Objective comparison of methods to decode anomalous diffusion

Autor: Gorka Muñoz-Gil, Giovanni Volpe, Miguel Angel Garcia-March, Erez Aghion, Aykut Argun, Chang Beom Hong, Tom Bland, Stefano Bo, J. Alberto Conejero, Nicolás Firbas, Òscar Garibo i Orts, Alessia Gentili, Zihan Huang, Jae-Hyung Jeon, Hélène Kabbech, Yeongjin Kim, Patrycja Kowalek, Diego Krapf, Hanna Loch-Olszewska, Michael A. Lomholt, Jean-Baptiste Masson, Philipp G. Meyer, Seongyu Park, Borja Requena, Ihor Smal, Taegeun Song, Janusz Szwabiński, Samudrajit Thapa, Hippolyte Verdier, Giorgio Volpe, Artur Widera, Maciej Lewenstein, Ralf Metzler, Carlo Manzo

Publikováno v: Nature Communications, Vol 12, Iss 1, Pp 1-16 (2021)

Deviations from Brownian motion leading to anomalous diffusion are ubiquitously found in transport dynamics but often difficult to characterize. Here the authors compare approaches for single trajectory analysis through an open competition, showing t

Externí odkaz: https://doaj.org/article/5fe8e471b0bb497ab6891805cdc7e577

An analog sensitive allele permits rapid and reversible chemical inhibition of PKC-3 activity in

Autor: KangBo, Ng, Tom, Bland, Nisha, Hirani, Nathan W, Goehring

Publikováno v: microPublication biology. 2022

Much of our understanding of PAR polarity comes from experiments performed in C. elegans zygotes, in which RNAi allows highly efficient depletion of the relevant players, including the key polarity kinase atypical protein kinase C (PKC-3 in C. elegan

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::f305c83efe55c3414f48b4c566f77657
https://pubmed.ncbi.nlm.nih.gov/35996692

SAIBR: A simple, platform-independent method for spectral autofluorescence correction

Autor: Nelio T.L. Rodrigues, Tom Bland, Joana Borrego-Pinto, KangBo Ng, Nisha Hirani, Ying Gu, Sherman Foo, Nathan W. Goehring

Biological systems are increasingly viewed through the lens of mathematics, physics, and systems approaches that demand accurate quantification of gene expression and local protein concentrations. Such approaches have benefited greatly from the revol

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_________::c7f6ef85596b0dacf16fecff669eb424
https://doi.org/10.1101/2022.01.19.476881

Objective comparison of methods to decode anomalous diffusion

Autor: Samudrajit Thapa, Òscar Garibo i Orts, Yeongjin Kim, Taegeun Song, Erez Aghion, Stefano Bo, Tom Bland, Ralf Metzler, Nicolas Firbas, Maciej Lewenstein, Janusz Szwabiński, Seongyu Park, Giovanni Volpe, Artur Widera, Borja Requena, Philipp G. Meyer, Alessia Gentili, Giorgio Volpe, Jae-Hyung Jeon, Aykut Argun, Jean-Baptiste Masson, Ihor Smal, Hippolyte Verdier, Hanna Loch-Olszewska, Miguel Ángel García-March, Patrycja Kowalek, Carlo Manzo, Michael A. Lomholt, Diego Krapf, Gorka Muñoz-Gil, Chang Beom Hong, Zihan Huang, Hélène Kabbech, J. Alberto Conejero

Publikováno v: Nature Communications, Vol 12, Iss 1, Pp 1-16 (2021)
Nature Communications
Nature Communications, 12(1):6253. Nature Publishing Group
Muñoz-Gil, G, Volpe, G, Garcia-March, M A, Aghion, E, Argun, A, Hong, C B, Bland, T, Bo, S, Conejero, J A, Firbas, N, Garibo i Orts, Ò, Gentili, A, Huang, Z, Jeon, J H, Kabbech, H, Kim, Y, Kowalek, P, Krapf, D, Loch-Olszewska, H, Lomholt, M A, Masson, J B, Meyer, P G, Park, S, Requena, B, Smal, I, Song, T, Szwabiński, J, Thapa, S, Verdier, H, Volpe, G, Widera, A, Lewenstein, M, Metzler, R & Manzo, C 2021, ' Objective comparison of methods to decode anomalous diffusion ', Nature Communications, vol. 12, no. 1, 6253 . https://doi.org/10.1038/s41467-021-26320-w

Deviations from Brownian motion leading to anomalous diffusion are ubiquitously found in transport dynamics, playing a crucial role in phenomena from quantum physics to life sciences. The detection and characterization of anomalous diffusion from the

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::589e281d9c03358990254ce07833f8ae
https://doi.org/10.1038/s41467-021-26320-w

Anterior-enriched filopodia create the appearance of asymmetric membrane microdomains in polarizing

Autor: Nisha, Hirani, Rukshala, Illukkumbura, Tom, Bland, Grégoire, Mathonnet, Delphine, Suhner, Anne-Cecile, Reymann, Nathan W, Goehring

Publikováno v: Journal of Cell Science

The association of molecules within membrane microdomains is critical for the intracellular organization of cells. During polarization of the C. elegans zygote, both polarity proteins and actomyosin regulators associate within dynamic membrane-associ

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=pmid________::6e9f8f3328e5adccf7438666b1829b95
https://pubmed.ncbi.nlm.nih.gov/31221727