Zobrazeno 1 - 7
of 7
pro vyhledávání: '"Tohru Ohuchi"'
Publikováno v:
Proceedings of the National Academy of Sciences. 89:7900-7904
The retinoblastoma gene product (the RB protein) is phosphorylated in a cell cycle-dependent manner and this modification is believed to be important for cells to progress through the cell cycle. We found that purified cdk2 (cyclin-dependent kinase/c
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::bf51b61d8334c2fa01ee4a78b4437dfb
https://doi.org/10.1073/pnas.89.17.7900
https://doi.org/10.1073/pnas.89.17.7900
Autor:
Shonen Yoshida, Tohru Ohuchi, Motoshi Suzuki, Takeshi Sakurai, Katsuyuki Tamai, Kyohide Kojima, Tetsu Akiyama, Ericka Savoysky
Publikováno v:
Biochemical and Biophysical Research Communications. 187:697-702
Rb protein was purified from recombinant baculovirus-infected Sf9 cells to apparent homogeneity by a simple solubilization and by immunoaffinity column chromatography. It was mainly obtained as p110Rb, the underphosphorylated form of the Rb protein f
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::43c7c15ecfb08481147a09359917f1c1
https://doi.org/10.1016/0006-291x(92)91251-k
https://doi.org/10.1016/0006-291x(92)91251-k
Publikováno v:
Molecular and Cellular Biology. 11:4088-4096
A new transforming gene has been molecularly cloned from hamster SHOK cells transformed with DNA extracted from a human thyroid carcinoma cell line and named the cot (cancer Osaka thyroid) oncogene. cDNA sequencing disclosed that this oncogene codes
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::387881903ad871303f07e9c29c31b6df
https://doi.org/10.1128/mcb.11.8.4088-4096.1991
https://doi.org/10.1128/mcb.11.8.4088-4096.1991
Autor:
Tohru Ohuchi, Beatrice S. Knudsen, Christoph Schumacher, Hidesaburo Hanafusa, Pier Paolo Di Fiore, Robert H. Glassman
Publikováno v:
The Journal of biological chemistry. 270(25)
The Crk protein belongs to the family of proteins consisting of mainly Src homology 2 and 3 (SH2 and SH3) domains. These proteins are thought to transduce signals from tyrosine kinases to downstream effectors. In order to understand the specificity a
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::1af6245bc3f94f583c64b00777b99ce5
https://pubmed.ncbi.nlm.nih.gov/7797522
https://pubmed.ncbi.nlm.nih.gov/7797522
Publikováno v:
The Tohoku journal of experimental medicine. 168(2)
AKIYAMA, T., OHUCHI, T., SUMIDA, S., XU, S. and TOYOSHIMA, K. Phosphorylation of the Antioncogene Products and Control of the Cell Cycle. Tohoku J. Exp. Med., 1992, 168 (2), 153-157-To investigate the function of the RB protein, we have studied cellu
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::8f309eddc3b314b5b1a74f3db466d7b7
https://pubmed.ncbi.nlm.nih.gov/1306298
https://pubmed.ncbi.nlm.nih.gov/1306298
Autor:
Tohru Ohuchi, Takeo Kakunaga, Hitoshi Sasai, Jun Miyoshi, Takesada Mori, Fumio Suzuki, Shin-ichiro Takai, Takatsugu Higashi
Publikováno v:
Proceedings of the National Academy of Sciences of the United States of America. 87(7)
We established a subclone, SHOK, from the GHE-L cell line, an immortal line derived from a primary culture of Syrian hamster embryo cells, as a recipient cell line useful for the detection of oncogenes by transfection. SHOK cells were almost as susce
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::bf16b4d1e092f960d72df985e463e1b1
https://pubmed.ncbi.nlm.nih.gov/2181436
https://pubmed.ncbi.nlm.nih.gov/2181436
Autor:
Tetsu Akiyama, Katsuyuki Tamai, Tohru Ohuchi, Takeshi Sakurai, Motoshi Suzuki, Ericka Savoysky, Shonen Yoshida, Kiyohide Kojima
Publikováno v:
Biochemical and Biophysical Research Communications. 188:956
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::b6745d004b4c209484bafe531e8510b5
https://doi.org/10.1016/0006-291x(92)91148-j
https://doi.org/10.1016/0006-291x(92)91148-j