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CLSTN3β enforces adipocyte multilocularity to facilitate lipid utilization.

Autor: Qian, Kevin, Tol, Marcus J., Wu, Jin, Uchiyama, Lauren F., Xiao, Xu, Cui, Liujuan, Bedard, Alexander H., Weston, Thomas A., Rajendran, Pradeep S., Vergnes, Laurent, Shimanaka, Yuta, Yin, Yesheng, Jami-Alahmadi, Yasaman, Cohn, Whitaker, Bajar, Bryce T., Lin, Chia-Ho, Jin, Benita, DeNardo, Laura A., Black, Douglas L., Whitelegge, Julian P.

Publikováno v: Nature; Jan2023, Vol. 613 Issue 7942, p160-168, 9p

PPARγ-dependent Remodeling of Translational Machinery in Adipose Progenitors is Impaired in Obesity

Autor: De Siqueira, Mirian Krystel, Li, Gaoyan, Zhao, Yutian, Wang, Siqi, Ahn, In Sook, Tamboline, Mikayla, Hildreth, Andrew D., Larios, Jakeline, Schcolnik-Cabrera, Alejandro, Nouhi, Zaynab, Zhang, Zhengyi, Tol, Marcus J., Pandey, Vijaya, Xu, Shili, O’Sullivan, Timothy E., Mack, Julia J., Tontonoz, Peter J., Sallam, Tamer, Wohlschlegel, James A., Hulea, Laura, Xiao, Xinshu Grace, Yang, Xia, Villanueva, Claudio J.

Publikováno v: Cell Reports; 20240101, Issue: Preprints

Cholesterol binding to VCAM-1 promotes vascular inflammation.

Autor: Kennelly JP; Department of Pathology and Laboratory Medicine, University of California, Los Angeles (UCLA); Los Angeles, CA 90095, USA.; Department of Biological Chemistry, UCLA, Los Angeles, CA 90095, USA.; These authors contributed equally., Xiao X; Department of Pathology and Laboratory Medicine, University of California, Los Angeles (UCLA); Los Angeles, CA 90095, USA.; Department of Biological Chemistry, UCLA, Los Angeles, CA 90095, USA.; These authors contributed equally., Gao Y; Department of Pathology and Laboratory Medicine, University of California, Los Angeles (UCLA); Los Angeles, CA 90095, USA.; Department of Biological Chemistry, UCLA, Los Angeles, CA 90095, USA., Kim S; Department of Biochemistry and Molecular Biology, Seoul National University College of Medicine, Seoul, 03080, Korea., Hong SG; Molecular Biology Institute, UCLA, Los Angeles, CA 90095, USA.; Department of Medicine, Division of Cardiology, UCLA, Los Angeles, CA, USA., Villanueva M; Department of Biological Chemistry, UCLA, Los Angeles, CA 90095, USA., Ferrari A; Department of Pathology and Laboratory Medicine, University of California, Los Angeles (UCLA); Los Angeles, CA 90095, USA.; Department of Biological Chemistry, UCLA, Los Angeles, CA 90095, USA., Vanharanta L; Department of Anatomy and Stem Cells and Metabolism Research Program, Faculty of Medicine, University of Helsinki, 00290 Helsinki, Finland.; Minerva Foundation Institute for Medical Research, 00290 Helsinki, Finland., Nguyen A; Department of Pathology and Laboratory Medicine, University of California, Los Angeles (UCLA); Los Angeles, CA 90095, USA.; Department of Biological Chemistry, UCLA, Los Angeles, CA 90095, USA.; Vatche and Tamar Manoukian Division of Digestive Diseases, Department of Medicine David Geffen School of Medicine, University of California, Los Angeles (UCLA), Los Angeles, CA, USA., Nagari RT; Department of Pathology and Laboratory Medicine, University of California, Los Angeles (UCLA); Los Angeles, CA 90095, USA.; Department of Biological Chemistry, UCLA, Los Angeles, CA 90095, USA., Burton NR; Department of Biological Chemistry, UCLA, Los Angeles, CA 90095, USA.; Department of Chemistry and Biochemistry, UCLA, Los Angeles, California 90095, United States., Tol MJ; Department of Pathology and Laboratory Medicine, University of California, Los Angeles (UCLA); Los Angeles, CA 90095, USA.; Department of Biological Chemistry, UCLA, Los Angeles, CA 90095, USA., Becker AP; Department of Biological Chemistry, UCLA, Los Angeles, CA 90095, USA., Lee MJ; Department of Biochemistry and Molecular Biology, Seoul National University College of Medicine, Seoul, 03080, Korea., Ikonen E; Department of Anatomy and Stem Cells and Metabolism Research Program, Faculty of Medicine, University of Helsinki, 00290 Helsinki, Finland.; Minerva Foundation Institute for Medical Research, 00290 Helsinki, Finland., Backus KM; Department of Biological Chemistry, UCLA, Los Angeles, CA 90095, USA.; Department of Chemistry and Biochemistry, UCLA, Los Angeles, California 90095, United States.; DOE Institute for Genomics and Proteomics, UCLA, Los Angeles, California 90095, United States.; Jonsson Comprehensive Cancer Center, UCLA, Los Angeles, California 90095, United States.; Eli and Edythe Broad Center of Regenerative Medicine and Stem Cell Research, UCLA, Los Angeles, California 90095, United States., Mack JJ; Molecular Biology Institute, UCLA, Los Angeles, CA 90095, USA.; Department of Medicine, Division of Cardiology, UCLA, Los Angeles, CA, USA., Tontonoz P; Department of Pathology and Laboratory Medicine, University of California, Los Angeles (UCLA); Los Angeles, CA 90095, USA.; Department of Biological Chemistry, UCLA, Los Angeles, CA 90095, USA.

