Zobrazeno 1 - 4
of 4
pro vyhledávání: '"Tokie Totsu"'
Autor:
Yoshiro Yamamura, Naoto Morimura, Takuji Suzuki, Hitoshi Tsuyuzaki, Eisei Noiri, Kensuke Nakamura, Naoki Yahagi, Kent Doi, Tokie Totsu, Yoshiomi Kusakabe, Kanji Uchida, Kyungho Chang, Takahiro Hiruma, Bruce C. Trapnell, Yoshitsugu Yamada, Susumu Nakajima, Shigeki Morita
Publikováno v:
American Journal of Respiratory Cell and Molecular Biology. 59:45-55
IFN-β is reported to improve survival in patients with acute respiratory distress syndrome (ARDS), possibly by preventing sepsis-induced immunosuppression, but its therapeutic nature in ARDS pathogenesis is poorly understood. We investigated the the
Early-phase Innate Immune Suppression in Murine Severe Sepsis Is Restored with Systemic Interferon-β
Autor:
Hitoshi Tsuyuzaki, Kyoko Hasegawa, Takahiro Hiruma, Kanji Uchida, Yoshitsugu Yamada, Yoshiro Yamamura, Yuho Tamai, Yoshiomi Kusakabe, Kyungho Chang, Tokie Totsu
Publikováno v:
Anesthesiology. 129(1)
Background Sepsis is a leading cause of death in the intensive care unit. Immune modulatory therapy targeting sepsis-associated proinflammatory responses has not shown survival benefit. Here, the authors evaluated innate immunity at the early stage o
Autor:
Kanji Uchida, Yoko Suzuki, Bruce C. Trapnell, Tokie Totsu, Takahiro Hiruma, Brenna Carey, Yoshiomi Kusakabe, Takuji Suzuki, Yoshitsugu Yamada
Publikováno v:
Journal of Immunological Methods. 413:1-11
Impaired signaling by granulocyte/macrophage-colony stimulating factor (GM-CSF) drives the pathogenesis of two diseases (autoimmune and hereditary pulmonary alveolar proteinosis (PAP)) representing over ninety percent of patients who develop PAP synd
Autor:
Kazuo Kamikawa, Masao Hirota, Shiro Kanegasaki, Koh Nakata, Tokie Totsu, Fusayo Adachi, Junichi Watanabe
Publikováno v:
Journal of Infection and Chemotherapy. 7:16-21
The bactericidal activity of two new quinolones, grepafloxacin and levofloxacin, against five strains of Mycobacterium avium was investigated in vitro. The minimum inhibitory concentrations (MICs) of these two quinolones, determined by the broth micr