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Thermodynamic coupling of the tandem RRM domains of hnRNP A1 underlie its pleiotropic RNA binding functions.

Autor: Levengood JD; Department of Biochemistry and Biophysics, University of Pennsylvania, Philadelphia, PA 19104, USA., Potoyan D; Department of Chemistry, Iowa State University, Ames, IA 50011, USA., Penumutchu S; Department of Biochemistry and Biophysics, University of Pennsylvania, Philadelphia, PA 19104, USA., Kumar A; Department of Molecular Microbiology, Washington University School of Medicine, St. Louis, MO 63110, USA., Zhou Q; Department of Molecular Microbiology, Washington University School of Medicine, St. Louis, MO 63110, USA., Wang Y; Department of Molecular Microbiology, Washington University School of Medicine, St. Louis, MO 63110, USA.; New York University Grossman School of Medicine, New York, NY 10016, USA., Hansen AL; CCIC and Gateway NMR Facility, The Ohio State University, Columbus, OH 43210, USA., Kutluay S; Department of Molecular Microbiology, Washington University School of Medicine, St. Louis, MO 63110, USA., Roche J; Roy J. Carver Department of Biochemistry, Biophysics and Molecular Biology, Iowa State University, Ames, IA 50011, USA., Tolbert BS; Department of Biochemistry and Biophysics, University of Pennsylvania, Philadelphia, PA 19104, USA.; Howard Hughes Medical Institute, Chevy Chase, MD 20815, USA.

Publikováno v: Science advances [Sci Adv] 2024 Jul 12; Vol. 10 (28), pp. eadk6580. Date of Electronic Publication: 2024 Jul 10.

The Repurposing of Cellular Proteins during Enterovirus A71 Infection.

Autor: Abedeera SM; Department of Biochemistry and Biophysics, Perelman School of Medicine, University of Pennsylvania, Philadelphia, PA 19104, USA., Davila-Calderon J; Department of Chemistry, Case Western Reserve University, Cleveland, OH 44106, USA., Haddad C; Department of Chemistry, Case Western Reserve University, Cleveland, OH 44106, USA., Henry B; Department of Biochemistry and Biophysics, Perelman School of Medicine, University of Pennsylvania, Philadelphia, PA 19104, USA., King J; Department of Chemistry, Case Western Reserve University, Cleveland, OH 44106, USA., Penumutchu S; Department of Biochemistry and Biophysics, Perelman School of Medicine, University of Pennsylvania, Philadelphia, PA 19104, USA., Tolbert BS; Department of Biochemistry and Biophysics, Perelman School of Medicine, University of Pennsylvania, Philadelphia, PA 19104, USA.; Howard Hughes Medical Institute, Chevy Chase, MD 20815, USA.

Publikováno v: Viruses [Viruses] 2023 Dec 31; Vol. 16 (1). Date of Electronic Publication: 2023 Dec 31.

Influenza virus mRNAs encode determinants for nuclear export via the cellular TREX-2 complex.

Autor: Bhat P; Department of Cell Biology, University of Texas Southwestern Medical Center, Dallas, TX, 75390, USA., Aksenova V; Division of Molecular and Cellular Biology, National Institute of Child Health and Human Development, National Institutes of Health, Bethesda, MD, 20892, USA., Gazzara M; Department of Biochemistry and Biophysics, University of Pennsylvania, Philadelphia, PA, 19104, USA., Rex EA; Department of Cell Biology, University of Texas Southwestern Medical Center, Dallas, TX, 75390, USA., Aslam S; Department of Microbiology, Icahn School of Medicine at Mount Sinai, New York, NY, 10029, USA.; Global Health and Emerging Pathogens Institute, Icahn School of Medicine at Mount Sinai, New York, NY, 10029, USA., Haddad C; Department of Chemistry, Case Western Reserve University, Cleveland, OH, 44106, USA., Gao S; Department of Cell Biology, University of Texas Southwestern Medical Center, Dallas, TX, 75390, USA., Esparza M; Department of Cell Biology, University of Texas Southwestern Medical Center, Dallas, TX, 75390, USA., Cagatay T; Department of Cell Biology, University of Texas Southwestern Medical Center, Dallas, TX, 75390, USA., Batten K; Department of Cell Biology, University of Texas Southwestern Medical Center, Dallas, TX, 75390, USA., El Zahed SS; Department of Microbiology, Icahn School of Medicine at Mount Sinai, New York, NY, 10029, USA.; Global Health and Emerging Pathogens Institute, Icahn School of Medicine at Mount Sinai, New York, NY, 10029, USA., Arnaoutov A; Division of Molecular and Cellular Biology, National Institute of Child Health and Human Development, National Institutes of Health, Bethesda, MD, 20892, USA., Zhong H; Department of Biological Sciences, Hunter College, New York, NY, 10065, USA., Shay JW; Department of Cell Biology, University of Texas Southwestern Medical Center, Dallas, TX, 75390, USA., Tolbert BS; Department of Chemistry, Case Western Reserve University, Cleveland, OH, 44106, USA., Dasso M; Division of Molecular and Cellular Biology, National Institute of Child Health and Human Development, National Institutes of Health, Bethesda, MD, 20892, USA., Lynch KW; Department of Biochemistry and Biophysics, University of Pennsylvania, Philadelphia, PA, 19104, USA., García-Sastre A; Department of Microbiology, Icahn School of Medicine at Mount Sinai, New York, NY, 10029, USA.; Global Health and Emerging Pathogens Institute, Icahn School of Medicine at Mount Sinai, New York, NY, 10029, USA.; Department of Medicine, Division of Infectious Diseases, Icahn School of Medicine at Mount Sinai, New York, NY, 10029, USA.; Department of Pathology, Molecular and Cell-Based Medicine, Icahn School of Medicine at Mount Sinai, New York, NY, 10029, USA.; The Tisch Cancer Institute, Icahn School of Medicine at Mount Sinai, New York, NY, 10029, USA., Fontoura BMA; Department of Cell Biology, University of Texas Southwestern Medical Center, Dallas, TX, 75390, USA. beatriz.fontoura@utsouthwestern.edu.

Publikováno v: Nature communications [Nat Commun] 2023 Apr 21; Vol. 14 (1), pp. 2304. Date of Electronic Publication: 2023 Apr 21.

Biophysical Analysis of Small Molecule Binding to Viral RNA Structures.

Autor: Chiu LY; Department of Chemistry, Case Western Reserve University, Cleveland, OH, USA., Davila-Calderon J; Department of Chemistry, Case Western Reserve University, Cleveland, OH, USA., Cai Z; Department of Chemistry, Duke University, Durham, NC, USA., Tolbert BS; Department of Chemistry, Case Western Reserve University, Cleveland, OH, USA. bst18@case.edu.

Publikováno v: Methods in molecular biology (Clifton, N.J.) [Methods Mol Biol] 2023; Vol. 2570, pp. 205-222.