Oligodeoxynucleotides containing unmethylated cytosine-guanine motifs are effective immunostimulants against pneumococcal meningitis in the immunocompetent and neutropenic host

Autor: Ribes, S., Zacke, L., Nessler, S., Saiepour, N., Avendaño-Guzmán, E., Ballüer, M., Hanisch, U. K., Nau, R.

Publikováno v: Journal of Neuroinflammation
Journal of Neuroinflammation, Vol 18, Iss 1, Pp 1-15 (2021)

Background Bacterial meningitis is a fatal disease with a mortality up to 30% and neurological sequelae in one fourth of survivors. Available vaccines do not fully protect against this lethal disease. Here, we report the protective effect of syntheti

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=pmid_dedup__::ea0f5e583f08101efb82fefd34cc9250
http://resolver.sub.uni-goettingen.de/purl?gs-1/17725

TLR9 agonists induced cell death in Burkitt's lymphoma cells is variable and influenced by TLR9 polymorphism

Autor: M Jordi, David Nadal, Julia Noack, Martin Hersberger, A Burch, Michele Bernasconi, D Alessi, Ludwig Zauner, Marianne Tinguely

Publikováno v: Cell death & disease
Cell Death & Disease

Toll-like receptor 9 (TLR9) triggering is a promising novel strategy to combat cancer as it induces innate and adaptive immunity responses. B-cell lymphoma is unique in this context as tumor cells express TLR9 and may harbor latent Epstein-Barr virus

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::7e6fa45f07725b802a8fa2f9853bb96e
http://www.nature.com/cddis/journal/v3/n6/full/cddis201260a.html

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Oligodeoxynucleotides containing unmethylated cytosine-guanine motifs are effective immunostimulants against pneumococcal meningitis in the immunocompetent and neutropenic host.

Autor: Ribes S; Institute of Neuropathology, University Medical Center, Georg August University Göttingen, Robert-Koch-Straße 40, D-37075, Göttingen, Germany. ribes.miravet@gmail.com., Zacke L; Institute of Neuropathology, University Medical Center, Georg August University Göttingen, Robert-Koch-Straße 40, D-37075, Göttingen, Germany., Nessler S; Institute of Neuropathology, University Medical Center, Georg August University Göttingen, Robert-Koch-Straße 40, D-37075, Göttingen, Germany., Saiepour N; Institute of Neuropathology, University Medical Center, Georg August University Göttingen, Robert-Koch-Straße 40, D-37075, Göttingen, Germany., Avendaño-Guzmán E; Institute of Neuropathology, University Medical Center, Georg August University Göttingen, Robert-Koch-Straße 40, D-37075, Göttingen, Germany., Ballüer M; Institute of Neuropathology, University Medical Center, Georg August University Göttingen, Robert-Koch-Straße 40, D-37075, Göttingen, Germany.; Department of Geriatrics, Protestant Hospital Göttingen-Weende, Göttingen, Germany., Hanisch UK; Institute of Neuropathology, University Medical Center, Georg August University Göttingen, Robert-Koch-Straße 40, D-37075, Göttingen, Germany., Nau R; Institute of Neuropathology, University Medical Center, Georg August University Göttingen, Robert-Koch-Straße 40, D-37075, Göttingen, Germany.; Department of Geriatrics, Protestant Hospital Göttingen-Weende, Göttingen, Germany.

Publikováno v: Journal of neuroinflammation [J Neuroinflammation] 2021 Feb 02; Vol. 18 (1), pp. 39. Date of Electronic Publication: 2021 Feb 02.