxidative burst of human neutrophils in
Publikováno v:
Interdisciplinary Toxicology
Prolonged or excessive formation and liberation of cytotoxic substances from neutrophils intensifies inflammation and the risk of tissue damage. From this perspective, administration of substances which are able to reduce activity of neutrophils and
Publikováno v:
Toxicology Letters. 280:S215-S216