Publikováno v: BioRxiv : the preprint server for biology [bioRxiv] 2024 Sep 18. Date of Electronic Publication: 2024 Sep 18.

Measuring Mitochondrial Uncoupling in Mouse Primary Brown Adipocytes Differentiated Ex Vivo.

Autor: Veliova M; Division of Endocrinology, Department of Medicine, David Geffen School of Medicine at UCLA, Los Angeles, CA, USA.; Department of Molecular and Medical Pharmacology, David Geffen School of Medicine at UCLA, Los Angeles, CA, USA., Tol MJ; Department of Pathology and Laboratory Medicine, David Geffen School of Medicine at UCLA, Los Angeles, CA, USA.; Department of Biological Chemistry, David Geffen School of Medicine at UCLA, Los Angeles, CA, USA.; Molecular Biology Institute, University of California, Los Angeles, CA, USA., Tontonoz P; Department of Pathology and Laboratory Medicine, David Geffen School of Medicine at UCLA, Los Angeles, CA, USA.; Department of Biological Chemistry, David Geffen School of Medicine at UCLA, Los Angeles, CA, USA.; Molecular Biology Institute, University of California, Los Angeles, CA, USA., Shirihai OS; Division of Endocrinology, Department of Medicine, David Geffen School of Medicine at UCLA, Los Angeles, CA, USA.; Department of Molecular and Medical Pharmacology, David Geffen School of Medicine at UCLA, Los Angeles, CA, USA., Liesa M; Division of Endocrinology, Department of Medicine, David Geffen School of Medicine at UCLA, Los Angeles, CA, USA. mlrbmc@ibmb.csic.es.; Department of Molecular and Medical Pharmacology, David Geffen School of Medicine at UCLA, Los Angeles, CA, USA. mlrbmc@ibmb.csic.es.; Molecular Biology Institute, University of California, Los Angeles, CA, USA. mlrbmc@ibmb.csic.es.; Institut de Biologia Molecular de Barcelona, IBMB, CSIC, Barcelona, Catalonia, Spain. mlrbmc@ibmb.csic.es.

Publikováno v: Methods in molecular biology (Clifton, N.J.) [Methods Mol Biol] 2023; Vol. 2662, pp. 53-65.