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pro vyhledávání: '"Tokurou Kobayashi"'
Autor:
Tomoya Kagawa, Tokurou Kobayashi, Shingo Kuroda, Masashi Sakaki, Yuhei Sano, Takuya Saiki, Emiko Koumura, Yukio Shimasaki, Kohei Shimizu, Minoru Itou, Kumi Matsuno, Masako Aso
Publikováno v:
Clinical Drug Investigation. 38:1041-1051
Imarikiren hydrochloride (TAK-272; SCO-272) is a novel direct renin inhibitor. The objective of this study was to determine the effects of renal impairment (RI) or hepatic impairment (HI) on the pharmacokinetics and safety of imarikiren. This phase I