Zobrazeno 1 - 7
of 7
pro vyhledávání: '"Tomáš Koblas"'
Autor:
Lucie Kosinová, Monika Cahová, Eva Fábryová, Irena Týcová, Tomáš Koblas, Ivan Leontovyč, František Saudek, Jan Kříž
Publikováno v:
PLoS ONE, Vol 11, Iss 4, p e0152664 (2016)
The use of RT-qPCR provides a powerful tool for gene expression studies; however, the proper interpretation of the obtained data is crucially dependent on accurate normalization based on stable reference genes. Recently, strong evidence has been show
Externí odkaz:
https://doaj.org/article/094de8be66104c1e8d01e842a22810cc
Autor:
Martina, Zahradnická, Peter, Girman, Jan, Kříž, Zuzana, Berková, Tomáš, Koblas, Ema, Vávrová, Lucie, Kosinová, David, Habart, Eva, Fábryová, Eva, Dovolilová, Tomáš, Neškudla, Jan, Peregrin, Jozef, Kováč, Květoslav, Lipár, Matěj, Kočík, Lenka, Németová, Jiří, Svoboda, František, Saudek
Publikováno v:
Casopis lekaru ceskych. 155(7)
Islet transplantation (ITx) started in 2005 in IKEM as a potentially safer alternative to pancreas transplantation (PTx), which so far had represented the method of choice in type-1 diabetic patients with conservatively intractable hypoglycemia unawa
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=pmid________::3fa34907c26f87a571ea8108336f4d81
https://pubmed.ncbi.nlm.nih.gov/27990829
https://pubmed.ncbi.nlm.nih.gov/27990829
Autor:
Jiří Hudeček, Marie Stiborová, Petr Hodek, Božena Kubíčková, Helena Rýdlová, Miroslav Šulc, Tomáš Koblas
Publikováno v:
Collection of Czechoslovak Chemical Communications. 69:659-673
Using chicken antibodies IgY (purified from egg yolks) against mammalian cytochromes P450 and by means of cytochrome P450 marker substrates, we found for the first time the presence of hepatopancreatic cytochrome P450 in crayfishOrconectes limosus(an
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::5ba0a11fa17f39b4c8821c7ce70bbadf
https://doi.org/10.1135/cccc20040659
https://doi.org/10.1135/cccc20040659
Publikováno v:
Cancer letters. 220(2)
Cytochrome P450 1A1 (CYP1A1) is one of the most important enzymes implicated in the metabolic activation of carcinogens. To date, there is still conflicting evidence for the expression of enzymatically functional CYP1A1 in human liver. In the present
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::bb8435afdb2c504f63ab05e345c1c23c
https://pubmed.ncbi.nlm.nih.gov/15766589
https://pubmed.ncbi.nlm.nih.gov/15766589
Autor:
Ivan Leontovyc, David Habart, Sarka Loukotova, Lucie Kosinova, Jan Kriz, Frantisek Saudek, Tomas Koblas
Publikováno v:
PLoS ONE, Vol 12, Iss 8, p e0182497 (2017)
Cell reprogramming requires efficient delivery of reprogramming transcription factors into the cell nucleus. Here, we compared the robustness and workload of two protein delivery methods that avoid the risk of genomic integration. The first method is
Externí odkaz:
https://doaj.org/article/7de4e8ef1c0448b79250f93eb0952a14
Publikováno v:
Molecular Therapy: Nucleic Acids, Vol 5, Iss C (2016)
Direct reprogramming of pancreatic nonendocrine cells into insulin-producing β-cells represents a promising approach for the treatment of insulin-dependent diabetes. However, its clinical application is limited by the potential for insertional mutag
Externí odkaz:
https://doaj.org/article/2492d679e4c34550afc3224b28132fcf
Autor:
Zuzana Berkova, Frantisek Saudek, Peter Girman, Klara Zacharovova, Jan Kriz, Eva Fabryova, Ivan Leontovyc, Tomas Koblas, Lucie Kosinova, Tomas Neskudla, Ema Vavrova, David Habart, Sarka Loukotova, Martina Zahradnicka, Kvetoslav Lipar, Ludek Voska, Jelena Skibova
Publikováno v:
Journal of Diabetes Research, Vol 2016 (2016)
Variability of pancreatic donors may significantly impact the success of islet isolation. The aim of this study was to evaluate donor factors associated with isolation failure and to investigate whether immunohistology could contribute to organ selec
Externí odkaz:
https://doaj.org/article/a8a9785c23554c80bfd8aefe04b6a3aa