Zobrazeno 1 - 10
of 149
pro vyhledávání: '"Tokuzo Arao"'
Autor:
Yosuke Tanaka, Kazuhiko Aoyagi, Keiko Minashi, Rie Komatsuzaki, Masayuki Komatsu, Fumiko Chiwaki, Masashi Tamaoki, Takao Nishimura, Naoki Takahashi, Ichiro Oda, Yuji Tachimori, Tokuzo Arao, Kazuto Nishio, Shigehisa Kitano, Kenta Narumi, Kazunori Aoki, Satoshi Fujii, Atsushi Ochiai, Teruhiko Yoshida, Manabu Muto, Yasuhide Yamada, Hiroki Sasaki
Publikováno v:
PLoS ONE, Vol 10, Iss 12, p e0143804 (2015)
Definitive chemoradiotherapy (CRT) is a less invasive therapy for esophageal squamous cell carcinoma (ESCC). Five-year survival rate of locally advanced ESCC patients by definitive CRT were 37%. We previously reported that tumor-specific cytotoxic T-
Externí odkaz:
https://doaj.org/article/17f86009996841d4a7eeb10a20f4fbdf
Autor:
Hyonchol Kim, Hideyuki Terazono, Yoshiyasu Nakamura, Kazuko Sakai, Akihiro Hattori, Masao Odaka, Mathias Girault, Tokuzo Arao, Kazuto Nishio, Yohei Miyagi, Kenji Yasuda
Publikováno v:
PLoS ONE, Vol 9, Iss 8, p e104372 (2014)
An on-chip multi-imaging flow cytometry system has been developed to obtain morphometric parameters of cell clusters such as cell number, perimeter, total cross-sectional area, number of nuclei and size of clusters as "imaging biomarkers", with simul
Externí odkaz:
https://doaj.org/article/54dab818f33f42f987ae8c8537ed670d
Autor:
Issei Kurahashi, Yoshihiko Fujita, Tokuzo Arao, Takayasu Kurata, Yasuhiro Koh, Kazuko Sakai, Koji Matsumoto, Maki Tanioka, Koji Takeda, Yuichi Takiguchi, Nobuyuki Yamamoto, Asuka Tsuya, Nobuaki Matsubara, Hirofumi Mukai, Hironobu Minami, Naoko Chayahara, Yasuhiro Yamanaka, Keisuke Miwa, Shin Takahashi, Shunji Takahashi, Kazuhiko Nakagawa, Kazuto Nishio
Publikováno v:
PLoS ONE, Vol 8, Iss 5, p e63249 (2013)
BACKGROUND: The biological basis for cancer of unknown primary (CUP) at the molecular level remains largely unknown, with no evidence of whether a common biological entity exists. Here, we assessed the possibility of identifying a common diagnostic b
Externí odkaz:
https://doaj.org/article/ee6c53410c01476ebd81ae0d1354c742
Autor:
Kaoru Tanaka, Tokuzo Arao, Daisuke Tamura, Keiichi Aomatsu, Kazuyuki Furuta, Kazuko Matsumoto, Hiroyasu Kaneda, Kanae Kudo, Yoshihiko Fujita, Hideharu Kimura, Kazuyoshi Yanagihara, Yasuhide Yamada, Isamu Okamoto, Kazuhiko Nakagawa, Kazuto Nishio
Publikováno v:
PLoS ONE, Vol 7, Iss 1, p e27922 (2012)
SRPX2 (Sushi repeat-containing protein, X-linked 2) has recently emerged as a multifunctional protein that is involved in seizure disorders, angiogenesis and cellular adhesion. Here, we analyzed this protein biochemically. SRPX2 protein was secreted
Externí odkaz:
https://doaj.org/article/3fa9c2af71e94becb7d16390f15e752c
Autor:
