Zobrazeno 1 - 8
of 8
pro vyhledávání: '"Tomáš Garnol"'
Publikováno v:
Acta Medica, Vol 59, Iss 2, Pp 35-42 (2016)
Aim: The aim of our study was to assess whether simple steatosis impairs liver regeneration after partial hepatectomy (PHx) in rats. Methods: Male Sprague–Dawley rats were fed a standard diet (ST-1, 10% kcal fat) and high-fat diet (HFD, 71% kcal fa
Externí odkaz:
https://doaj.org/article/f84ae6c24b2d4c3bb9e2d1d21c67c13e
Publikováno v:
Acta Medica, Vol 52, Iss 3, Pp 91-99 (2009)
Liver regeneration in mammals is a unique phenomenon attracting scientific interest for decades. It is a valuable model for basic biology research of cell cycle control as well as for clinically oriented studies of wide and heterogeneous group of liv
Externí odkaz:
https://doaj.org/article/8897aeecc41241318aa31aeb58778454
Publikováno v:
Scopus-Elsevier
Fatty liver disease associated with obesity is an important medical problem and the mechanisms for lipid accumulation in hepatocytes are not fully elucidated yet. Recent findings indicate that mitochondria play an important role in this process. Our
Autor:
Halka Lotková, Jirí Siller, Tomáš Garnol, Zuzana Červinková, Lukás Kohoutek, Tomáš Roušar, Otto Kucera
Publikováno v:
General Physiology and Biophysics. 29:72-78
S-adenosylmethionine (SAMe) is a key metabolite regulating growth, differentiation and death of hepatocytes. Experimentally, exogenous SAMe has been documented to attenuate hepatocar- cinogenesis. The aim of our study was to evaluate the effect of SA
Autor:
Otto Kucera, Zuzana Červinková, Tomáš Garnol, Tomáš Roušar, Halka Lotková, P Křiváková, René Endlicher
Publikováno v:
Acta Veterinaria Brno, Vol 78, Iss 4, Pp 603-613 (2009)
Acetaminophen (AAP) overdose causes severe liver injury and is the leading cause of acute liver injury in humans. The mechanisms participating in its toxic effect are glutathione depletion, oxidative stress and mitochondrial dysfunction. S-adenosylme
Autor:
Z Drahota, René Endlicher, Tomáš Garnol, Zuzana Červinková, Otto Kucera, Tomáš Roušar, Halka Lotková
Publikováno v:
Oxidative Medicine and Cellular Longevity
Oxidative Medicine and Cellular Longevity, Vol 2014 (2014)
Oxidative Medicine and Cellular Longevity, Vol 2014 (2014)
Oxidative stress and mitochondrial dysfunction play an important role in the pathogenesis of nonalcoholic fatty liver disease and toxic liver injury. The present study was designed to evaluate the effect of exogenous inducer of oxidative stress (tert
Publikováno v:
Acta Medica, Vol 52, Iss 3, Pp 91-99 (2009)
Scopus-Elsevier
Scopus-Elsevier
Liver regeneration in mammals is a unique phenomenon attracting scientific interest for decades. It is a valuable model for basic biology research of cell cycle control as well as for clinically oriented studies of wide and heterogeneous group of liv
Autor:
Halka Lotková, Tomáš Roušar, Zuzana Červinková, Tomáš Garnol, R Bolehovská, Otto Kucera, Pavla Staňková, Milos Hroch, Y Mazurová
Publikováno v:
ResearcherID
Scopus-Elsevier
Europe PubMed Central
Scopus-Elsevier
Europe PubMed Central
Non-alcoholic fatty liver disease (NAFLD) is an important cause of liver-related morbidity and mortality. The aim of this work was to establish and characterize a nutritional model of NAFLD in rats. Wistar or Sprague-Dawley male rats were fed ad libi
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::f30408033c8d7044c29f84ead4d18ce0
http://gateway.webofknowledge.com/gateway/Gateway.cgi?GWVersion=2&SrcAuth=ORCID&SrcApp=OrcidOrg&DestLinkType=FullRecord&DestApp=WOS_CPL&KeyUT=WOS:000291154900015&KeyUID=WOS:000291154900015
http://gateway.webofknowledge.com/gateway/Gateway.cgi?GWVersion=2&SrcAuth=ORCID&SrcApp=OrcidOrg&DestLinkType=FullRecord&DestApp=WOS_CPL&KeyUT=WOS:000291154900015&KeyUID=WOS:000291154900015