Zobrazeno 1 - 10
of 20
pro vyhledávání: '"Tomáš Macháček"'
Publikováno v:
Parasitology, Vol 151, Pp 412-420 (2024)
The incidences of multiple sclerosis have risen worldwide, yet neither the trigger nor efficient treatment is known. Some research is dedicated to looking for treatment by parasites, mainly by helminths. However, little is known about the effect of h
Externí odkaz:
https://doaj.org/article/1831fd3501da48a58fc23723ddfcf3af
Autor:
Franziska Woitschach, Marlen Kloss, Sabine Kischkel, Tomáš Macháček, Cindy Reinholdt, Volkmar Senz, Karsten Schlodder, Micha Löbermann, Niels Grabow, Emil C. Reisinger, Martina Sombetzki
Publikováno v:
Frontiers in Bioengineering and Biotechnology, Vol 12 (2024)
Introduction: The biocompatibility of an implanted material strongly determines the subsequent host immune response. After insertion into the body, each medical device causes tissue reactions. How intense and long-lasting these are is defined by the
Externí odkaz:
https://doaj.org/article/ff06b97bde04407c93e25de3955276ed
Autor:
Manfred Schreiber, Tomáš Macháček, Vojtěch Vajs, Barbora Šmídová, Martin Majer, Jiří Hrdý, Ondřej Tolde, Jan Brábek, Daniel Rösel, Petr Horák
Publikováno v:
Frontiers in Immunology, Vol 15 (2024)
Cancer is still one of the leading causes of death, with an estimated 19.3 million new cases every year. Our paper presents the tumor-suppressing effect of Taenia crassiceps and Mesocestoides corti on B16F10 melanoma, the intraperitoneal application
Externí odkaz:
https://doaj.org/article/c0cd1e571005414dafc8ba25864b2198
Autor:
Franziska Winkelmann, Manuela Gesell Salazar, Christian Hentschker, Stephan Michalik, Tomáš Macháček, Christian Scharf, Emil C. Reisinger, Uwe Völker, Martina Sombetzki
Publikováno v:
Scientific Reports, Vol 12, Iss 1, Pp 1-10 (2022)
Abstract The tegument, as the surface layer of adult male and female Schistosoma spp. represents the protective barrier of the worms to the hostile environment of the host bloodstream. Here we present the first comparative analysis of sex-specific te
Externí odkaz:
https://doaj.org/article/ed66621b100f493c86e5994e2d4f5cb2
Autor:
Tomáš Macháček, Roman Leontovyč, Barbora Šmídová, Martin Majer, Oldřich Vondráček, Iveta Vojtěchová, Tomáš Petrásek, Petr Horák
Publikováno v:
PLoS Pathogens, Vol 18, Iss 2, p e1010302 (2022)
Helminth neuroinfections represent serious medical conditions, but the diversity of the host-parasite interplay within the nervous tissue often remains poorly understood, partially due to the lack of laboratory models. Here, we investigated the neuro
Externí odkaz:
https://doaj.org/article/47c135e664624f9c871112b938791765
Publikováno v:
Parasites & Vectors, Vol 13, Iss 1, Pp 1-14 (2020)
Abstract Background Avian schistosomes, the causative agents of human cercarial dermatitis (or swimmer’s itch), die in mammals but the mechanisms responsible for parasite elimination are unknown. Here we examined the role of reactive nitrogen speci
Externí odkaz:
https://doaj.org/article/9de474d984d64066989e91fef6c1a9f1
Autor:
Hana Dvořáková, Roman Leontovyč, Tomáš Macháček, Anthony J. O'Donoghue, Ondřej Šedo, Zbyněk Zdráhal, Charles S. Craik, Conor R. Caffrey, Petr Horák, Libor Mikeš
Publikováno v:
Frontiers in Cellular and Infection Microbiology, Vol 10 (2020)
Schistosomula (the post-infective stages) of the neurotropic schistosome Trichobilharzia regenti possess multiple isoforms of cathepsin B1 peptidase (TrCB1.1-TrCB1.6) with involvement in nutrient digestion. The comparison of substrate preferences of
Externí odkaz:
https://doaj.org/article/6a312c927f794025831e214f8b7b7f3c
Publikováno v:
Parasites & Vectors, Vol 9, Iss 1, Pp 1-10 (2016)
Abstract Background Helminth neuroinfections represent a serious health problem, but host immune mechanisms in the nervous tissue often remain undiscovered. This study aims at in vitro characterization of the response of murine astrocytes and microgl
Externí odkaz:
https://doaj.org/article/d5f8af50fd8f48d8ba67ae1133325247
Autor:
Jan Novák, Tomáš Macháček, Martin Majer, Marie Kostelanská, Kateřina Skulinová, Viktor Černý, Libuše Kolářová, Jiří Hrdý, Petr Horák
Publikováno v:
Parasitology. 149:1720-1728
Toxocara canis, a gastrointestinal parasite of canids, is also highly prevalent in many paratenic hosts, such as mice and humans. As with many other helminths, the infection is associated with immunomodulatory effects, which could affect other inflam
Publikováno v:
Parasite immunologyREFERENCES. 42(6)
Trichobilharzia regenti (Schistosomatidae) percutaneously infects birds and mammals and invades their central nervous system (CNS). Here, we characterized the peripheral immune response of infected mice and showed how it was influenced by the parasit