Zobrazeno 1 - 10
of 14
pro vyhledávání: '"Tomáš Bobula"'
Autor:
Lenka Hejlová, Vladimír Velebný, Ivana Basarabová, Iva Dolečková, Pavlína Procházková, Hana Vágnerová, Tomáš Bobula, Radovan Buffa, Soňa Moravčíková, Petra Šedová
Publikováno v:
Carbohydrate Polymers. 163:247-253
Hyaluronic acid (HA) containing CC double bond in positions 4 and 5 of N-acetyl-glucosamine ring (ΔHA) is an unique material, which could be used for biomedical applications and cosmetics. The main advantage of the CC double bond is its ability to r
Autor:
Lenka Kohutová, Vladimír Velebný, Hana Vágnerová, Martin Čepa, Radovan Buffa, Pavlína Procházková, Lucie Wolfova, Tomáš Bobula, Martina Hermannová, Ondřej Židek
Publikováno v:
Carbohydrate Polymers. 161:277-285
A new photopolymerizable derivative of hyaluronan (methacrylhydrazide-HA, MAHA) was prepared by carbodiimide chemistry. The reaction conditions were optimized for molecular weight (Mw), reaction time and amount of reagents with a degree of methacryla
Autor:
Vladimír Velebný, Radovan Buffa, Petra Šedová, Tomáš Bobula, Martina Moravcová, Ivana Basarabová, Lucie Wolfova
Publikováno v:
Carbohydrate Polymers. 134:293-299
Hyaluronic acid (HA) modified with an aldehyde group (HA-CHO or HA-aldehyde) has been extensively used for various biomedical applications. The main advantage of the aldehyde moieties is the ability to react with a wide range of amino compounds under
Autor:
Iva Dolečková, Tomáš Bobula, Martina Hermannová, Hana Vágnerová, Radovan Buffa, Vladimír Velebný
Publikováno v:
Carbohydrate polymers. 190
Chondroitin sulfate (CS) was regio-specifically modified to an unsaturated derivative (ΔCS) with a double bond in positions 4 and 5 of N-acetyl-d-galactosamine. The structure of ΔCS was elucidated in detail by two dimensional nuclear magnetic reson
Publikováno v:
Tetrahedron. 66:530-536
An improved practical protocol for the synthesis of both anomers of 1-ethynyl-2-deoxiribosides 1 was developed. The Sonogashira coupling of ethynyldeoxyribosides 1 with various aryl- and heteroaryl halides was carried out under various conditions. It
Autor:
Róbert Gyepes, Jason Hudlický, Ivana Císařová, Tomáš Bobula, Martin Kotora, Petr Štěpnička, Petr Novák
Publikováno v:
European Journal of Inorganic Chemistry. 2008:3911-3920
Catalysts formed in situ from [Mo(CO)6] and halophenols in dichloromethane efficiently promote cross metathesis reactions of (prop-1-yn-1-yl)ferrocene with various functionalized alkynes to give the corresponding alkynylferrocenes with good selectivi
Publikováno v:
Journal of Heterocyclic Chemistry. 45:201-207
A new synthetic methodology towards substituted 2-amino-5-chlorothiophenes is described. Compounds of this type are important as building blocks for oligomers used in polymer research. Easily available 2-aminothiophenes underwent Paal-Knorr reaction
Autor:
Pavlína Procházková, Ondřej Židek, Romana Sulakova, Veronika Moravcová, Hana Vágnerová, Vladimír Velebný, Radovan Buffa, Tomáš Bobula
Publikováno v:
Carbohydrate polymers. 136
Chondroitin sulfate (CS) was chemoselectively oxidized by Tempo/NaClO to C-6 aldehyde of a D-galactosamine subunit (GalNAc). The subsequent, spontaneous desulfatation of oxidized CS gave rise to α,β-unsaturated aldehyde. A new derivative of CS was