Zobrazeno 1 - 10
of 21
pro vyhledávání: '"Tom, Aschman"'
Autor:
Tom Aschman, Emanuel Wyler, Oliver Baum, Andreas Hentschel, Rebekka Rust, Franziska Legler, Corinna Preusse, Lil Meyer-Arndt, Ivana Büttnerova, Alexandra Förster, Derya Cengiz, Luiz Gustavo Teixeira Alves, Julia Schneider, Claudia Kedor, Judith Bellmann-Strobl, Aminaa Sanchin, Hans-Hilmar Goebel, Markus Landthaler, Victor Corman, Andreas Roos, Frank L. Heppner, Helena Radbruch, Friedemann Paul, Carmen Scheibenbogen, Nora F. Dengler, Werner Stenzel
Publikováno v:
Acta Neuropathologica Communications, Vol 11, Iss 1, Pp 1-20 (2023)
Abstract The SARS-CoV-2 pandemic not only resulted in millions of acute infections worldwide, but also in many cases of post-infectious syndromes, colloquially referred to as “long COVID”. Due to the heterogeneous nature of symptoms and scarcity
Externí odkaz:
https://doaj.org/article/b65fc0fea9634e6a9d9eb0b43f7c5637
Autor:
Ronja Mothes, Anna Pascual-Reguant, Ralf Koehler, Juliane Liebeskind, Alina Liebheit, Sandy Bauherr, Lars Philipsen, Carsten Dittmayer, Michael Laue, Regina von Manitius, Sefer Elezkurtaj, Pawel Durek, Frederik Heinrich, Gitta A. Heinz, Gabriela M. Guerra, Benedikt Obermayer, Jenny Meinhardt, Jana Ihlow, Josefine Radke, Frank L. Heppner, Philipp Enghard, Helena Stockmann, Tom Aschman, Julia Schneider, Victor M. Corman, Leif E. Sander, Mir-Farzin Mashreghi, Thomas Conrad, Andreas C. Hocke, Raluca A. Niesner, Helena Radbruch, Anja E. Hauser
Publikováno v:
Nature Communications, Vol 14, Iss 1, Pp 1-16 (2023)
Infection with SARS-CoV-2 has been linked with substantive inflammation, lung pathology and development of COVID-19. Here the authors spatially associate CCL18 and CCL21 in distinct tissue niches with lung pathology of severe COVID-19.
Externí odkaz:
https://doaj.org/article/1b2247b6d5234d329b89d09ddd2a8d84
Autor:
Selina Greuel, Jana Ihlow, Mihnea-Paul Dragomir, Simon Streit, Victor Max Corman, Linus Haberbosch, David Winkler, Jenny Meinhardt, Tom Aschman, Julia Schneider, Iryna Trotsyuk, Catarina Alisa Kunze, Lukas Maurer, Helena Radbruch, Frank L. Heppner, David Horst, Sefer Elezkurtaj
Publikováno v:
International Journal of Infectious Diseases, Vol 108, Iss , Pp 274-281 (2021)
Objectives: Studies on coronavirus disease 2019 (COVID-19) usually focus on middle-aged and older adults. However, younger patients may present with severe COVID-19 with potentially fatal outcomes. For optimized, more specialized therapeutic regimens
Externí odkaz:
https://doaj.org/article/0595539e3f164cfe9a2ebafdf53c9a07
Autor:
Nils C. Gassen, Jan Papies, Thomas Bajaj, Jackson Emanuel, Frederik Dethloff, Robert Lorenz Chua, Jakob Trimpert, Nicolas Heinemann, Christine Niemeyer, Friderike Weege, Katja Hönzke, Tom Aschman, Daniel E. Heinz, Katja Weckmann, Tim Ebert, Andreas Zellner, Martina Lennarz, Emanuel Wyler, Simon Schroeder, Anja Richter, Daniela Niemeyer, Karen Hoffmann, Thomas F. Meyer, Frank L. Heppner, Victor M. Corman, Markus Landthaler, Andreas C. Hocke, Markus Morkel, Nikolaus Osterrieder, Christian Conrad, Roland Eils, Helena Radbruch, Patrick Giavalisco, Christian Drosten, Marcel A. Müller
Publikováno v:
Nature Communications, Vol 12, Iss 1, Pp 1-15 (2021)
Viruses manipulate host cell pathways to support infection. Here the authors show that SARS-CoV-2 infection modulates cellular metabolism and limits autophagy, and identify druggable host pathways for virus inhibition.
