Mammalian SWI/SNF chromatin remodeling complexes promote tyrosine kinase inhibitor resistance in EGFR-mutant lung cancer.

Autor: de Miguel FJ; Yale Cancer Center, New Haven, CT 06520, USA., Gentile C; Department of Pediatric Oncology, Dana-Farber Cancer Institute and Harvard Medical School, Boston, MA 02215, USA; Broad Institute of MIT and Harvard, Cambridge, MA 02142, USA., Feng WW; Department of Medical Oncology, Dana-Farber Cancer Institute and Harvard Medical School, Boston, MA, USA., Silva SJ; Department of Pathology, Yale School of Medicine, Yale University, New Haven, CT 06510, USA., Sankar A; Department of Pediatric Oncology, Dana-Farber Cancer Institute and Harvard Medical School, Boston, MA 02215, USA; Broad Institute of MIT and Harvard, Cambridge, MA 02142, USA., Exposito F; Yale Cancer Center, New Haven, CT 06520, USA., Cai WL; Department of Pathology, Yale School of Medicine, Yale University, New Haven, CT 06510, USA., Melnick MA; Yale Cancer Center, New Haven, CT 06520, USA., Robles-Oteiza C; Department of Immunobiology, Yale School of Medicine, Yale University, New Haven, CT 06510, USA., Hinkley MM; Department of Pediatric Oncology, Dana-Farber Cancer Institute and Harvard Medical School, Boston, MA 02215, USA; Broad Institute of MIT and Harvard, Cambridge, MA 02142, USA., Tsai JA; Department of Medical Oncology, Dana-Farber Cancer Institute and Harvard Medical School, Boston, MA, USA., Hartley AV; Department of Medical Oncology, Dana-Farber Cancer Institute and Harvard Medical School, Boston, MA, USA., Wei J; Department of Immunobiology, Yale School of Medicine, Yale University, New Haven, CT 06510, USA; Department of Laboratory Medicine, Yale School of Medicine, Yale University, New Haven, CT 06510, USA., Wurtz A; Yale Cancer Center, New Haven, CT 06520, USA., Li F; Yale Center for Analytical Sciences, Yale School of Public Health, Laboratory of Epidemiology and Public Health, 60 College St, New Haven, CT 06510, USA., Toki MI; Yale Cancer Center, New Haven, CT 06520, USA; Department of Pathology, Yale School of Medicine, Yale University, New Haven, CT 06510, USA., Rimm DL; Yale Cancer Center, New Haven, CT 06520, USA; Department of Pathology, Yale School of Medicine, Yale University, New Haven, CT 06510, USA; Department of Medicine (Section of Medical Oncology), Yale School of Medicine, Yale University, New Haven, CT 06510, USA., Homer R; Yale Cancer Center, New Haven, CT 06520, USA; Department of Pathology, Yale School of Medicine, Yale University, New Haven, CT 06510, USA., Wilen CB; Department of Immunobiology, Yale School of Medicine, Yale University, New Haven, CT 06510, USA; Department of Laboratory Medicine, Yale School of Medicine, Yale University, New Haven, CT 06510, USA., Xiao AZ; Department of Genetics, Yale School of Medicine, Yale University, New Haven, CT 06510, USA; Yale Stem Cell Center, Yale School of Medicine, Yale University, New Haven, CT 06510, USA., Qi J; Department of Cancer Biology, Dana-Farber Cancer Institute, Boston, MA, USA., Yan Q; Yale Cancer Center, New Haven, CT 06520, USA; Department of Pathology, Yale School of Medicine, Yale University, New Haven, CT 06510, USA; Yale Stem Cell Center, Yale School of Medicine, Yale University, New Haven, CT 06510, USA., Nguyen DX; Yale Cancer Center, New Haven, CT 06520, USA; Department of Pathology, Yale School of Medicine, Yale University, New Haven, CT 06510, USA; Department of Medicine (Section of Medical Oncology), Yale School of Medicine, Yale University, New Haven, CT 06510, USA; Yale Stem Cell Center, Yale School of Medicine, Yale University, New Haven, CT 06510, USA., Jänne PA; Department of Medical Oncology, Dana-Farber Cancer Institute and Harvard Medical School, Boston, MA, USA., Kadoch C; Department of Pediatric Oncology, Dana-Farber Cancer Institute and Harvard Medical School, Boston, MA 02215, USA; Broad Institute of MIT and Harvard, Cambridge, MA 02142, USA; Howard Hughes Medical Institute, Chevy Chase, MD 20815, USA. Electronic address: cigall_kadoch@dfci.harvard.edu., Politi KA; Yale Cancer Center, New Haven, CT 06520, USA; Department of Pathology, Yale School of Medicine, Yale University, New Haven, CT 06510, USA; Department of Medicine (Section of Medical Oncology), Yale School of Medicine, Yale University, New Haven, CT 06510, USA; Yale Stem Cell Center, Yale School of Medicine, Yale University, New Haven, CT 06510, USA. Electronic address: katerina.politi@yale.edu.

Publikováno v: Cancer cell [Cancer Cell] 2023 Aug 14; Vol. 41 (8), pp. 1516-1534.e9. Date of Electronic Publication: 2023 Aug 03.

Biomarker Discovery in Patients with Immunotherapy-Treated Melanoma with Imaging Mass Cytometry.