Keisuke Tabara, Rina Kanda, Kahori Sonoda, Takuya Kubo, Yuichi Murakami, Akihiko Kawahara, Koichi Azuma, Hideyuki Abe, Masayoshi Kage, Aki Yoshinaga, Tomoko Tahira, Kenshi Hayashi, Tokuzo Arao, Kazuto Nishio, Rafael Rosell, Michihiko Kuwano, Mayumi Ono
Publikováno v:
PLoS ONE, Vol 7, Iss 7, p e41017 (2012)
Non-small-cell lung cancer harboring epidermal growth factor receptor (EGFR) mutations attains a meaningful response to EGFR-tyrosine kinase inhibitors (TKIs). However, acquired resistance to EGFR-TKIs could affect long-term outcome in almost all pat
Externí odkaz:
https://doaj.org/article/3351c64353dc44c3acfa873fa02ffebb
Autor:
Hiroki Ureshino, Yuichi Murakami, Kosuke Watari, Hiroto Izumi, Akihiko Kawahara, Masayoshi Kage, Tokuzo Arao, Kazuto Nishio, Kazuyoshi Yanagihara, Hisafumi Kinoshita, Michihiko Kuwano, Mayumi Ono
Publikováno v:
PLoS ONE, Vol 7, Iss 7, p e41312 (2012)
Our recent study demonstrated that higher expression of N-myc downregulated gene 1 (NDRG1) is closely correlated with poor prognosis in gastric cancer patients. In this study, we asked whether NDRG1 has pivotal roles in malignant progression includin
Externí odkaz:
https://doaj.org/article/a71589f889aa4653bf0cbe33d2dc5e99
Autor:
Kazuhiko Nakagawa, Kazuto Nishio, Kazuyoshi Yanagihara, Kazuko Sakai, Haruka Yamaguchi, Erina Hatashita, Kiyoko Kuwata, Tokuzo Arao, Isamu Okamoto, Wataru Okamoto
PDF file, 123KB, Effects of crizotinib (50 nM) on MET, AKT, ERK and STAT3 phosphorylation in gastric cancer cells with MET amplification.
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::2d8ea4e0d578133e7f6617422a54bb36
https://doi.org/10.1158/1535-7163.22497654.v1
https://doi.org/10.1158/1535-7163.22497654.v1
Autor:
Kazuhiko Nakagawa, Kazuto Nishio, Kazuyoshi Yanagihara, Kazuko Sakai, Haruka Yamaguchi, Erina Hatashita, Kiyoko Kuwata, Tokuzo Arao, Isamu Okamoto, Wataru Okamoto
PDF file, 138KB, Effects of crizotinib on cell cycle distribution in gastric cancer cells with MET amplification.
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::8bc7569810b4b6f5de26c2815c2dbd38
https://doi.org/10.1158/1535-7163.22497651.v1
https://doi.org/10.1158/1535-7163.22497651.v1
Autor:
Kazuhiko Nakagawa, Kazuto Nishio, Kazuyoshi Yanagihara, Kazuko Sakai, Haruka Yamaguchi, Erina Hatashita, Kiyoko Kuwata, Tokuzo Arao, Isamu Okamoto, Wataru Okamoto
PDF file, 126KB, Effects of crizotinib on the growth of gastric cancer cells in vivo.
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::8c3cb0618b6e3dcc8f6731f067b03a1f
https://doi.org/10.1158/1535-7163.22497648.v1
https://doi.org/10.1158/1535-7163.22497648.v1
Autor:
Kazuhiko Nakagawa, Kazuto Nishio, Kazuyoshi Yanagihara, Kazuko Sakai, Haruka Yamaguchi, Erina Hatashita, Kiyoko Kuwata, Tokuzo Arao, Isamu Okamoto, Wataru Okamoto
PDF file, 94KB.
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::3cb22fea913a80cefc7315d35f62d1db
https://doi.org/10.1158/1535-7163.22497645
https://doi.org/10.1158/1535-7163.22497645