Zobrazeno 1 - 10
of 138
pro vyhledávání: '"Tom, Wennekes"'
Autor:
Xuesheng Wu, Maite Goebbels, Oliver Debski-Antoniak, Katherine Marougka, Lemeng Chao, Tony Smits, Tom Wennekes, Frank J M van Kuppeveld, Erik de Vries, Cornelis A M de Haan
Publikováno v:
PLoS Pathogens, Vol 20, Iss 7, p e1012371 (2024)
Sialoglycan-binding enveloped viruses often possess receptor-destroying activity to avoid being immobilized by non-functional decoy receptors. Sialic acid (Sia)-binding paramyxoviruses contain a hemagglutinin-neuraminidase (HN) protein that possesses
Externí odkaz:
https://doaj.org/article/a454fd3ea19c4cc0b29688af08bcdb03
Autor:
Xuesheng Wu, Maite Goebbels, Lemeng Chao, Tom Wennekes, Frank J M van Kuppeveld, Erik de Vries, Cornelis A M de Haan
Publikováno v:
PLoS Pathogens, Vol 19, Iss 3, p e1011273 (2023)
Many viruses initiate infection by binding to sialoglycan receptors at the cell surface. Binding to such receptors comes at a cost, however, as the sheer abundance of sialoglycans e.g. in mucus, may immobilize virions to non-functional decoy receptor
Externí odkaz:
https://doaj.org/article/0aead2d786284e53a1848f3e2b1c72ef
Autor:
Meiling Dai, Wenjuan Du, Carles Martínez-Romero, Tim Leenders, Tom Wennekes, Guus F. Rimmelzwaan, Frank J. M. van Kuppeveld, Ron A. M. Fouchier, Adolfo Garcia-Sastre, Erik de Vries, Cornelis A. M. de Haan
Publikováno v:
mBio, Vol 12, Iss 3 (2021)
Since its emergence in 2009, the pandemic H1N1 influenza A virus (IAV) has caused significant disease and mortality in humans. IAVs contain two envelope glycoproteins, the receptor-binding hemagglutinin (HA) and the receptor-destroying neuraminidase
Externí odkaz:
https://doaj.org/article/163ddbb305ac4bb68f81dbc7e705a477
Autor:
Dani A C Heesterbeek, Remy M Muts, Vincent P van Hensbergen, Pieter de Saint Aulaire, Tom Wennekes, Bart W Bardoel, Nina M van Sorge, Suzan H M Rooijakkers
Publikováno v:
PLoS Pathogens, Vol 17, Iss 1, p e1009227 (2021)
Infections with Gram-negative bacteria form an increasing risk for human health due to antibiotic resistance. Our immune system contains various antimicrobial proteins that can degrade the bacterial cell envelope. However, many of these proteins do n
Externí odkaz:
https://doaj.org/article/3864237fc065485abe33d9b2af2ec38f
Autor:
Yvette M. C. A. Luijkx, Anniek J. Henselijn, Gerlof P. Bosman, Dario A. T. Cramer, Koen C. A. P. Giesbers, Esther M. van ‘t Veld, Geert-Jan Boons, Albert J. R. Heck, Karli R. Reiding, Karin Strijbis, Tom Wennekes
Publikováno v:
Molecules, Vol 27, Iss 5, p 1615 (2022)
Fucosidases are associated with several pathological conditions and play an important role in the health of the human gut. For example, fucosidases have been shown to be indicators and/or involved in hepatocellular carcinoma, breast cancer, and helic
Externí odkaz:
https://doaj.org/article/19948738367644a2b9b7bf31671957b2
Autor:
Martijn Fiers, Jorin Hoogenboom, Alice Brunazzi, Tom Wennekes, Gerco C. Angenent, Richard G. H. Immink
Publikováno v:
Plant Methods, Vol 13, Iss 1, Pp 1-9 (2017)
Abstract Background Floral timing is a carefully regulated process, in which the plant determines the optimal moment to switch from the vegetative to reproductive phase. While there are numerous genes known that control flowering time, little informa
Externí odkaz:
https://doaj.org/article/61a41c1a7da94c0e91344b6c9928b147
Autor:
Frederik Broszeit, Netanel Tzarum, Xueyong Zhu, Nikoloz Nemanichvili, Dirk Eggink, Tim Leenders, Zeshi Li, Lin Liu, Margreet A. Wolfert, Andreas Papanikolaou, Carles Martínez-Romero, Ivan A. Gagarinov, Wenli Yu, Adolfo García-Sastre, Tom Wennekes, Masatoshi Okamatsu, Monique H. Verheije, Ian A. Wilson, Geert-Jan Boons, Robert P. de Vries
Publikováno v:
Cell Reports, Vol 27, Iss 11, Pp 3284-3294.e6 (2019)
Summary: A species barrier for the influenza A virus is the differential expression of sialic acid, which can either be α2,3-linked for avians or α2,6-linked for human viruses. The influenza A virus hosts also express other species-specific sialic
Externí odkaz:
https://doaj.org/article/356c85208c314c13a5226260677637ce
Autor:
Omid Karami, Hanna de Jong, Victor J. Somovilla, Beatriz Villanueva Acosta, Aldo Bryan Sugiarta, Tom Wennekes, Remko Offringa
2,4-dichlorophenoxyacetic acid (2,4-D) is a synthetic analogue of the plant hormone auxin that is commonly used in many in vitro plant regeneration systems, such as somatic embryogenesis (SE). Its effectiveness in inducing SE, compared to the natural
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::f986d5b4c0e666d4d669606c4957c662
https://doi.org/10.1101/2022.08.17.504315
https://doi.org/10.1101/2022.08.17.504315
Autor:
Anton P. Bussink, Paul F. van Swieten, Karen Ghauharali, Saskia Scheij, Marco van Eijk, Tom Wennekes, Gijs A. van der Marel, Rolf G. Boot, Johannes M.F.G. Aerts, Herman S. Overkleeft
Publikováno v:
Journal of Lipid Research, Vol 48, Iss 6, Pp 1417-1421 (2007)
Peracetylated N-α-azidoacetylmannosamine (Ac4ManNAz) is metabolized by cells to CMP-azidosialic acid. It has been demonstrated previously that in this way azidosialic acid-containing glycoproteins are formed that can be labeled on the cell surface b
Externí odkaz:
https://doaj.org/article/66c6502612744bc7b882a6938d45887c
Publikováno v:
EMBO Reports, 22(3):e52162. Nature Publishing Group
Understanding the mechanisms by which natural anti-freeze proteins protect cells and tissues from cold could help to improve the availability of donor organs for transplantation.
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::e7db23ab9e8b4cafe904cb7cdd3a2cd3
https://doi.org/10.15252/embr.202052162
https://doi.org/10.15252/embr.202052162