Zobrazeno 1 - 10 of 23 pro vyhledávání: '"Tohru Ito"'
1
Akademický článek
Novel PKD2 Missense Mutation p.Ile424Ser in an Individual with Multiple Hepatic Cysts: A Case Report
Autor: Seiko Miura, Yo Niida, Chieko Hashizume, Ai Fujii, Yuta Takagaki, Kahoru Kusama, Sumiyo Akazawa, Tetsuya Minami, Tsuyoshi Mukai, Kengo Furuichi, Mutsumi Tsuchishima, Nobuhiko Ueda, Hiroyuki Takamura, Daisuke Koya, Tohru Ito
Publikováno v: Medicines, Vol 9, Iss 4, p 25 (2022)
We report a novel missense mutation, p.Ile424Ser, in the PKD2 gene of an autosomal dominant polycystic kidney disease (ADPKD) patient with multiple liver cysts. A 57-year-old woman presented to our university hospital with abdominal fullness, decreas
Externí odkaz: https://doaj.org/article/53bc3d2979f943a3aed29a2c47fc9887
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3
Akademický článek
Development of a high throughput system to screen compounds that revert the activated hepatic stellate cells to a quiescent-like state
Autor: Yasuhiro Nakano, Eiko Saijou, Tohru Itoh, Minoru Tanaka, Atsushi Miyajima, Taketomo Kido
Publikováno v: Scientific Reports, Vol 14, Iss 1, Pp 1-9 (2024)
Abstract Chronic liver injury induces fibrosis that often proceeds to cirrhosis and hepatocellular carcinoma, indicating that prevention and/or resolution of fibrosis is a promising therapeutic target. Hepatic stellate cells (HSCs) are the major driv
Externí odkaz: https://doaj.org/article/5dfc9d6cb6644a27a78fe1b6b36ad4c8
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5
Bleeding Risk Factors after Endoscopic Submucosal Dissection in Early Gastric Cancer and the Necessity of 'Second-Look' Endoscopic Examination on the following Day
Autor: Rika Kobayashi, Ken Kawaura, Tohru Ito, Sadafumi Azukisawa, Hiroaki Kunou, Junji Kamai, Kazu Hamada, Tsuyoshi Mukai, Hidekazu Kitakata, Yasuhito Ishigaki
Publikováno v: Journal of Clinical Medicine; Volume 11; Issue 4; Pages: 914
Background and Aim: Hemorrhage is often encountered after endoscopic submucosal dissection (ESD). In addition to active bleeding after resection, exposed blood vessels and blood clots without active bleeding on the post-dissection ulcer floor have be
Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::4aff3f8bf47ffdf5c5567a1f30383601
https://doi.org/10.3390/jcm11040914
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6
Akademický článek
Analysis of distribution, collection, and confirmation of capacity dependency of small extracellular vesicles toward a therapy for liver cirrhosis
Autor: Nobutaka Takeda, Atsunori Tsuchiya, Masaki Mito, Kazuki Natsui, Yui Natusi, Yohei Koseki, Kei Tomiyoshi, Fusako Yamazaki, Yuki Yoshida, Hiroyuki Abe, Masayuki Sano, Taketomo Kido, Yusuke Yoshioka, Junichi Kikuta, Tohru Itoh, Ken Nishimura, Masaru Ishii, Takahiro Ochiya, Atsushi Miyajima, Shuji Terai
Publikováno v: Inflammation and Regeneration, Vol 43, Iss 1, Pp 1-14 (2023)
Abstract Background The progression of liver fibrosis leads to portal hypertension and liver dysfunction. However, no antifibrotic agents have been approved for cirrhosis to date, making them an unmet medical need. Small extracellular vesicles (sEVs)
Externí odkaz: https://doaj.org/article/33ffc1abeeee43bea1671cd58272c823
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7
Akademický článek
Two distinct Notch signals, Delta-like 4/Notch1 and Jagged-1/Notch2, antagonistically regulate chemical hepatocarcinogenesis in mice
Autor: Yasuhiro Nakano, Sachie Nakao, Minako Sueoka, Daigo Kasahara, Yuri Tanno, Hideaki Sumiyoshi, Tohru Itoh, Atsushi Miyajima, Katsuto Hozumi, Yutaka Inagaki
Publikováno v: Communications Biology, Vol 5, Iss 1, Pp 1-10 (2022)
Dll4/Notch1 signal promotes the progression of HCC, while Jag1/Notch2 signal antagonistically suppresses it in murine chemical hepatocarcinogenesis. Nakano et al. report that two distinct Notch signals regulate the progression of hepatocellular carci
Externí odkaz: https://doaj.org/article/b8d8d5deaba64e4cbc50de2a16ed8551
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8
Characterization of the human FcγRIIB gene promoter: human zinc-finger proteins (ZNF140 and ZNF91) that bind to different regions function as transcription repressors
Autor: Tadahiro Nishimura, Tadayoshi Taniyama, Tadashi Narita, Kazuyuki Yoshizaki, Norihiro Nishimoto, Tohru Ito, Henrik Vissing, Eric J. Bellfroid, Joseph Martial, Emi Miyazaki
Publikováno v: International Immunology. 13:1075-1084
Expression of the human low-affinity Fc receptors for IgG (human Fc gamma RII) is differentially regulated. We report here the characterization of the promoter structure of the human Fc gamma RIIB gene and the isolation of the promoter region-binding
Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::c0eba9f3259c4c032f1be627ac7aebd4
https://doi.org/10.1093/intimm/13.8.1075
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9
Akademický článek
nPTD classification: an updated classification of gastric cancer location for function preserving gastrectomy based on physiological lymphatic flow
Autor: Shinichi Kinami, Naohiko Nakamura, Tomoharu Miyashita, Hidekazu Kitakata, Sachio Fushida, Takashi Fujimura, Tohru Itoh, Hiroyuki Takamura
Publikováno v: BMC Cancer, Vol 21, Iss 1, Pp 1-10 (2021)
Abstract Background The correlation between tumor location and lymphatic flow distribution in gastric cancer has been previously reported, and PTD (Proximal – Transitional – Distal) classification was proposed. Our group updated and developed the
Externí odkaz: https://doaj.org/article/2d2e637ae4f24f4896f2e8dcc76453f8
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10
Akademický článek
The truth lies somewhere in the middle: the cells responsible for liver tissue maintenance finally identified
Autor: Tohru Itoh
Publikováno v: Cell Regeneration, Vol 10, Iss 1, Pp 1-4 (2021)
Externí odkaz: https://doaj.org/article/6ee15719a3ce480f85d165ea23220106
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