Zobrazeno 1 - 10
of 84
pro vyhledávání: '"Tom, Parks"'
Autor:
Haiko Schurz, Vivek Naranbhai, Tom A Yates, James J Gilchrist, Tom Parks, Peter J Dodd, Marlo Möller, Eileen G Hoal, Andrew P Morris, Adrian VS Hill, International Tuberculosis Host Genetics Consortium
Publikováno v:
eLife, Vol 13 (2024)
The heritability of susceptibility to tuberculosis (TB) disease has been well recognized. Over 100 genes have been studied as candidates for TB susceptibility, and several variants were identified by genome-wide association studies (GWAS), but few re
Externí odkaz:
https://doaj.org/article/00c3c9bd8aaa466cb16976111e168c78
Autor:
Andrew C Steer, Samantha M Colquhoun, Tom Parks, Daniel Engelman, Mai ling Perman, Kelera Sakumeni, Litia Narube, James J Fong, Joseph Kado
Publikováno v:
BMJ Open, Vol 13, Iss 4 (2023)
Objective To determine population-based rates of non-fatal complications of rheumatic heart disease (RHD).Design Retrospective cohort study based on multiple sources of routine clinical and administrative data amalgamated by probabilistic record-link
Externí odkaz:
https://doaj.org/article/feaef091b17d4dd1bdf74551cc53ce92
Autor:
James J Gilchrist, Kathryn Auckland, Tom Parks, Alexander J Mentzer, Lily Goldblatt, Vivek Naranbhai, Gavin Band, Kirk A Rockett, Ousmane B Toure, Salimata Konate, Sibiri Sissoko, Abdoulaye A Djimdé, Mahamadou A Thera, Ogobara K Doumbo, Samba Sow, Sian Floyd, Jörg M Pönnighaus, David K Warndorff, Amelia C Crampin, Paul E M Fine, Benjamin P Fairfax, Adrian V S Hill
Publikováno v:
PLoS Pathogens, Vol 18, Iss 9, p e1010312 (2022)
Leprosy is a chronic infection of the skin and peripheral nerves caused by Mycobacterium leprae. Despite recent improvements in disease control, leprosy remains an important cause of infectious disability globally. Large-scale genetic association stu
Externí odkaz:
https://doaj.org/article/1b686b47b5c44125a70cea80ed468575
Autor:
Emmy Okello, Craig Sable, Andrea Z Beaton, Chris T Longenecker, Jonathan Carapetis, Joselyn Rwebembera, Jenifer Atala, Emma Ndagire, Tom Parks, Jafesi Pulle, Rachel Sarnacki, Nicholas Ollberding, Asha Bowen, Collins Agaba, Murali Meghna, Rosemary Kansiime, Linda Oyella, Huaiyu Zang
Publikováno v:
BMJ Open, Vol 12, Iss 3 (2022)
Externí odkaz:
https://doaj.org/article/fa631c5a7d234680a6ecc54abbd413cb
Autor:
Oscar L. Rodriguez, William S. Gibson, Tom Parks, Matthew Emery, James Powell, Maya Strahl, Gintaras Deikus, Kathryn Auckland, Evan E. Eichler, Wayne A. Marasco, Robert Sebra, Andrew J. Sharp, Melissa L. Smith, Ali Bashir, Corey T. Watson
Publikováno v:
Frontiers in Immunology, Vol 11 (2020)
An incomplete ascertainment of genetic variation within the highly polymorphic immunoglobulin heavy chain locus (IGH) has hindered our ability to define genetic factors that influence antibody-mediated processes. Due to locus complexity, standard hig
Externí odkaz:
https://doaj.org/article/898d5da7ab434af3b8fb0d021effc906
Autor:
Emmy Okello, Emma Ndagire, Jenifer Atala, Asha C. Bowen, Marc P. DiFazio, Nada S. Harik, Chris T. Longenecker, Peter Lwabi, Meghna Murali, Scott A. Norton, Isaac Otim Omara, Linda Mary Oyella, Tom Parks, Jafesi Pulle, Joselyn Rwebembera, Rachel J. Sarnacki, Christopher F. Spurney, Elizabeth Stein, Laura Tochen, David Watkins, Meghan Zimmerman, Jonathan R. Carapetis, Craig Sable, Andrea Beaton
Publikováno v:
Journal of the American Heart Association: Cardiovascular and Cerebrovascular Disease, Vol 9, Iss 15 (2020)
