Brominated Dioxins in Egg, Broiler, and Feed Additives: Significance of Bioassay-Directed Screening for Identification of Emerging Risks in Food

Autor: Caroline Dirks, Arjen Gerssen, Yoran Weide, Thijs Meijer, Guido van der Weg, Milou G. M. van de Schans, Toine F. H. Bovee

Publikováno v: Foods, Vol 13, Iss 6, p 931 (2024)

Food authorities aim to safeguard our food. This requires sensitive analyses to guarantee detection of both banned and regulated substances at low concentrations. At the same time, broad screening methods are needed to identify new emerging risks. Fo

Externí odkaz: https://doaj.org/article/8642486723464164bbf75b6187888830

A Strategy to Replace the Mouse Bioassay for Detecting and Identifying Lipophilic Marine Biotoxins by Combining the Neuro-2a Bioassay and LC-MS/MS Analysis

Autor: Marcia Bodero, Arjen Gerssen, Liza Portier, Mirjam D. Klijnstra, Ron L. A. P. Hoogenboom, Leonardo Guzmán, Peter J. M. Hendriksen, Toine F. H. Bovee

Publikováno v: Marine Drugs, Vol 16, Iss 12, p 501 (2018)

Marine biotoxins in fish and shellfish can cause several symptoms in consumers, such as diarrhea, amnesia, or even death by paralysis. Monitoring programs are in place for testing shellfish on a regular basis. In some countries testing is performed u

Externí odkaz: https://doaj.org/article/6856227e61354d71a775ef9d2d07e8e1

Identification of phosphodiesterase type-5 (PDE-5) inhibitors in herbal supplements using a tiered approach and associated consumer risk

Autor: Felicia Akuamoa, Toine F. H. Bovee, Ruud van Dam, Lilian Maro, Sebastiaan Wesseling, Jacques Vervoort, Ivonne M. C. M. Rietjens, Ron L. A. P. Hoogenboom

Publikováno v: Food Additives and Contaminants-Part A Chemistry, Analysis, Control, Exposure and Risk Assessment 39 (2022) 6
Food Additives and Contaminants-Part A Chemistry, Analysis, Control, Exposure and Risk Assessment, 39(6), 1021-1032

The use of herbal supplements for improved sexual performance is a common practice amongst the youth and some senior citizens in Ghana. These products are considered ‘natural’ and greatly preferred over synthetic alternatives due to the assurance

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::842ba26851e2d72a6000a5aebac9faf9
https://doi.org/10.1080/19440049.2022.2052972

Whole genome mRNA transcriptomics analysis reveals different modes of action of the diarrheic shellfish poisons okadaic acid and dinophysis toxin-1 versus azaspiracid-1 in Caco-2 cells

Autor: Ad A. C. M. Peijnenburg, Laura H.J. de Haan, Ron L.A.P. Hoogenboom, Toine F H Bovee, Liza Portier, Peter J M Hendriksen, Marcia Bodero

Publikováno v: Toxicology in Vitro, 46, 102-112
Toxicology in Vitro 46 (2018)

A study with DNA microarrays was performed to investigate the effects of two diarrhetic and one azaspiracid shellfish poison, okadaic acid (OA), dinophysistoxin-1 (DTX-1) and azaspiracid-1 (AZA-1) respectively, on the whole-genome mRNA expression of

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::de25e5f97f36f8853c23dffc0ca0a531
https://doi.org/10.1016/j.tiv.2017.09.018

A strategy to replace the mouse bioassay for detecting and identifying lipophilic marine biotoxins by combining the neuro-2a bioassay and LC-MS/MS analysis

Autor: Toine F H Bovee, Liza Portier, Peter J M Hendriksen, Ron L.A.P. Hoogenboom, Mirjam D. Klijnstra, Arjen Gerssen, Marcia Bodero, Leonardo Guzmán

Publikováno v: Marine Drugs, 16(12)
Marine Drugs
Volume 16
Issue 12
Marine Drugs, Vol 16, Iss 12, p 501 (2018)
Marine Drugs 16 (2018) 12

Marine biotoxins in fish and shellfish can cause several symptoms in consumers, such as diarrhea, amnesia, or even death by paralysis. Monitoring programs are in place for testing shellfish on a regular basis. In some countries testing is performed u

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::a6de98ea6e676b14b0180e5ccbf9a458
https://research.wur.nl/en/publications/a-strategy-to-replace-the-mouse-bioassay-for-detecting-and-identi