Zobrazeno 1 - 10
of 27
pro vyhledávání: '"Tohru Miura"'
Autor:
Takayuki Matsuda, Ayumu Okuda, Yuki Yamaguchi, Ayako Tosaka, Yuichiro Watanabe, Kimiyuki Shibuya, Minoru Koura, Koichi Yamazaki, Tohru Miura, Sayaka Kurobuchi, Hidefumi Ozawa
Publikováno v:
Bioorganic & Medicinal Chemistry Letters. 25:1274-1278
In an attempt to molecularly design liver X receptor (LXR) β-selective agonists, we discovered that the combination of the 2-oxochromene moiety (head) and the imidazoline-2,4-dione moiety (tail) plays an important role in the expression potency and
Autor:
Kohji Kusano, Takehiko Usui, Masa-Toshi Yamamoto, Hiroaki I. Ogawa, Tohru Miura, Yoshimasa Yamana
Publikováno v:
Genetics. 191:65-78
Synthesis-dependent strand-annealing (SDSA)-mediated homologous recombination replaces the sequence around a DNA double-strand break (DSB) with a copy of a homologous DNA template, while maintaining the original configuration of the flanking regions.
Publikováno v:
Molecular and Cellular Endocrinology. 327:25-39
Here we report the identification and characterization of ghrelin (GRLN) receptors in goldfish Carassius auratus. We identified four distinct mRNAs generated from four different genes. Those were roughly divided into two types, based on the number of
Autor:
Hironori Ando, Sei-Ichi Shimakura, Kenji Kojima, Alciyoshi Takahashi, Minoru Uchiyama, Seiji Shioda, Kouhei Matsuda, Tohru Miura
Publikováno v:
Comparative Biochemistry and Physiology Part A: Molecular & Integrative Physiology. 153:3-7
Intracerebroventricular (ICV) administration of melanin-concentrating hormone (MCH) inhibits food intake in goldfish, unlike the orexigenic action in rodents, via the melanocortin system with suppression of neuropeptide Y (NPY) mRNA expression. We th
Autor:
Minoru Uchiyama, Sei-Ichi Shimakura, Kouta Nakamura, Tohru Miura, Seiji Shioda, Kouhei Matsuda, Hironori Ando, Haruaki Kageyama
Publikováno v:
Hormones and Behavior. 54:83-89
Gonadotropin-releasing hormone (GnRH) is an evolutionarily conserved neuropeptide with 10 amino acid residues, which possesses some structural variants. A molecular form known as chicken GnRH II ([His(5) Trp(7) Tyr(8)] GnRH, cGnRH II) is widely distr
Autor:
Seiji Shioda, Kouhei Matsuda, Keisuke Maruyama, Sei-Ichi Shimakura, Kenji Kangawa, Tohru Miura, Hiroyuki Kaiya, Minoru Uchiyama
Publikováno v:
Peptides. 28:1207-1213
Intracerebroventricular (ICV) administration of ghrelin, orexin and neuropeptide Y (NPY) stimulates food intake in goldfish. Orexin and NPY interact with each other in the regulation of feeding, while ghrelin-induced feeding has also shown to be medi
Publikováno v:
Journal of Wood Science. 45:492-497
The physical properties of sawdust including porosity, water retention, and water drainage were analyzed to prove its suitability for use as an artificial soil in the automatic decomposer-extinguisher (GADE) machine. The physical and chemical propert
Publikováno v:
Proceedings of the National Academy of Sciences of the United States of America. 110(40)
DNA damage alone or DNA replication fork arrest at damaged sites may induce DNA double-strand breaks and initiate homologous recombination. This event can result in a crossover with a homologous chromosome, causing loss of heterozygosity along the ch
Publikováno v:
Kanzo. 33:967-973
大網の異所性肝組織より発生した肝細胞癌の1切除例を報告する.症例は68歳の男性で可動性を有する右季肋部腫瘤を触知し,腹部超音波検査,CTで肝右葉下縁に接する腫瘍を指摘され,精査目
Autor:
Seiji Shioda, Kouhei Matsuda, Tohru Miura, Minoru Uchiyama, Hiroyuki Kaiya, Kenji Kangawa, Mikiya Miyazato, Keisuke Maruyama
Publikováno v:
Peptides. 30(4)
In goldfish, intraperitoneal (IP) or intracerebroventricular (ICV) administration of synthetic ghrelin consisting of 12- or 19-amino-acid residues, deduced from its precursor cDNA, with an octanoic acid modification at the third N-terminal serine res