Externí odkaz:
https://doaj.org/article/a210cbf8766241fd8d824076b3b287b5
Autor:
Tom Aschman, Sandra Schaffer, Stylianos Iason Biniaris Georgallis, Antigoni Triantafyllopoulou, Peter Staeheli, Reinhard E. Voll
Publikováno v:
International Journal of Molecular Sciences, Vol 22, Iss 21, p 11747 (2021)
A pivotal role of type I interferons in systemic lupus erythematosus (SLE) is widely accepted. Type III interferons (IFN-λ) however, the most recently discovered cytokines grouped within the interferon family, have not been extensively studied in lu
Externí odkaz:
https://doaj.org/article/936f250686fe4ba3bc38e5efd943088c
Autor:
Tom Aschman, Werner Stenzel
Publikováno v:
Current Opinion in Neurology. 35:622-628
The global spread of severe acute respiratory syndrome coronavirus 2 resulted in many cases of acute and postacute muscular symptoms. In this review, we try to decipher the potential underlying pathomechanisms and summarize the potential links betwee
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::87fbe182b703c921164eb75ab3d3e2b2
https://doi.org/10.1097/wco.0000000000001101
https://doi.org/10.1097/wco.0000000000001101
Autor:
Tom Aschman, Emanuel Wyler, Oliver Baum, Andreas Hentschel, Franziska Legler, Corinna Preusse, Lil Meyer-Arndt, Ivana Büttnerova, Alexandra Förster, Derya Cengiz, Luiz Gustavo Teixeira Alves, Julia Schneider, Claudia Kedor, Rebecca Rust, Judith Bellmann-Strobl, Sanchin Aminaa, Peter Vajkoczy, Hans-Hilmar Goebel, Markus Landthaler, Victor Corman, Andreas Roos, Frank L. Heppner, Helena Radbruch, Friedemann Paul, Carmen Scheibenbogen, Werner Stenzel, Nora F. Dengler
The SARS-CoV-2 pandemic not only resulted in millions of acute infections worldwide, but also caused innumerable cases of post-infectious syndromes, colloquially referred to as “long COVID”. Due to the heterogeneous nature of symptoms and scarcit
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::6d3ea20a0919d15179dac253449596cd
https://doi.org/10.1101/2023.02.15.23285584
https://doi.org/10.1101/2023.02.15.23285584
Autor:
Josefine Radke, Jenny Meinhardt, Tom Aschman, Robert Lorenz Chua, Vadim Farztdinov, Sören Lukkassen, Foo Wei Ten, Ekaterina Friebel, Naveed Ishaque, Jonas Franz, Valerie Helena Huhle, Ronja Mothes, Kristin Peters, Carolina Thomas, Simon Streit, Regina von Manitius, Péter Körtvélyessy, Stefan Vielhaber, Dirk Reinhold, Anja Hauser, Anja Osterloh, Philipp Enghard, Jana Ihlow, Sefer Elezkurtaj, David Horst, Florian Kurth, Marcel A. Müller, Nils C. Gassen, Julia Schneider, Katharina Jechow, Bernd Timmermann, Camila Fernandez-Zapata, Chotima Böttcher, Werner Stenzel, Emanuel Wyler, Victor Corman, Christine Stadelmann-Nessler, Markus Ralser, Roland Eils, Frank L. Heppner, Michael Mülleder, Christian Conrad, Helena Radbruch
In COVID-19 neurological alterations are noticed during the systemic viral infection. Various pathophysiological mechanisms on the central nervous system (CNS) have been suggested in the past two years, including the viral neurotropism hypothesis. Ne
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::24c5414abe1f7853a3ba61674136c250
https://doi.org/10.1101/2023.01.16.22283804
https://doi.org/10.1101/2023.01.16.22283804
Autor:
Gitta Anne Heinz, Josefine Radke, Sophie Mc Ewen, V. Moos, Jobst Roehmel, Tilmann Kallinich, Pawel Durek, Daniela Niemeyer, Leif G. Hanitsch, Florian Kurth, Thordis Hohnstein, Uwe Kölsch, Mario Witkowski, Philipp Nawrath, Marcus A. Mall, Frederik Heinrich, Leif E. Sander, Stefan Frischbutter, Mir-Farzin Mashreghi, Tom Aschman, Emanuela Marcenaro, Victor M. Corman, Edoardo Viviano, Sascha Treskatsch, Andreas Diefenbach, Marta Ferreira-Gomes, Marcus Maurer, Christian Meisel, Caroline Tizian, Robert Lorenz Chua, Claudia U. Duerr, Stefan Angermair, Andrey Kruglov, Helena Radbruch, Birgit Sawitzki, Silvia Zocche, Christian Conrad, Andreas Radbruch, Irene Mattiola, Joseph A. Trapani, Thomas Schneider, Christian Drosten, Terry Jones, Kristina Allers
Publikováno v:
Nature. 600:295-301
SARS-CoV-2 is a single-stranded RNA virus that causes coronavirus disease 2019 (COVID-19). Given its acute and often self-limiting course, components of the innate immune system are likely central in controlling virus replication thereby determining
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::e8ef4688f094e8d16773050add62ca69
https://doi.org/10.1038/s41586-021-04142-6
https://doi.org/10.1038/s41586-021-04142-6
Autor:
Ronja Mothes, Anna Pascual-Reguant, Ralf Koehler, Juliane Liebeskind, Alina Liebheit, Sandy Bauherr, Carsten Dittmayer, Michael Laue, Regina von Manitius, Sefer Elezkurtaj, Pawel Durek, Frederik Heinrich, Gitta Anne Heinz, Gabriela Maria Guerra, Benedikt Obermayer, Jenny Meinhardt, Jana Ihlow, Josefine Radke, Frank L. Heppner, Philipp Enghard, Helena Stockmann, Tom Aschman, Julia Schneider, Victor Corman, Leif Erik Sander, Mir-Farzin Mashreghi, Thomas Conrad, Andreas Hocke, Raluca A. Niesner, Helena Radbruch, Anja E. Hauser
Post-acute lung sequelae of COVID-19 are challenging many survivors across the world, yet the mechanisms behind are poorly understood. Our results delineate an inflammatory cascade of events occurring along disease progression within fibrovascular ni
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::9cec82aaf6c768375804a73d0e6beea0
https://doi.org/10.1101/2022.03.24.22272768
https://doi.org/10.1101/2022.03.24.22272768