Zobrazeno 1 - 10
of 15
pro vyhledávání: '"Tohru Nagasaki"'
Autor:
Tohru Nagasaki, Akira Yamauchi, Kazuhiko Maekawa, Keiko Kawamoto, Ikuko Nishino, Koji Enomoto, Shino Kikuoka, Takahiro Fukunaga, Junji Onoda, Yoshito Numata, Yuko Kinoshita, Tetsuya Yoshida, Hiroshi Takemoto, K. Sakai, Kiyoshi Nagata
Publikováno v:
Analytical Biochemistry. 351:229-240
Spermidine synthase (SPDS) catalyzes transfer of the propylamine group from decarboxylated S-adenosylmethionine (dcSAM) to putrescine to yield methylthioadenosine (MTA) and spermidine. SPDS plays a regulatory role in cell proliferation and differenti
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::7da109c465a439cbdad88500392bbbc9
https://doi.org/10.1016/j.ab.2006.01.012
https://doi.org/10.1016/j.ab.2006.01.012
Autor:
Yozo Hori, Toshiyuki Sakaeda, Kohji Hanasaki, Tohru Nagasaki, Hitosi Nakazato, Junji Kishino, Nobuo Takasu, Gaku Sakaguchi, Naohiro Itoh, Yoshihiko Katsuyama, Tatsurou Yagami, Noboru Okamura, Keiichi Ueda, Akinori Arimura, Masafumi Fujimoto, Kenji Asakura
Publikováno v:
Experimental Cell Research. 291:212-227
15-Deoxy-Delta12,14-prostaglandin J2 (15d-Delta12,14-PGJ2) is an endogenous ligand for a nuclear peroxysome proliferator activated receptor-gamma (PPAR). We found novel binding sites of 15d-Delta12,14-PGJ2 in the neuronal plasma membranes of the cere
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::09a209e410e18c9938ba0554dc15b454
https://doi.org/10.1016/s0014-4827(03)00369-0
https://doi.org/10.1016/s0014-4827(03)00369-0
Autor:
Masahiro Koike, Shozo Takechi, Yoshihiko Katsuyama, Masaharu Segawa, K. Sakai, Tohru Nagasaki, Kenji Kawada, Nobuhiro Haga
Publikováno v:
Journal of Labelled Compounds and Radiopharmaceuticals. 44:993-1004
Summary A simple, mild and versatile new tritium ( 3 H) labelling method on a micro scale using sodium borotritide (NaB 3 H4) and a transition–metal complex catalyst is described. 3 H-labelled compounds were prepared effectively by 3 H hydrogenolys
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::dab2a1c572cc1bd95cdebf4e8bbe5f8b
https://doi.org/10.1002/jlcr.521
https://doi.org/10.1002/jlcr.521
Publikováno v:
Journal of Labelled Compounds and Radiopharmaceuticals. 31:23-38
(+)-S-145 and S-1452, thromboxane A2 receptor antagonists, were labelled with 3H and 14C for studies on the metabolic fate and characterization of receptor binding. 3H and 14C were incorporated into the benzene ring in the phenysulfonylamide side cha
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::3c6a1eaeb7cb306365061d5a4f2a4d3d
https://doi.org/10.1002/jlcr.2580310105
https://doi.org/10.1002/jlcr.2580310105
Publikováno v:
Nutrition Research. 10:547-554
Rats that had been adapted to meal-feeding were given a definite amount of soy protein- or casein-based diet containing [ 14 C]taurocholate, and examined for nostprandial changes in intraluminal level as well as mucosal accumulation of the radioactiv
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::6c9337b830c1280ca71deed27a2d936e
https://doi.org/10.1016/s0271-5317(05)80064-8
https://doi.org/10.1016/s0271-5317(05)80064-8
Publikováno v:
British journal of pharmacology. 103(4)
1. The mechanism for the stereospecific recognition of the antagonist S-145 by the thromboxane A2 (TXA2)/prostaglandin H2 (PGH2) receptor was examined by ligand-binding techniques in rat vascular smooth muscle cells (VSMCs) and in human platelet memb
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::495d27868e27968fd0d6b775e2ef8869
https://pubmed.ncbi.nlm.nih.gov/1833018
https://pubmed.ncbi.nlm.nih.gov/1833018
Autor:
Machiko Nakanishi, Yoshihiko Katsuyama, Kenji Mizojiri, Shinya Futaguchi, Ryo Norikura, Takeo Yoshimori, Tohru Nagasaki
Publikováno v:
Antimicrob Agents Chemother
[pivaloyl-14C]S-1108, which is 14C labeled at the pivalic acid moiety of the pivaloyloxymethyl side chain of S-1108, was administered orally to rats and dogs, and the disposition of pivalic acid cleft from S-1108 was examined. Besides pivaloylcarniti
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::ca488fc1f0aae8041e8f180b7a6f6455
https://doi.org/10.1128/aac.39.10.2373a
https://doi.org/10.1128/aac.39.10.2373a
Publikováno v:
Journal of Labelled Compounds and Radiopharmaceuticals. 19:981-990
Latamoxef (I) was labelled with 14C for metabolic and pharmacological studies. The carbon-14 label was introduced into the C-1 position and the C-2 position of the amido side chain to prepare (II) and (III) in overall yields of 10.6 and 13.5% based o
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::b3ba801ab1b265dbab5cac45cae6bbf7
https://doi.org/10.1002/jlcr.2580190812
https://doi.org/10.1002/jlcr.2580190812
Publikováno v:
Biochemical Pharmacology. 38:2007-2017
The specific binding sites for S-145, a novel thromboxane A2/prostaglandin H2 (TXA2/PGH2) receptor antagonist with weak partial agonistic activity, were studied in human platelet membranes. [3H]S-145 displayed high affinity and specificity, as well a
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::786ef2eb880e81655aacdf7cf1f3a0ef
https://doi.org/10.1016/0006-2952(89)90501-7
https://doi.org/10.1016/0006-2952(89)90501-7
Autor:
Hitoshi Minato, Tohru Nagasaki
Publikováno v:
J. Chem. Soc. C. :1866-1872
The structure of a furanosesquiterpene, atractylon, isolated from Atractylis ovata Thunb and Atractylodes japonica Koizumi, was established by Yosioka and his co-workers. As starting material for the synthesis of atractylon, 2,3,4,6,7,8-hexahydro-2-o
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::813c1e5c29b366b188334c5b789d008b
https://doi.org/10.1039/j39660001866
https://doi.org/10.1039/j39660001866