Zobrazeno 1 - 10
of 665
pro vyhledávání: '"Tolun, P. a"'
Autor:
Zhi-Qiang Xu, Slobodan Jergic, Allen T. Y. Lo, Alok C. Pradhan, Simon H. J. Brown, James C. Bouwer, Harshad Ghodke, Peter J. Lewis, Gökhan Tolun, Aaron J. Oakley, Nicholas E. Dixon
Publikováno v:
Nature Communications, Vol 15, Iss 1, Pp 1-14 (2024)
Abstract Ring-shaped DNA sliding clamps are essential for DNA replication and genome maintenance. Clamps need to be opened and chaperoned onto DNA by clamp loader complexes (CLCs). Detailed understanding of the mechanisms by which CLCs open and place
Externí odkaz:
https://doaj.org/article/9e8880c9aa2c40dbb2212545d9c48737
Publikováno v:
Engineering Microbiology, Vol 4, Iss 1, Pp 100120- (2024)
Recombineering is an essential tool for molecular biologists, allowing for the facile and efficient manipulation of bacterial genomes directly in cells without the need for costly and laborious in vitro manipulations involving restriction enzymes. Th
Externí odkaz:
https://doaj.org/article/26db5ad3b59847bd925a78c8f3e21d7a
Publikováno v:
Türk Biyokimya Dergisi, Vol 49, Iss 2, Pp 157-166 (2023)
Complete blood count (CBC) is performed using automated hematology analyzers. It is important that CBC results are comparable, reproducible, and reliable. In this study, our aim is to compare the results of Sysmex XN-1000 and Dirui BF-7200 hematology
Externí odkaz:
https://doaj.org/article/a61a93bbf34a470680b0349922a06a83
Publikováno v:
PeerJ Computer Science, Vol 10, p e1818 (2024)
Teaching computer architecture (Comp-Arch) courses in undergraduate curricula is becoming more of a challenge as most students prefer software-oriented courses. In some computer science/engineering departments, Comp-Arch courses are offered without t
Externí odkaz:
https://doaj.org/article/e62b51222c7f485e889398c60584abbd
Publikováno v:
Türk Nöroloji Dergisi, Vol 29, Iss 1, Pp 24-29 (2023)
Objective: This study aimed to determine the serum levels of neopterin, galectin-3, tissue necrosis factor alpha, and interleukin-10 (IL-10) during the interictal and attack periods of patients with migraine. It is hoped that the findings will contri
Externí odkaz:
https://doaj.org/article/baad694de1504c109a99525e82249425
Publikováno v:
Управленец, Vol 13, Iss 6, Pp 70-85 (2023)
Over the past two decades, the gaming industry has rapidly increased its popularity and gained a top spot in the entertainment sector. With this rise, customer relations and churn analysis have become even more prominent in gaming, as digital games a
Externí odkaz:
https://doaj.org/article/76a99582849847f88d64e70f1bcbf5e6
Autor:
Ashley Hertzog, Arthavan Selvanathan, Dinusha Pandithan, Won‐Tae Kim, Maina P. Kava, Avihu Boneh, David Coman, Adviye Ayper Tolun, Kaustuv Bhattacharya
Publikováno v:
JIMD Reports, Vol 63, Iss 6, Pp 568-574 (2022)
Abstract 3‐Methylglutaconyl‐CoA hydratase deficiency (MGA1) is a defect in leucine catabolism, which causes the accumulation of urinary 3‐methylglutaconate, with or without 3‐hydroxyisovalerate and 3‐methylglutarate. It is an ultra‐rare c
Externí odkaz:
https://doaj.org/article/39ec7e9c371b427494f411a4a81cdbda
Autor:
Timothy P. Newing, Jodi L. Brewster, Lucy J. Fitschen, James C. Bouwer, Nikolas P. Johnston, Haibo Yu, Gökhan Tolun
Publikováno v:
Nature Communications, Vol 13, Iss 1, Pp 1-14 (2022)
Redβ annealase catalyses single-strand annealing homologous DNA recombination. Here, the authors present a cryo-EM structure of a Redβ annealing intermediate bound to two complementary 27mer oligonucleotides.
Externí odkaz:
https://doaj.org/article/d8eae846edef420e98dca3a781c83034
Akademický článek
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Autor:
Ashley Hertzog, Arthavan Selvanathan, Rebecca Halligan, Timothy Fazio, Gerard deJong, Drago Bratkovic, Kaustuv Bhattacharya, Adviye Ayper Tolun, Bruce Bennetts, Katrina Fisk
Publikováno v:
JIMD Reports, Vol 63, Iss 4, Pp 271-275 (2022)
Abstract Ornithine transcarbamylase deficiency (OTCD) is an X‐linked urea cycle disorder characterised by reduced or absent OTC enzyme activity, resulting in the accumulation of neurotoxic ammonia. Approximately 80%–90% of the causative variants
Externí odkaz:
https://doaj.org/article/8369048c96c14402aa1d899a83ae76a9