Zobrazeno 1 - 10
of 41
pro vyhledávání: '"Tohru Onogawa"'
Autor:
Tohru Onogawa, Asako Itaya-Hironaka, Akiyo Yamauchi, Maiko Takeda, Hiroshi Okamoto, Hiroyo Ota, Sumiyo Sakuramoto-Tsuchida, Koji Nata, Shoko Murakami-Kawaguchi, Masato Kato, Shin Takasawa
Publikováno v:
Cell and Tissue Research. 355:303-314
A possible cure for diabetes is explored by using non-pancreatic cells such as fetal hepatocytes. The expression of insulin and transcription factors for insulin is investigated in mouse fetal liver. We detected mRNAs for insulin I (Ins1) and insulin
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::7e0204f7cac1d0c7b17c530469b378bb
https://doi.org/10.1007/s00441-013-1741-4
https://doi.org/10.1007/s00441-013-1741-4
Autor:
Tohru Onogawa, Takashi Minowa, Tatsuyuki Takadate, Kiyonaga Fujii, Sayaka Mikami, Shinichi Egawa, Yasuhiko Bando, Toshihide Nishimura, Hideo Ohtsuka, Makoto Kihara, Yu Katayose, Kazuyuki Ishida, Takashi Suzuki, Nobutaka Hanagata, Michiaki Unno, Fuyuhiko Motoi, Shimpei Maeda, Tetsuya Fukuda
Publikováno v:
International Journal of Cancer. 132:1368-1382
Pancreatic cancer is among the most lethal malignancies worldwide. We aimed to identify novel prognostic markers by applying mass spectrometry (MS)-based proteomic analysis to formalin-fixed paraffin-embedded (FFPE) tissues. Resectable, node positive
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::f396ae73eb347d303c6a4c24aacf032e
https://doi.org/10.1002/ijc.27797
https://doi.org/10.1002/ijc.27797
Autor:
Naoaki Sakata, Hiroshi Yoshida, Hiroki Hayashi, Hirotake Komatsu, Yu Katayose, Michiaki Unno, Morihisa Hirota, Fuyuhiko Motoi, Takanori Morikawa, Shinichi Egawa, Toshiki Rikiyama, Tohru Onogawa, Tooru Shimosegawa
Publikováno v:
Clinical Journal of Gastroenterology. 4:249-254
Emphysematous pancreatitis (air in the parenchyma) was previously considered an indication for surgery, but some recent studies have reported good clinical outcomes with non-operative management. As a step toward establishing a better treatment strat
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::027b69668c984a88a5924379a988b313
https://doi.org/10.1007/s12328-011-0229-6
https://doi.org/10.1007/s12328-011-0229-6
Autor:
Kunihiro Masuda, Shinichi Egawa, Takeshi Naitoh, Masanori Akada, Hiroshi Yoshida, Tohru Onogawa, Michiaki Unno, Naoaki Sakata, Yu Katayose, Takanori Morikawa, Kuniharu Yamamoto, Fuyuhiko Motoi, Kei Nakagawa, Toshiki Rikiyama, Hiroki Hayashi, Hideo Ohtsuka, Gumpei Yoshimatsu, Shigeru Ottomo
Publikováno v:
Journal of Gastrointestinal Surgery. 15:525-532
BACKGROUNS/AIMS: There are few studies about the assessment of pancreatic function using computed tomography (CT) volumetry. In this study, we examined the correlation between CT volumetry and endocrine parameters (blood glucose and HbA1c) of the pan
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::2bf8413d15a9b12ddc3fc0369953f3d2
https://doi.org/10.1007/s11605-010-1406-5
https://doi.org/10.1007/s11605-010-1406-5
Autor:
Takehiro Suzuki, Michiaki Abe, Tomokazu Souma, Hirohito Shima, Takafumi Toyohara, Shin Takasawa, Sadayoshi Ito, Tomohiko Shindo, Eisuke Shibata, Yoichi Takeuchi, Yasutoshi Akiyama, Hiromi O. Shiwaku, Tohru Onogawa, Eikan Mishima, Michiaki Unno, Tetsuya Terasaki, Takaaki Abe, Naoya Noguchi, Guodong Zheng, Akiko Ishii, Masayuki Tanemoto, Rie Nakagomi-Hagihara
Publikováno v:
Drug Metabolism and Pharmacokinetics. 25:274-282
The 3-hydroxy-3-methylglutaryl coenzyme A reductase inhibitor pravastatin has been reported to have a beneficial effect on reducing the new onset of diabetes as well as lowering plasma lipids. Because pravastatin is a water-soluble organic anion, it
