Zobrazeno 1 - 10
of 202
pro vyhledávání: '"Tom, Böhling"'
Publikováno v:
Scientific Reports, Vol 12, Iss 1, Pp 1-8 (2022)
Abstract Eccrine porocarcinoma (EPC) is a rare malignant adnexal tumour of the skin. Part of EPCs develop from their benign counterpart, poroma (EP), with chronic light exposure and immunosuppression hypothesized to play a role in the malignant trans
Externí odkaz:
https://doaj.org/article/99dd7dc725934cc18ee3063005cac510
Autor:
Marko Salmikangas, Maria Laaksonen, Henrik Edgren, Marco Salgado, Anu Suoranta, Pirkko Mattila, Virve Koljonen, Tom Böhling, Harri Sihto
Publikováno v:
PLoS ONE, Vol 18, Iss 5, p e0285524 (2023)
Merkel cell carcinoma (MCC) is a rare cutaneous neuroendocrine carcinoma that is frequently divided into Merkel cell polyomavirus negative and positive tumors due their distinct genomic and transcriptomic profiles, and disease outcomes. Although some
Externí odkaz:
https://doaj.org/article/b73c83bccbc64b178f32e9e4e9d24760
Autor:
Klaus W Fagerstedt, Tom Böhling, Harri Sihto, Tarja Salonen, Fang Zhao, Mia Kero, Leif C Andersson, Johanna Arola
Publikováno v:
Endocrine Connections, Vol 10, Iss 9, Pp 1055-1064 (2021)
Mixed neuroendocrine-non-neuroendocrine neoplasms (MINEN) are rare tumors that consist of at least 30% of both neuroendocrine and non-neuroendocrine components. The data concerning the pathogenesis of MINEN suggest a monoclonal origin. We describe a
Externí odkaz:
https://doaj.org/article/baa7f4ad70af4838bd6c0143f8f71647
Autor:
Eeva Kettunen, Sauli Savukoski, Kaisa Salmenkivi, Tom Böhling, Esa Vanhala, Eeva Kuosma, Sisko Anttila, Henrik Wolff
Publikováno v:
BMC Cancer, Vol 19, Iss 1, Pp 1-10 (2019)
Abstract Background Deletion of the CDKN2A locus is centrally involved in the development of several malignancies. In malignant pleural mesothelioma (MPM), it is one of the most frequently reported genomic alteration. MPM is strongly associated with
Externí odkaz:
https://doaj.org/article/131cca9545364481bce20e538437397f
Publikováno v:
PLoS ONE, Vol 16, Iss 5, p e0252099 (2021)
Merkel cell carcinoma (MCC) is a rare skin cancer with only limited therapeutic options for advanced disease. We previously showed that oncogene ALK is frequently expressed at the RNA level in MCC and further that ALK positivity by immunohistochemist
Externí odkaz:
https://doaj.org/article/1ba0b773467f4185a9e5fb91ca628588
Publikováno v:
Acta Dermato-Venereologica, Vol 101, Iss 1, p adv00363 (2021)
Malignant eccrine porocarcinoma is a rare skin adnexal cancer arising from the sweat glands. Little is known about the epidemiology and incidence of eccrine porocarcinoma. This registry-based study examined the epidemiology and incidence data for ecc
Externí odkaz:
https://doaj.org/article/866ba9e184b8421095eadb1bd5c6aab9
Publikováno v:
International journal of cancer.
Merkel cell carcinoma (MCC) is a cutaneous neuroendocrine malignancy with a poor prognosis and an unknown cell of origin. Proffered cells of origin include epithelial stem cells of the hair follicle or interfollicular epidermis, dermal stem cells and
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::05cb440d7c5baea2b92f07db1e205e4c
https://pubmed.ncbi.nlm.nih.gov/36620996
https://pubmed.ncbi.nlm.nih.gov/36620996
Publikováno v:
Cancers; Volume 14; Issue 15; Pages: 3591
Background: Merkel cell carcinoma (MCC) is a rare but highly aggressive neuroendocrine carcinoma of the skin with a poor prognosis. Improving the prognosis of MCC by means of targeted therapies requires further understanding of the mechanisms that dr
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::d3fb2becef4989ac9bc24a6b081c275f
Autor:
Heikki Joensuu, Sirpa Jalkanen, Marko Salmi, Virve Koljonen, Heli Kavola, Tom Böhling, Harri Sihto
PDF file, 24KB, Associations of tumor infiltrating CD16+ natural killer cells, CD68+ macrophages, and CD163+ macrophages with patient and tumor characteristics.
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::490d4c2e6c6f01e1210b502712d39099
https://doi.org/10.1158/1078-0432.22444487
https://doi.org/10.1158/1078-0432.22444487
Purpose: Merkel cell carcinoma (MCC) is rare skin cancer that is often associated with Merkel cell polyomavirus (MCPyV) infection. Polyomaviruses repress tumor suppressor proteins, thus influencing cell-cycle progression, but the effect of MCPyV on t
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::41b6a956aab5855ada7869a7b99f88c0
https://doi.org/10.1158/1078-0432.c.6519617.v1
https://doi.org/10.1158/1078-0432.c.6519617.v1