Background Despite the high burden of rheumatic heart disease in sub‐Saharan Africa, diagnosis with acute rheumatic fever (ARF) is exceedingly rare. Here, we report the results of the first prospective epidemiologic survey to diagnose and character
Externí odkaz:
https://doaj.org/article/434a42a6356f428a9077a9e6e8e18b5d
Autor:
Kate M Miller, Theresa Lamagni, Thomas Cherian, Jeffrey W Cannon, Tom Parks, Richard A Adegbola, Janessa Pickering, Tim Barnett, Mark E Engel, Laurens Manning, Asha C Bowen, Jonathan R Carapetis, Hannah C Moore, Dylan D Barth, David C Kaslow, Chris A Van Beneden
Publikováno v:
S40
S31
S31
Invasive group A streptococcal (Strep A) infections occur when Streptococcus pyogenes, also known as beta-hemolytic group A Streptococcus, invades a normally sterile site in the body. This article provides guidelines for establishing surveillance for
Autor:
Tom Parks, Mariana M. Mirabel, Joseph Kado, Kathryn Auckland, Jaroslaw Nowak, Anna Rautanen, Alexander J. Mentzer, Eloi Marijon, Xavier Jouven, Mai Ling Perman, Tuliana Cua, John K. Kauwe, John B. Allen, Henry Taylor, Kathryn J. Robson, Charlotte M. Deane, Andrew C. Steer, Adrian V. S. Hill, Pacific Islands Rheumatic Heart Disease Genetics Network
Publikováno v:
Nature Communications, Vol 8, Iss 1, Pp 1-10 (2017)
Rheumatic heart disease (RHD) is a chronic auto-inflammatory reaction to group A streptococcal infection, and frequently occurs in individuals from the South Pacific. This study finds a novel association between an immunoglobulin heavy chain allele a
Externí odkaz:
https://doaj.org/article/f1a3562bc39247d39047f5629a43276b
Autor:
Alexander J. Mentzer, Alexander T. Dilthey, Martin Pollard, Deepti Gurdasani, Emre Karakoc, Tommy Carstensen, Allan Muhwezi, Clare Cutland, Amidou Diarra, Ricardo da Silva Antunes, Sinu Paul, Gaby Smits, Susan Wareing, HwaRan Kim, Cristina Pomilla, Amanda Y. Chong, Debora Y.C. Brandt, Rasmus Nielsen, Samuel Neaves, Nicolas Timpson, Austin Crinklaw, Cecilia S. Lindestam Arlehamn, Anna Rautanen, Dennison Kizito, Tom Parks, Kathryn Auckland, Kate E. Elliott, Tara Mills, Katie Ewer, Nick Edwards, Segun Fatumo, Sarah Peacock, Katie Jeffery, Fiona R.M. van der Klis, Pontiano Kaleebu, Pandurangan Vijayanand, Bjorn Peters, Alessandro Sette, Nezih Cereb, Sodiomon Sirima, Shabir A. Madhi, Alison M. Elliott, Gil McVean, Adrian V.S. Hill, Manjinder S. Sandhu
How human genetic variation contributes to vaccine immunogenicity and effectiveness is unclear, particularly in infants from Africa. We undertook genome-wide association analyses of eight vaccine antibody responses in 2,499 infants from three African
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::6d03a43aecccb408d4ee8b3d67cc171a
https://doi.org/10.1101/2022.11.24.22282715
https://doi.org/10.1101/2022.11.24.22282715
Autor:
Fergus Hamilton, Alexander Mentzer, Tom Parks, J Kenneth Baillie, George Davey Smith, Peter Ghazal, Nicholas J Timpson
IntroductionERAP2is an aminopeptidase involved in immunological antigen presentation. Genotype data in human samples from before and after the Black Death, an epidemic due toYersinia pestis, have marked changes in population allele frequency of the c
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::fc6c5b9766ace8b5beb97970f4b27c0c
https://doi.org/10.1101/2022.11.04.22281942
https://doi.org/10.1101/2022.11.04.22281942