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::60909877942178fee45cd57f451297fa
https://doi.org/10.2133/dmpk.25.274
https://doi.org/10.2133/dmpk.25.274
Autor:
Tohru Onogawa, Noriaki Ohuchi, Yu Katayose, Takanori Ishida, Takaaki Abe, Hironobu Sasano, Toshiki Rikiyama, Takashi Suzuki, Mitsuhisa Muto, Michiaki Unno
Publikováno v:
Cancer Science. 98:1570-1576
Human liver-specific organic anion transporter-2 (LST-2/OATP8/SLCO1B3) has been demonstrated to be expressed in various gastrointestinal carcinomas and also to play pivotal roles in the uptake of a wide variety of both endogenous and exogenous anioni
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::fda9e209a3bfca3921ad26af8da5cb25
https://doi.org/10.1111/j.1349-7006.2007.00570.x
https://doi.org/10.1111/j.1349-7006.2007.00570.x
Autor:
Tohru Onogawa, Takuya Moriya, Naoko Sato, Hitoshi Niikura, Tadao Takano, Kyoko Ota, Michiaki Unno, Nobuo Yaegashi, Kiyoshi Ito, Jun Ichi Akahira, Takaaki Abe
Publikováno v:
International Journal of Gynecological Pathology. 26:334-340
The SLC22A16 is one of the newly isolated organic cation transporters, which is responsible for uptake and transport of adriamycin into cells. Adriamycin is considered to be an active agent for ovarian cancer. Recently, the benefit of adding adriamyc
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::7dadb2484e4c4704b2281bb71c837e33
https://doi.org/10.1097/01.pgp.0000236951.33914.1b
https://doi.org/10.1097/01.pgp.0000236951.33914.1b
Autor:
Tohru Onogawa, Noriko Kondo, Takaaki Abe, Yu Katayose, Michiaki Unno, Tsuyoshi Mikkaichi, Takeaki Sato, Hideo Ohtsuka, Hiroshi Oshio, Hiroya Mizutamari, Masaya Oikawa, Toshiki Rikiyama
Publikováno v:
Journal of Gastroenterology. 41:369-377
We isolated the human liver-specific organic anion transporter gene, LST-2 (OATP8/SLCO1B3), which is exclusively expressed in the basolateral membrane of the hepatocytes. In this study, we analyzed the transcriptional regulation of the LST-2 gene in
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::775209479af16fb03e0ad12f7881b2fb
https://doi.org/10.1007/s00535-006-1784-3
https://doi.org/10.1007/s00535-006-1784-3
Publikováno v:
American Journal of Physiology-Renal Physiology. 287:F1148-F1153
Kir5.1, a nonfunctional inwardly rectifying K+ channel by itself, can form functional channels by assembling with other proteins. We previously showed that Kir5.1 assembled with Kir4.1 and functioned as an acid-base regulator in the kidney. In this s
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::97eb1c77a462dd4e2aa2456857ef0404
https://doi.org/10.1152/ajprenal.00203.2004
https://doi.org/10.1152/ajprenal.00203.2004
Molecular cloning, expression and chromosomal localization of a novel human REG family gene, REG III
Autor:
Akiyo Yamauchi, Shin Takasawa, Yi Liu, Tohru Onogawa, Nausheen J. Shervani, Liqing Xu, Naoya Noguchi, Takako Akiyama, Takayuki Ikeda, Hiroshi Okamoto, Koji Nata, Shoko Kawaguchi, Iwao Takahashi
Publikováno v:
Gene. 340:161-170
Regenerating gene (Reg), first isolated from a regenerating islet cDNA library [J. Biol. Chem. 263 (1988) 2111], encodes a secretory protein with a growth stimulating effect on pancreatic β cells that ameliorates the diabetes of 90% depancreatized r
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::1ae39d874f4b5dd2e8371b433d6031be
https://doi.org/10.1016/j.gene.2004.06.010
https://doi.org/10.1016/j.gene.2004.06.010