Zobrazeno 1 - 10
of 232
pro vyhledávání: '"Tohru Hino"'
Publikováno v:
Journal of the Chemical Society, Perkin Transactions 1. :3487-3494
Eudistomins L, K, C, E (30) and F (33) were synthesized from the corresponding N-hydroxytryptamine 21 and the D-cysteinal 23. A bromine of eudistomin L was biomimetically introduced onto the pyrroloindolic intermediate 8. Other eudistomins were prepa
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::4e1d1f825386522f8b7d61da7c5a339b
https://doi.org/10.1039/b004424p
https://doi.org/10.1039/b004424p
Autor:
Masako Nakagawa, Jin-Jun Liu, Makoto Ariga, Tohru Hino, Yasunori Asada, N. Harada, Akihiko Tsuruoka
Publikováno v:
Journal of the Chemical Society, Perkin Transactions 1. :3477-3486
Formation of the oxathiazepine ring in eudistomins 1 was investigated. Thiazolidinyl-β-carboline 5 was successfully transformed into thiaindoloquinolizidine 7, but attempted oxidative transformation of 7 to 1 was not successful. The oxidative cycliz
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::c3432c052a22fd71173de5887b75e908
https://doi.org/10.1039/b004570p
https://doi.org/10.1039/b004570p
Autor:
Shigemasa Tani, Toshio Kushiro, Kagari Matsudaira, Junji Kusama, Fumio Saito, Satoru Kikuchi, Hiroshi Takahashi, Tomohiro Nakayama, Ken Nagao, Katsuo Kanmatsuse, Takako Imazeki, Tohru Hino, Yuichi Sato, Shinobu Imai, Ikuyoshi Watanabe
Publikováno v:
Heart and Vessels. 20:123-125
A transient left ventricular apical ballooning (so-called "ampulla" or "Takotsubo-shaped" cardiomyopathy) with type I CD36 deficiency is described in a 71-year-old woman. The patient was referred because of chest pain and worsening of dyspnea. Electr
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::14b20f2ce36dddfc7c1f89dcd03601ea
https://doi.org/10.1007/s00380-004-0787-3
https://doi.org/10.1007/s00380-004-0787-3
Autor:
Takamasa Iimori, Tohru Hino, Akihiro Hashimoto, Mieko Nagasawa, Masako Nakagawa, Yasuhiro Torisawa, Miwa Okouchi
Publikováno v:
Bioorganic & Medicinal Chemistry Letters. 6:2565-2570
Manzamine C congeners with modified azacyclic rings were synthesized using a DPPA-promoted conjunction of the β-carboline-1-acetate salt with various amines as a key reaction. A preliminaly biological evaluation revealed that these analogues retaine
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::c3cec60d879f917edc1cf30e5a603565
https://doi.org/10.1016/0960-894x(96)00460-x
https://doi.org/10.1016/0960-894x(96)00460-x
Autor:
Tohru Hino, Yumiko Motohashi, Kiyoshi Tanabe, Masako Nakagawa, Toshihiro Hosaka, Naoko Suzuki, Yasuhiro Torisawa
Publikováno v:
Tetrahedron. 52:10597-10608
Synthesis of the tetracyclic core ( 19 ) of manzamine A ( 1 ) was achieved via Diels-Alder reaction of the dihydropyridinones ( 5 , 6 ). Conversion of the two D-A products ( 7 , 8 ) to the key tricyclic ketone ( 10 ) was conducted through a conventio
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::ca5921a3f1e3f2a18e04d73d8540bc7e
https://doi.org/10.1016/0040-4020(96)00607-2
https://doi.org/10.1016/0040-4020(96)00607-2
Autor:
Tohru Hino, Masako Nakagawa
Publikováno v:
Journal of Heterocyclic Chemistry. 31:625-630
Recently many bioactive indole alkaloids have been isolated from marine organisms. Many of them have novel ring systems which are not found in the indole alkaloids isolated from higher plants and molds on the land. We have chosen β-carboline alkaloi
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::13c1611c0e72d1bf678ae5c0499cff27
https://doi.org/10.1002/jhet.5570310304
https://doi.org/10.1002/jhet.5570310304
Publikováno v:
Chemical and Pharmaceutical Bulletin. 42:9-18
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::15fe21a15629c341399983ef04f24202
https://doi.org/10.1248/cpb.42.9
https://doi.org/10.1248/cpb.42.9
Autor:
Kimio Okamura, Tohru Hino, Tadamasa Date, Kiyoshi Tanabe, Masako Nakagawa, Toshihiro Hosaka, Yasuhiro Torisawa
Publikováno v:
Tetrahedron Letters. 34:4543-4546
A construction of the central tetracyclic core ( 19 ) of manzamine A ( 1 ) was successfully achieved by a highly efficient Diels-Alder reaction of the suitably protected dihydropyridinones ( 5 ) and Danishefsky's diene as a key strategy. Expedient co
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::21b5947ecbb6332732cdcd69cfbfde3d
https://doi.org/10.1016/0040-4039(93)88081-s
https://doi.org/10.1016/0040-4039(93)88081-s
Publikováno v:
Tetrahedron. 49:1739-1748
Asymmetric reduction of imines were studied using dialkoxyborane 1 . Dihydro-β-carboline 5a showed moderate (42%ee) and N -phenylketimine 10 higher enantioselectivity (73%ee). Asymmetric reduction of ketones with oxazaborolidine 33 showed high ennat
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::b17c684d0364904084dfb84d5adcb244
https://doi.org/10.1016/s0040-4020(01)80531-7
https://doi.org/10.1016/s0040-4020(01)80531-7
Publikováno v:
Chemical and Pharmaceutical Bulletin. 41:287-291
A new general procedure for the alkylation of the C=N double bond of 3, 4-dihydro-β-carboline has been developed with amphiphilic reaction systems such as BF3·OEt2/RLi, RMgX, R2CuLi or trimethylsilyl trifluoromethane-sulfonate/RLi, RMgX to give the
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::41231fd841f4e46277e886f5bddc93f0
https://doi.org/10.1248/cpb.41.287
https://doi.org/10.1248/cpb.41.287