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Developmental alterations in Huntington's disease neural cells and pharmacological rescue in cells and mice

Autor: HD iPSC Consortium, Lim, Ryan G, Salazar, Lisa L, Wilton, Daniel K, King, Alvin R, Stocksdale, Jennifer T, Sharifabad, Delaram, Lau, L Alice, Stevens, Beth, Reidling, Jack C, Winokur, Sara T, Casale, Malcolm S, Thompson, Leslie M, Pardo, Mónica, Díaz-Barriga, A Gerardo García, Straccia, Marco, Sanders, Phil, Alberch, Jordi, Canals, Josep M, Kaye, Julia A, Dunlap, Mariah, Jo, Lisa, May, Hanna, Mount, Elliot, Anderson-Bergman, Cliff, Haston, Kelly, Finkbeiner, Steven, Allen, Nicholas D, Kemp, Paul J, Atwal, Ranjit Singh, Biagioli, Marta, Gusella, James F, MacDonald, Marcy E, Akimov, Sergey S, Arbez, Nicolas, Stewart, Jacqueline, Ross, Christopher A, Mattis, Virginia B, Tom, Colton M, Ornelas, Loren, Sahabian, Anais, Lenaeus, Lindsay, Mandefro, Berhan, Sareen, Dhruv, Svendsen, Clive N, Kedaigle, Amanda Joy, Wasylenko, Theresa Anne, Yildirim, Ferah, Ng, Christopher W., Milani, Pamela, Housman, David E, Fraenkel, Ernest

Publikováno v: Lim, RG; Salazar, LL; Wilton, DK; King, AR; Stocksdale, JT; Sharifabad, D; et al.(2017). Developmental alterations in Huntington's disease neural cells and pharmacological rescue in cells and mice. Nature Neuroscience, 20(5), 648-660. doi: 10.1038/nn.4532. UC San Francisco: Retrieved from: http://www.escholarship.org/uc/item/0b73w87p
PMC
Recercat. Dipósit de la Recerca de Catalunya
instname
Dipòsit Digital de la UB
Universidad de Barcelona

Neural cultures derived from Huntington's disease (HD) patient-derived induced pluripotent stem cells were used for 'omics' analyses to identify mechanisms underlying neurodegeneration. RNA-seq analysis identified genes in glutamate and GABA signalin

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::fb6a594baf1d75f869aa29d0096e1d45
https://doi.org/10.1038/nn.4532

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Will We Ever Meet Again? : A Bridge Between This World and the Next

Autor: Tom Colton

Do you ever wonder what happens after death? Do you believe in life after death? In this candid and straight-talking book, the author shares his own journey into mediumship and his work with various development circles and other groups. We get a uniq

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