Zobrazeno 1 - 10
of 52
pro vyhledávání: '"Tomáš Kraus"'
Publikováno v:
Chemical Science. 14:4059-4069
New lipid-linked 2′-deoxyribonucleoside triphosphates were synthesized and used for enzymatic construction of various lipid–oligonucleotide conjugates capable of efficient anchoring to plasma membranes.
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::77259b767c7d69b75ebab6d0d34148e3
https://doi.org/10.1039/d2sc06718h
https://doi.org/10.1039/d2sc06718h
Autor:
Ambra Spampinato, Erika Kužmová, Radek Pohl, Veronika Sýkorová, Milan Vrábel, Tomáš Kraus, Michal Hocek
Publikováno v:
Bioconjugate Chemistry.
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::b5a29e51370a52e632e3e42d3250c0de
https://doi.org/10.1021/acs.bioconjchem.3c00064
https://doi.org/10.1021/acs.bioconjchem.3c00064
Publikováno v:
Bioconjugate chemistry.
Nucleosides and 2'-deoxyribonucleoside triphosphates (dNTPs) bearing 3,3'-dimethoxy-2,2'-diphenyl-6-(4-hydroxyphenyl)-bodipy fluorophore attached through a propargyl or propargyl-triethylene glycol linker to position 5 of 2'-deoxycytidine were design
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::d53d0b6d84704f164f01efcf45d99da1
https://pubmed.ncbi.nlm.nih.gov/36519639
https://pubmed.ncbi.nlm.nih.gov/36519639
Autor:
Ján Matyašovský, Radek Pohl, Pedro Güixens-Gallardo, Attila Palágyi, Michal Hocek, Miroslav Kuba, Laure Tack, Tomáš Kraus
Publikováno v:
Organic & Biomolecular Chemistry. 19:9966-9974
We designed and synthesized nucleosides bearing aminophenyl- or aminonaphthyl-3-methoxychromone fluorophores attached at position 5 of cytosine or thymine and converted them to nucleoside triphosphates. The fluorophores showed solvatochromic fluoresc
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::92a3d21433038b64fc3e21db60be7a28
https://doi.org/10.1039/d1ob02098f
https://doi.org/10.1039/d1ob02098f
Publikováno v:
Chemistry (Weinheim an Der Bergstrasse, Germany)
Thymidine triphosphate bearing benzylidene-tetrahydroxanthylium near-IR fluorophore linked to the 5-methyl group via triazole was synthesized through the CuAAC reaction and was used for polymerase synthesis of labelled DNA probes. The fluorophore lig
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::8660269531163766f52ace5146b5f066
https://doi.org/10.1002/chem.202003192
https://doi.org/10.1002/chem.202003192
Publikováno v:
Analytical Biochemistry. 614:114002
The reported method allows for a simple and rapid monitoring of DNA replication and cell cycle progression in eukaryotic cells in vitro. The DNA of replicating cells is labeled by incorporation of a metabolically-active fluorescent (Cy3) deoxyuridine
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::e70fd37c18eabc3fa218b024af7350c5
https://doi.org/10.1016/j.ab.2020.114002
https://doi.org/10.1016/j.ab.2020.114002
Publikováno v:
Chemistry – A European Journal. 26:11911-11911
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::bfd75e490de8ac47ddcb5f0bbbf99f97
https://doi.org/10.1002/chem.202003781
https://doi.org/10.1002/chem.202003781
Autor:
Michal Hocek, Radek Pohl, Ján Matyašovský, Pedro Güixens-Gallardo, Tomáš Kraus, Dmytro Dziuba, Zbigniew Zawada
Publikováno v:
Bioconjugate chemistry. 29(11)
Synthesis of cytosine, uracil, and 7-deazaadenine 2′-deoxyribonucleosides and triphosphates (dNTPs) bearing hexamethylated phenyl-bodipy fluorophore attached at position 5 of pyrimidines or at position 7 of 7-deazapurine was developed. All the titl
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::6f07c4263e16237233f4ecb5ea4436b1
https://pubmed.ncbi.nlm.nih.gov/30365300
https://pubmed.ncbi.nlm.nih.gov/30365300
Publikováno v:
Angewandte Chemie (International ed. in English). 57(31)
Chemically modified nucleoside triphosphates (NTPs) are widely exploited as unnatural metabolites in chemical biology and medicinal chemistry. Because anionic NTPs do not permeate cell membranes, their corresponding neutral precursors are employed in
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::50557d482083f697e3b1c8587db85e59
https://pubmed.ncbi.nlm.nih.gov/29578619
https://pubmed.ncbi.nlm.nih.gov/29578619