Zobrazeno 1 - 10
of 21
pro vyhledávání: '"Tomáš Chum"'
Autor:
Beena Varghese, José Alfredo González-Navarro, Valentino Libero Pio Guerra, Margarita Faizulina, Daria Artemieva, Tomáš Chum, Tejaswini Rama Bangalore Ramakrishna, Marek Cebecauer, Petr Kovaříček
Publikováno v:
iScience, Vol 27, Iss 11, Pp 111033- (2024)
Summary: Studying the complex realm of cellular communication and interactions by fluorescence microscopy requires sample fixation on a transparent substrate. To activate T cells, which are pivotal in controlling the immune system, it is important to
Externí odkaz:
https://doaj.org/article/11aa20a4eff343f3a7cf4af1508fa145
Autor:
Christian Franke, Tomáš Chum, Zuzana Kvíčalová, Daniela Glatzová, Gregor Jörg Gentsch, Alvaro Rodriguez, Dominic A. Helmerich, Lucas Herdly, Harsha Mavila, Otakar Frank, Tomáš Brdička, Sebastian van de Linde, Marek Cebecauer
Publikováno v:
Communications Biology, Vol 5, Iss 1, Pp 1-16 (2022)
A super-resolution localisation-based method is shown to map receptor topography in immune cells, which allows quantitative study of molecules and their interactions at the complex surface nanomorphology of cells.
Externí odkaz:
https://doaj.org/article/018fd2b6994b40ed8050d9016a61c5ee
Autor:
Jindřich Brejcha, Dagmar Bezděková, Nikola Čermáková, Saak V. Ovsepian, Petra Riegerová, Eva Mašínová, Marek Cebecauer, Martin Štefl, Tomáš Chum
Publikováno v:
Journal of Alzheimer's Disease
Neuroblastoma cell line SH-SY5Y, due to its capacity to differentiate into neurons, easy handling, and low cost, is a common experimental model to study molecular events leading to Alzheimer’s disease (AD). However, it is prevalently used in its un
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::10c7458ca92d0db5f9684a28f74e849b
http://gala.gre.ac.uk/id/eprint/34380/1/34380_Ovsepian_Expression_and_localisation_of_ABPP_in-SH-SY5Y_Cells_Depends_on.pdf
http://gala.gre.ac.uk/id/eprint/34380/1/34380_Ovsepian_Expression_and_localisation_of_ABPP_in-SH-SY5Y_Cells_Depends_on.pdf
Autor:
Tomas Brdicka, Daniela Glatzová, Maria Chiara Saija, Marek Cebecauer, Tomáš Chum, Lukasz Cwiklik, Harsha Mavila
LAT is a critical regulator of T cell development and function. It organises signalling events at the plasma membrane. However, the mechanism, which controls LAT localisation at the plasma membrane is not fully understood. Here, we studied the impact
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::0244526814c7b148a24f13e05216ce0d
https://doi.org/10.1101/2020.08.10.244251
https://doi.org/10.1101/2020.08.10.244251
Autor:
Christian Franke, Tomáš Chum, Zuzana Kvíčalová, Daniela Glatzová, Gregor Jörg Gentsch, Alvaro Rodriguez, Dominic A. Helmerich, Lucas Herdly, Harsha Mavila, Otakar Frank, Tomáš Brdička, Sebastian van de Linde, Marek Cebecauer
Publikováno v:
Communications biology. 5(1)
Cells communicate with their environment via surface receptors, but nanoscopic receptor organization with respect to complex cell surface morphology remains unclear. This is mainly due to a lack of accessible, robust and high-resolution methods. Here
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::3b8c58bf02fffc924580d3ba48380c83
https://pubmed.ncbi.nlm.nih.gov/35264712
https://pubmed.ncbi.nlm.nih.gov/35264712
Autor:
Daniele Fabris, Karel Valis, Jan Fiala, Jiří Cerny, Tomáš Chum, Marek Cebecauer, Růžena Filandrová, Petr Novák, Petr Man, Josef Chmelík, Michal Rosulek, Daniel Kavan, Lukáš Slavata
Publikováno v:
SSRN Electronic Journal.
Transcription enhancer activator domain (TEAD) transcription factors mediate gene expression regulation through interactions with M-CAT motif. They play an important role during development of nearly all eukaryotic organisms and control expression of
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::730ea15a3a08ddd786222ca57f81628f
https://doi.org/10.2139/ssrn.3640821
https://doi.org/10.2139/ssrn.3640821
Autor:
Daniela Glatzová, Tomáš Chum, Tomas Brdicka, Sebastian van de Linde, Christian Franke, Marek Cebecauer, Zuzana Kvíčalová, Dominic A. Helmerich, Otakar Frank, Alvaro Rodriguez
Cells communicate with the surrounding environment via receptors on their surface. However, it remains unclear how are receptors organized with respect to the complex cell surface morphology. This is mainly due to a lack of accessible, robust and hig
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::081c3aedd28a6573301dea1eba00dacd
https://doi.org/10.1101/2019.12.23.884460
https://doi.org/10.1101/2019.12.23.884460
Publikováno v:
Journal of cell science. 129(15)
Plasma membrane proteins synthesised at the endoplasmic reticulum are delivered to the cell surface via sorting pathways. Hydrophobic mismatch theory based on the length of the transmembrane domain (TMD) dominates discussion about determinants requir
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::dc719cd7b70bf50e8e27903d3817a149
https://pubmed.ncbi.nlm.nih.gov/26585312
https://pubmed.ncbi.nlm.nih.gov/26585312
Autor:
Jakub Hruška, Filip Oulehle, Tomáš Chuman, Tomáš Kolář, Michal Rybníček, Miroslav Trnka, William H McDowell
Publikováno v:
PLoS ONE, Vol 18, Iss 3, p e0256976 (2023)
The forests of central Europe have undergone remarkable transitions in the past 40 years as air quality has improved dramatically. Retrospective analysis of Norway spruce (Picea abies) tree rings in the Czech Republic shows that air pollution (e.g. S
Externí odkaz:
https://doaj.org/article/b8930bf952554408a72b6093dae4f460