Zobrazeno 1 - 10
of 37
pro vyhledávání: '"Tohru Saeki"'
Publikováno v:
Journal of Power Sources. 238:53-56
An all-solid-state lithium ion battery was constructed with a screen-printing process using Nb doped Li7La3Zr2O12 (LLZONb) as the solid electrolyte and Li3BO3 (LBO) as a solid electrolyte within the cathode layer. LBO is a lithium ion conductor that
Publikováno v:
Bioscience, Biotechnology, and Biochemistry. 71:1865-1872
Although ileal and hepatic Na(+)-dependent bile acid transporters (SLC10A2 and SLC10A1 respectively) share structural similarities, the mutation of conserved amino acids often has distinct effects on them. We have identified two Cys residues in mouse
Autor:
Ryuhei Kanamoto, Tomohiko Suzuka, Yasushi Nakamura, Kozo Ohtsuki, Takeo Komori, Kenji Sato, Noriko Higaki, Hitoshi Suda, Kimikazu Iwami, Tohru Saeki
Publikováno v:
Bioscience, Biotechnology, and Biochemistry. 70:2844-2852
Feeding HMF, an insoluble "high-molecular-weight fraction" from an industrial enzymatic digest of a soy protein isolate, increased the fecal excretion of bile acid concomitant with increased fecal nitrogen. An amino acid analysis revealed that this i
Publikováno v:
The Journal of Biochemistry. 138:151-157
Hydrophobic bile acids induce apoptosis in both colon cancer cells and hepatocytes. The mechanism by which colon cancer cells respond to bile acids is thought to be different from that of hepatocytes. Therefore, we investigated the characteristics of
Autor:
Kei Takahashi, Tohru Saeki, Kazumitsu Ueda, Teruo Amachi, Michinori Matsuo, Yasuhisa Kimura, Noriyuki Kioka
Publikováno v:
Current Drug Metabolism. 5:1-10
P-glycoprotein/MDR1 was the first member of the ATP-binding cassette (ABC) transporter superfamily to be identified in a eukaryote. In eukaryotes, ABC proteins can be classified into three major groups based on function: transporters, regulators, and
Publikováno v:
Molecular pharmacology, 62(5), 1160-1166. American Society for Pharmacology and Experimental Therapeutics
Inhibition of multidrug resistance protein 1 (MRP1) mediated cytostatic drug efflux might be useful in the treatment of drug resistant tumors. Because the glutathione (GSH) conjugate of ethacrynic acid (EA), GS-EA, is a good substrate of MRP1, GS-EA
Publikováno v:
Journal of biological chemistry, 276(49), 46400-46407. American Society for Biochemistry and Molecular Biology Inc.
We have characterized the substrate specificity and mechanism of transport of the human multidrug resistance-associated protein 3 (MRP3). A murine fibroblast-like cell line generated from the kidneys of mice that lack Mdr1a/b and Mrp1 was retrovirall
Autor:
Tohru Saeki, Hiroyuki Iwasaki, Naoyuki Azuma, Hitoshi Suda, Kimikazu Iwami, Natsuko Yamagata, Ryuhei Kanamoto
Publikováno v:
Journal of Nutritional Science and Vitaminology. 46:91-96
In order to obtain information on the preventive effects of various food proteins against colonic cancer, six groups of azoxymethane-initiated mature Fischer rats (n = 10) were fed respective diets different in protein sources such as bovine milk cas
Autor:
Tohru Saeki, Kensuke Kirifuji, Hiroko Furukawa, Keishi Matoba, Ryuhei Kanamoto, Kimikazu Iwami
Publikováno v:
Journal of Biochemistry. 125:846-851
Mouse ileal sodium dependent bile acid transporter (ISBT) was characterized using isolated enterocytes. Only enterocytes from the most distal portion showed Na+-dependent [3H]taurocholate uptake. Northern blot analysis using a probe against mouse ISB
Publikováno v:
BMC Physiology, Vol 13, Iss 1, p 4 (2013)
BMC Physiology
BMC Physiology
Background SLC10A2-mediated reabsorption of bile acids at the distal end of the ileum is the first step in enterohepatic circulation. Because bile acids act not only as detergents but also as signaling molecules in lipid metabolism and energy product