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Akademický článek

Unified synthesis of NOPQ and STUV rings of brevisulcenal-F.

Autor: Sho Kawamurara, Kanako Toriyama, Keitaro Umeno, Yoko Yasuno, Masayuki Satake, Tohru Oishi

Publikováno v: Chemistry Letters; Sep2024, Vol. 53 Issue 9, p1-6, 6p

Amphotericin B assembles into seven-molecule ion channels: An NMR and molecular dynamics study

Autor: Michio Murata, Hiroshi Tsuchikawa, Shinya Hanashima, Tohru Oishi, Sangjae Seo, Tomoya Yamamoto, Kosuke Funahashi, Taiga Suzuki, Shigeru Matsuoka, Nobuaki Matsumori, Mayank Kumar Dixit, Yuichi Umegawa, Yasuo Nakagawa, Wataru Shinoda

Publikováno v: Science Advances. 8

Amphotericin B, an antifungal drug with a long history of use, forms fungicidal ion-permeable channels across cell membranes. Using solid-state nuclear magnetic resonance spectroscopy and molecular dynamics simulations, we experimentally elucidated t

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::4c02c60be5188ed6efe6bc422691d881
https://doi.org/10.1126/sciadv.abo2658

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Structure Determination, Chemical Synthesis, and Evaluation of Biological Activity of Super Carbon Chain Natural Products

Autor: Tohru Oishi

Publikováno v: Bulletin of the Chemical Society of Japan. 93:1350-1360

Marine microorganisms are known to produce natural products, so called super carbon chain compounds whose molecular weights (MWs) exceed one thousand, such as amphidinol 3 (AM3) and maitotoxin (MTX...

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_________::5ff51f0aed33570cf3f90bd3cef60ef2
https://doi.org/10.1246/bcsj.20200151

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Simple Apparatus for Adding Small Amounts of Powder Materials under an Inert Atmosphere

Autor: Kohei Torikai, Yohei Joh, Tohru Oishi, Shamansur S. Sagdullaev, Khamid U. Khodjaniyazov, Milandip Karak

Publikováno v: Synlett. 30:2058-2061

Addition of reactants under an inert atmosphere is a fundamental but extremely important technique in synthetic chemistry. Although this is achievable in many cases by using a glove box or a Schlenk-and-syringe technique, the direct addition of powde

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_________::17a1e57136a6827b0be7563759179ab1
https://doi.org/10.1055/s-0039-1690689

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Unified Synthesis of the DEF and GHI Ring Systems of Maitotoxin

Autor: Takaya Yasudomi, Makoto Ebine, Kohei Torikai, Hiroyuki Yakushiji, Tohru Oishi

Publikováno v: Chemistry Letters. 48:1156-1159

Unified synthesis of 6/6/6-tricyclic ethers corresponding to the DEF and GHI ring systems of maitotoxin was achieved from a common intermediate prepared from a furan derivative and a terminal olefi...

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_________::d8e5b99e3b5f1ca93334c452fb886040
https://doi.org/10.1246/cl.190479

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1,2-trans Glycosylation via Neighboring Group Participation of 2-O-Alkoxymethyl Groups: Application to One-Pot Oligosaccharide Synthesis

Autor: Milandip Karak, Kohei Torikai, Masahiko Suenaga, Yohei Joh, Tohru Oishi

Publikováno v: Organic Letters. 21:1221-1225

The use of 2- O-alkoxymethyl groups as effective stereodirecting substituents for the construction of 1,2- trans glycosidic linkages is reported. The observed stereoselectivity arises from the intramolecular formation of a five-membered cyclic archit

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::3237856f4437bc333eac974d43ad5a40
https://doi.org/10.1021/acs.orglett.9b00220

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