Zobrazeno 1 - 9
of 9
pro vyhledávání: '"Tokiko Hatano"'
Autor:
Yuto Takebayashi, Maiko Kitazawa, Yuri Hotta, Heii Arai, Motoyuki Higa, Ryo Hanzawa, Tohru Ohnuma, Nobuto Shibata, Tokiko Hatano, Hajime Baba, Hitoshi Maeshima
Publikováno v:
Progress in Neuro-Psychopharmacology and Biological Psychiatry. 35:1965-1968
Disrupted glutamatergic neurotransmission may be a pathophysiological feature in the brains from patients with schizophrenia, and glutamatergic amino acids including D-serine have been found to be involved in pathophysiology. Endogenous and exogenous
Autor:
Maiko Kitazawa, Tokiko Hatano, Yasuhito Nagai, Tohru Ohnuma, Hajime Baba, Nobuto Shibata, Yuri Hotta, Hitoshi Maeshima, Yuto Takebayashi, Heii Arai, Ryo Hanzawa
Publikováno v:
Psychiatry and Clinical Neurosciences. 65:39-46
Aims: Schizophrenia is a major psychiatric disorder with complex genetic, environmental, and psychological causes, and oxidative stress may be involved in the pathogenesis of the disease. Glutathione (GSH), one of the main cellular non-protein antiox
Autor:
Yasuhito Nagai, Jun Karibe, Nobuto Shibata, Tokiko Hatano, Tohru Ohnuma, Hitoshi Maeshima, Ryo Hanzawa, Hajime Baba, Heii Arai
Publikováno v:
Neuroscience Letters. 463:223-227
Glutamatergic dysfunction may be a pathophysiological feature in the brains of schizophrenic patients. In addition to glutamate receptors, excitatory amino acid transporters (EAATs) have received much attention because they directly affect glutamater
Autor:
Heii Arai, Nobuto Shibata, Hitoshi Maeshima, Tokiko Hatano, Hajime Baba, Tohru Ohnuma, Ryo Hanzawa
Publikováno v:
Progress in Neuro-Psychopharmacology and Biological Psychiatry. 33:511-518
Differences in the levels of the glutamate-related amino acids glycine and serine in brain/plasma between schizophrenic patients and normal subjects and changes in the plasma concentrations of these amino acids according to the clinical course have b
Autor:
Heii Arai, Nobuto Shibata, Tokiko Hatano, Sawako Abe, Tohru Ohnuma, Sayaka Kida, Toshihito Suzuki, Hitoshi Maeshima, Yoshie Sakai, Ryo Hanzawa
Publikováno v:
Progress in Neuro-Psychopharmacology and Biological Psychiatry. 32:1905-1912
Objectives Based on the hypothesis of NMDA receptor hypofunction in schizophrenia, plasma glycine, l -serine, and d -serine levels have been studied, since they could serve as biological markers. However, changes over time in the levels of these amin
Autor:
Nobuto Shibata, Maiko Kitazawa, Tokiko Hatano, Yuri Hotta, Heii Arai, Toshihito Suzuki, Hajime Baba, Tohru Ohnuma, Yuto Takebayashi, Motoyuki Higa, Ryo Hanzawa, Hitoshi Maeshima
Publikováno v:
Progress in neuro-psychopharmacologybiological psychiatry. 35(2)
Treating the 20-30% of patients with schizophrenia whose symptoms are resistant to antipsychotic treatment, a condition known as treatment-resistant schizophrenia (TRS), can be problematic. Recently, an association between Disrupted-in-Schizophrenia-
Autor:
Ryo, Hanzawa, Tohru, Ohnuma, Yasuhito, Nagai, Nobuto, Shibata, Hitoshi, Maeshima, Hajime, Baba, Tokiko, Hatano, Yuto, Takebayashi, Yuri, Hotta, Maiko, Kitazawa, Heii, Arai
Publikováno v:
Psychiatry and clinical neurosciences. 65(1)
Schizophrenia is a major psychiatric disorder with complex genetic, environmental, and psychological causes, and oxidative stress may be involved in the pathogenesis of the disease. Glutathione (GSH), one of the main cellular non-protein antioxidants
Autor:
Tohru Ohnuma, Ryo Hanzawa, Heii Arai, Nobuto Shibata, Hitoshi Maeshima, Toshihito Suzuki, Masayuki Higa, Tokiko Hatano, Yoshie Sakai
Publikováno v:
Neuroscience letters. 469(1)
Antipsychotic-induced extrapyramidal symptoms (AIEPSs) are commonly recognized side effects of typical 1st generation antipsychotics, and considerable variability is seen in the susceptibility of individual patients to AIEPSs. Regulator of G-protein
Autor:
Tokiko Hatano, Yoshie Sakai, Heii Arai, Nobuto Shibata, Toshihito Suzuki, Tohru Ohnuma, Hitoshi Maeshima, Ryo Hanzawa
Publikováno v:
Psychiatry research. 177(1-2)
Since oral administration of d -alanine, an agonist that binds to the glycine site of N-methyl- d -aspartate (NMDA) receptors, improves the positive and cognitive symptoms of patients with schizophrenia, measurement of endogenous plasma alanine level