Zobrazeno 1 - 10
of 14
pro vyhledávání: '"Tomáš Ječmen"'
Publikováno v:
Cosmetics, Vol 11, Iss 2, p 33 (2024)
Cytochrome P450 (CYP) enzymes play a key role in the metabolism of foreign compounds and in the biosynthesis and catabolism of endogenous substances, including hormones. The activity of these enzymes can be affected by various xenobiotics, such as po
Externí odkaz:
https://doaj.org/article/68de8717ba484b91843d38ec5e0ca848
Autor:
Ondřej Skořepa, Samuel Pazicky, Barbora Kalousková, Jan Bláha, Celeste Abreu, Tomáš Ječmen, Michal Rosůlek, Alexander Fish, Arthur Sedivy, Karl Harlos, Jan Dohnálek, Tereza Skálová, Ondřej Vaněk
Publikováno v:
Cancers, Vol 12, Iss 7, p 1998 (2020)
NKp30 is one of the main human natural killer (NK) cell activating receptors used in directed immunotherapy. The oligomerization of the NKp30 ligand binding domain depends on the length of the C-terminal stalk region, but our structural knowledge of
Externí odkaz:
https://doaj.org/article/589181152d3f4099b33691080b4019bc
Publikováno v:
Analytical and Bioanalytical Chemistry. 413:4321-4328
Glycoproteomics is a challenging branch of proteomics because of the micro- and macro-heterogeneity of protein glycosylation. Hydrophilic interaction liquid chromatography (HILIC) is an advantageous alternative to reversed-phase chromatography for in
Glycan-specific precipitation of glycopeptides in high organic content sample solvents used in HILIC
Publikováno v:
J Chromatogr B Analyt Technol Biomed Life Sci
The composition of a sample solvent has a crucial impact on separations in hydrophilic interaction liquid chromatography (HILIC). In this short communication, we studied the effect of an organic modifier in the sample solvent on the solubility of dif
Autor:
Tomáš Ječmen, Marie Stiborová, Petr Hodek, Věra Černá, Renata Ptáčková, Miroslav Šulc, Helena Dračínská, Jiří Hudeček
Publikováno v:
Methods. 89:128-137
Protein-protein interactions play a central role in the regulation of many biochemical processes (e.g. the system participating in enzyme catalysis). Therefore, a deeper understanding of protein-protein interactions may contribute to the elucidation
Publikováno v:
International Journal of Molecular Sciences, Vol 15, Iss 6, Pp 9224-9241 (2014)
International Journal of Molecular Sciences; Volume 15; Issue 6; Pages: 9224-9241
International Journal of Molecular Sciences
International Journal of Molecular Sciences; Volume 15; Issue 6; Pages: 9224-9241
International Journal of Molecular Sciences
Protein–protein interaction was investigated using a protein nanoprobe capable of photo-initiated cross-linking in combination with high-resolution and tandem mass spectrometry. This emerging experimental approach introduces photo-analogs of amino
Autor:
Tomáš, Ječmen, Renata, Ptáčková, Daniel, Kavan, Věra, Cerná, Petr, Hodek, Marie, Stiborová, Jiří, Hudeček, Miroslav, Sulc
Publikováno v:
Neuro endocrinology letters. 35
The mammalian mixed function oxidase (MFO) system participates in hydroxylation of many hydrophobic endogenous compounds as well as xenobiotics such as drugs and carcinogens. This biotransformation system, located in a membrane of endoplasmic reticul
Autor:
Josef Komenda, Tomáš Ječmen, Roman Sobotka, Markéta Linhartová, Jiří Šetlík, Petr Halada, Lenka Bučinská
Publikováno v:
Molecular Microbiology.
Summary Type IV pilins are bacterial proteins that are small in size but have a broad range of functions, including motility, transformation competence and secretion. Although pilins vary in sequence, they possess a characteristic signal peptide that
Autor:
Markéta, Linhartová, Lenka, Bučinská, Petr, Halada, Tomáš, Ječmen, Jiří, Setlík, Josef, Komenda, Roman, Sobotka
Publikováno v:
Molecular microbiology. 93(6)
Type IV pilins are bacterial proteins that are small in size but have a broad range of functions, including motility, transformation competence and secretion. Although pilins vary in sequence, they possess a characteristic signal peptide that has to
Publikováno v:
International Journal of Molecular Sciences, Vol 24, Iss 14, p 11779 (2023)
Residue-specific incorporation of non-canonical amino acids (ncAAs) introduces bio-orthogonal functionalities into proteins. As such, this technique is applied in protein characterization and quantification. Here, we studied protein expression with t
Externí odkaz:
https://doaj.org/article/5a854b3576b04900a88198036cbe1009