Zobrazeno 1 - 10
of 118
pro vyhledávání: '"Tolga Can"'
Autor:
Didem Naz Dioken, Ibrahim Ozgul, Gozde Koksal Bicakci, Kemal Gol, Tolga Can, Ayse Elif Erson-Bensan
Publikováno v:
Heliyon, Vol 9, Iss 9, Pp e20035- (2023)
Early diagnosis and therapeutic targeting are continuing challenges for gynecological cancers. Here, we focus on cancer transcriptomes and describe the differential expression of 3′UTR isoforms in patients using an algorithm to detect differential
Externí odkaz:
https://doaj.org/article/3d227d07e6f949e195c4c170b08cb7e9
Autor:
Murat Erdem, İbrahim Ozgul, Didem Naz Dioken, Irmak Gurcuoglu, Sezen Guntekin Ergun, Rengul Cetin-Atalay, Tolga Can, Ayse Elif Erson-Bensan
Publikováno v:
Scientific Reports, Vol 11, Iss 1, Pp 1-15 (2021)
Abstract Roles of HNRNPA1 are beginning to emerge in cancers; however, mechanisms causing deregulation of HNRNPA1 function remain elusive. Here, we describe an isoform switch between the 3′-UTR isoforms of HNRNPA1 in breast cancers. We show that th
Externí odkaz:
https://doaj.org/article/bd105dc456f04a9b967fd9a19f1e036d
Autor:
Gamze Ayaz, Gizem Turan, Çağla Ece Olgun, Gizem Kars, Burcu Karakaya, Kerim Yavuz, Öykü Deniz Demiralay, Tolga Can, Mesut Muyan, Pelin Yaşar
Publikováno v:
Scientific Reports, Vol 11, Iss 1, Pp 1-19 (2021)
Abstract CXXC5 is a member of the zinc-finger CXXC family proteins that interact with unmodified CpG dinucleotides through a conserved ZF-CXXC domain. CXXC5 is involved in the modulation of gene expressions that lead to alterations in diverse cellula
Externí odkaz:
https://doaj.org/article/75e2878109d14e88b1641504d87a2085
Autor:
Pelin Yaşar, Gizem Kars, Kerim Yavuz, Gamze Ayaz, Çerağ Oğuztüzün, Ecenaz Bilgen, Zeynep Suvacı, Özgül Persil Çetinkol, Tolga Can, Mesut Muyan
Publikováno v:
Scientific Reports, Vol 11, Iss 1, Pp 1-20 (2021)
Abstract CXXC5 is a member of the zinc-finger CXXC family that binds to unmethylated CpG dinucleotides. CXXC5 modulates gene expressions resulting in diverse cellular events mediated by distinct signaling pathways. However, the mechanism responsible
Externí odkaz:
https://doaj.org/article/3dfa5821e414403e9650cdc17758dc3d
Autor:
Burçak Otlu, Tolga Can
Publikováno v:
BMC Bioinformatics, Vol 20, Iss 1, Pp 1-14 (2019)
Abstract Background Next-generation sequencing (NGS) technologies have produced large volumes of genomic data. One common operation on heterogeneous genomic data is genomic interval intersection. Most of the existing tools impose restrictions such as
Externí odkaz:
https://doaj.org/article/fb2fee7b21514990928aaa20e8e72932
Publikováno v:
Neoplasia: An International Journal for Oncology Research, Vol 19, Iss 7, Pp 574-582 (2017)
Certain aspects of diagnosis, prognosis, and treatment of cancer patients are still important challenges to be addressed. Therefore, we propose a pipeline to uncover patterns of alternative polyadenylation (APA), a hidden complexity in cancer transcr
Externí odkaz:
https://doaj.org/article/26f640375975491eaa19162fb7bacf5d
Autor:
Ahmet Rasit Ozturk, Tolga Can
Publikováno v:
BMC Bioinformatics, Vol 18, Iss 1, Pp 1-9 (2017)
Abstract Background Targeted Next Generation Sequencing (NGS) assays are cost-efficient and reliable alternatives to Sanger sequencing. For sequencing of very large set of genes, the target enrichment approach is suitable. However, for smaller genomi
Externí odkaz:
https://doaj.org/article/169c4f0696014e87b54079de63fd6cfb
Autor:
Çallar, Tolga-Can, Böttger, Sven
Applications of force control and motion planning often rely on an inverse dynamics model to represent the high-dimensional dynamic behavior of robots during motion. The widespread occurrence of low-velocity, small-scale, locally isotropic motion (LI
Externí odkaz:
http://arxiv.org/abs/2211.12921
Publikováno v:
PLoS ONE, Vol 9, Iss 12, p e115445 (2014)
Sequence similarity tools, such as BLAST, seek sequences most similar to a query from a database of sequences. They return results significantly similar to the query sequence and that are typically highly similar to each other. Most sequence analysis
Externí odkaz:
https://doaj.org/article/6a1fb03b331a4e86b492e999ccc36b69
Publikováno v:
PLoS ONE, Vol 9, Iss 3, p e93341 (2014)
Transcriptome experiments are performed to assess protein abundance through mRNA expression analysis. Expression levels of genes vary depending on the experimental conditions and the cell response. Transcriptome data must be diverse and yet comparabl
Externí odkaz:
https://doaj.org/article/400b651814f04370a98ea2a5f93d0b6c