Zobrazeno 1 - 10
of 180
pro vyhledávání: '"Tohru Dairi"'
Autor:
Yu Nakashima, Atsushi Kawakami, Yasushi Ogasawara, Masatoshi Maeki, Manabu Tokeshi, Tohru Dairi, Hiroyuki Morita
Publikováno v:
Nature Communications, Vol 14, Iss 1, Pp 1-12 (2023)
Abstract The lasso peptide MS-271 is a ribosomally synthesized and post-translationally modified peptide (RiPP) consisting of 21 amino acids with D-tryptophan at the C-terminus, and is derived from the precursor peptide MslA. MslH, encoded in the MS-
Externí odkaz:
https://doaj.org/article/30d4da2d31ea4565ae031fba06ccc808
Autor:
Yung-Lin Wang, Chin-Yuan Chang, Ning-Shian Hsu, I-Wen Lo, Kuan-Hung Lin, Chun-Liang Chen, Chi-Fon Chang, Zhe-Chong Wang, Yasushi Ogasawara, Tohru Dairi, Chitose Maruyama, Yoshimitsu Hamano, Tsung-Lin Li
Publikováno v:
Nature Communications, Vol 14, Iss 1, Pp 1-14 (2023)
Abstract Oxidized cysteine residues are highly reactive and can form functional covalent conjugates, of which the allosteric redox switch formed by the lysine-cysteine NOS bridge is an example. Here, we report a noncanonical FAD-dependent enzyme Orf1
Externí odkaz:
https://doaj.org/article/d86e54a33b7e49ebbea9cb2bf226eb74
Autor:
Yamato Takeuchi, Kazunori Ushimaru, Kohei Kaneda, Chitose Maruyama, Takashi Ito, Kazuya Yamanaka, Yasushi Ogasawara, Hajime Katano, Yasuo Kato, Tohru Dairi, Yoshimitsu Hamano
Publikováno v:
Communications Biology, Vol 5, Iss 1, Pp 1-14 (2022)
Bacteria-derived polycationic homopoly(amino acid)s are reported for the first time to directly penetrate cell membrane and deliver proteins of interest into cells, representing a new type of cell penetrating peptides for intracellular delivery.
Externí odkaz:
https://doaj.org/article/965b0e9e00634fa1934485e4592757fe
Autor:
Yasushi Ogasawara, Tohru Dairi
Publikováno v:
Frontiers in Microbiology, Vol 9 (2018)
D-Amino acid residues have been identified in peptides from a variety of eukaryotes and prokaryotes. In microorganisms, UDP-N-acetylmuramic acid pentapeptide (UDP-MurNAc-L-Ala-D-Glu-meso-diaminopimelate-D-Ala-D-Ala), a unit of peptidoglycan, is a rep
Externí odkaz:
https://doaj.org/article/c0463095cdcb4387a8bae6225ba11f39
Autor:
Motoyoshi Noike, Yusuke Ono, Yuji Araki, Ryo Tanio, Yusuke Higuchi, Hajime Nitta, Yoshimitsu Hamano, Tomonobu Toyomasu, Takeshi Sassa, Nobuo Kato, Tohru Dairi
Publikováno v:
PLoS ONE, Vol 7, Iss 8, p e42090 (2012)
Many clinically useful pharmaceuticals are semi-synthesized from natural products produced by actinobacteria and fungi. The synthetic protocols usually contain many complicated reaction steps and thereby result in low yields and high costs. It is the
Externí odkaz:
https://doaj.org/article/df1cc149159240dfa4e787f5d52cfc83
Autor:
Wanlu Xiao, Takeshi Tsunoda, Chitose Maruyama, Yoshimitsu Hamano, Yasushi Ogasawara, Tohru Dairi
Publikováno v:
Bioscience, Biotechnology & Biochemistry; Nov2023, Vol. 87 Issue 11, p1316-1322, 7p
Autor:
Tohru Dairi
Publikováno v:
Bioscience, Biotechnology & Biochemistry; Aug2023, Vol. 87 Issue 8, p797-808, 12p
Publikováno v:
Journal of antibiotics. 74:825-829
Menaquinone is an essential cofactor in the electron-transfer pathway for bacteria. Menaquinone is biosynthesized from chorismate using either the well-known canonical pathway established by pioneering studies in model microorganisms or the futalosin
Autor:
Tsung-Lin Li, Yung-Lin Wang, Chin-Yuan Chang, Ning-Shian Hsu, I-Wen Lo, Kuan-Hung Lin, Chun-Liang Chen, Chi-Fon Chang, Zhe-Chong Wang, Yasushi Ogasawara, Tohru Dairi, Chitose Maruyama, Yoshimitsu Hamano
Oxidized cysteine residues are highly reactive and may form covalent conjugates with other residues in proteins to enable proper functionalities, for example, the lysine-cysteine NOS bridge identified recently as an allosteric redox switch. To our kn
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::efa4c29d8cbe991835f2e15ea58e892c
https://doi.org/10.21203/rs.3.rs-2120064/v1
https://doi.org/10.21203/rs.3.rs-2120064/v1
Publikováno v:
ChemBioChem. 23
Salinipeptins belong to the type-A linaridin class of ribosomally synthesized and post-translationally modified peptides (RiPPs) comprising 22 amino acid residues with multiple D-amino acids. Although chirality of other type-A linaridins, such as gri