Autor: Martinez-Morilla S; Department of Pathology, Yale School of Medicine, New Haven, Connecticut., Villarroel-Espindola F; Department of Pathology, Yale School of Medicine, New Haven, Connecticut., Wong PF; Department of Pathology, Yale School of Medicine, New Haven, Connecticut., Toki MI; Department of Pathology, Yale School of Medicine, New Haven, Connecticut., Aung TN; Department of Pathology, Yale School of Medicine, New Haven, Connecticut., Pelekanou V; Department of Pathology, Yale School of Medicine, New Haven, Connecticut., Bourke-Martin B; Navigate BioPharma Services, Inc., Carlsbad, California., Schalper KA; Department of Pathology, Yale School of Medicine, New Haven, Connecticut., Kluger HM; Section of Medical Oncology, Department of Internal Medicine, Yale School of Medicine, New Haven, Connecticut., Rimm DL; Department of Pathology, Yale School of Medicine, New Haven, Connecticut. david.rimm@yale.edu.; Section of Medical Oncology, Department of Internal Medicine, Yale School of Medicine, New Haven, Connecticut.

Publikováno v: Clinical cancer research : an official journal of the American Association for Cancer Research [Clin Cancer Res] 2021 Apr 01; Vol. 27 (7), pp. 1987-1996. Date of Electronic Publication: 2021 Jan 27.

Benign lymph node microenvironment is associated with response to immunotherapy.

Autor: Toki MI; Department of Pathology, Yale University School of Medicine, New Haven, CT 06510, USA., Kumar D; Department of Pathology, Yale University School of Medicine, New Haven, CT 06510, USA., Ahmed FS; Department of Pathology, Yale University School of Medicine, New Haven, CT 06510, USA., Rimm DL; Department of Pathology, Yale University School of Medicine, New Haven, CT 06510, USA.; Department of Medicine, Yale University School of Medicine, New Haven, CT 06510, USA., Xu ML; Department of Pathology, Yale University School of Medicine, New Haven, CT 06510, USA.

Publikováno v: Precision clinical medicine [Precis Clin Med] 2020 Mar; Vol. 3 (1), pp. 44-53. Date of Electronic Publication: 2020 Feb 12.

Immune Checkpoint Inhibitor-Associated Pericarditis.

Autor: Altan M; Section of Medical Oncology, Yale School of Medicine, New Haven, Connecticut; Department of Thoracic/Head & Neck Medical Oncology, The University of Texas MD Anderson Cancer Center, Houston, Texas. Electronic address: maltan@mdanderson.org., Toki MI; Department of Pathology, Yale School of Medicine, New Haven, Connecticut., Gettinger SN; Section of Medical Oncology, Yale School of Medicine, New Haven, Connecticut., Carvajal-Hausdorf DE; Department of Pathology, Yale School of Medicine, New Haven, Connecticut; Anatomic Pathology, Clinica Alemana-Facultad de Medicina Universidad de Desarrollo, Vitacura, Santiago, Chile., Zugazagoitia J; Department of Pathology, Yale School of Medicine, New Haven, Connecticut., Sinard JH; Department of Pathology, Yale School of Medicine, New Haven, Connecticut., Herbst RS; Section of Medical Oncology, Yale School of Medicine, New Haven, Connecticut., Rimm DL; Section of Medical Oncology, Yale School of Medicine, New Haven, Connecticut; Department of Pathology, Yale School of Medicine, New Haven, Connecticut.

Publikováno v: Journal of thoracic oncology : official publication of the International Association for the Study of Lung Cancer [J Thorac Oncol] 2019 Jun; Vol. 14 (6), pp. 1102-1108. Date of Electronic Publication: 2019 Mar 07.

Association of B7-H4, PD-L1, and tumor infiltrating lymphocytes with outcomes in breast cancer.

Autor: Altan M; 1Section of Medical Oncology, Yale School of Medicine, New Haven, CT USA.; 2Department of Thoracic/Head & Neck Medical Oncology, The University of Texas MD Anderson Cancer Center, Houston, TX USA., Kidwell KM; 3Department of Biostatistics, School of Public Health, University of Michigan, Ann Arbor, MI USA.; 4Breast Oncology Program, University of Michigan Comprehensive Cancer Center, Ann Arbor, MI USA., Pelekanou V; 5Department of Pathology, Yale School of Medicine, New Haven, CT USA., Carvajal-Hausdorf DE; 5Department of Pathology, Yale School of Medicine, New Haven, CT USA.; 6Anatomic Pathology, Clinica Alemana-Facultad de Medicina Universidad de Desarrollo, Vitacura, Santiago Chile., Schalper KA; 1Section of Medical Oncology, Yale School of Medicine, New Haven, CT USA.; 5Department of Pathology, Yale School of Medicine, New Haven, CT USA., Toki MI; 5Department of Pathology, Yale School of Medicine, New Haven, CT USA., Thomas DG; 4Breast Oncology Program, University of Michigan Comprehensive Cancer Center, Ann Arbor, MI USA., Sabel MS; 4Breast Oncology Program, University of Michigan Comprehensive Cancer Center, Ann Arbor, MI USA., Hayes DF; 4Breast Oncology Program, University of Michigan Comprehensive Cancer Center, Ann Arbor, MI USA., Rimm DL; 1Section of Medical Oncology, Yale School of Medicine, New Haven, CT USA.; 5Department of Pathology, Yale School of Medicine, New Haven, CT USA.

Publikováno v: NPJ breast cancer [NPJ Breast Cancer] 2018 Dec 10; Vol. 4, pp. 40. Date of Electronic Publication: 2018 Dec 10 (Print Publication: 2018).