Zobrazeno 1 - 10
of 209
pro vyhledávání: '"Tohru, Sugimoto"'
Publikováno v:
Biophysics and Physicobiology, Vol 16 (2019)
5-Hydroxytryptamine (5-HT; serotonin) regulates metabolism and various homeostatic mechanisms in the body, and is involved in depression. These complicated functions of 5-HT are supported by several 5-HT receptor and 5-HT transporter subtypes. The de
Externí odkaz:
https://doaj.org/article/e25246492d344e1bafd1d12493018e61
Autor:
Tohru Sugimoto, Hajime Hosoi, Hiroshi Kuroda, Tomoko Iehara, Kunihiko Tsuchiya, Osamu Otabe, Ken Kikuchi, Shinichi Tamura, Yasumichi Kuwahara, Yoshiki Katsumi
Purpose: Malignant rhabdoid tumor (MRT) is an early childhood cancer with poor prognosis. Trastuzumab, a humanized monoclonal antibody against human epidermal growth factor receptor-2 (HER-2), has been shown to be effective against breast cancer and
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::59b5ac0714754bfb82260c1cbf6f6ad6
https://doi.org/10.1158/1078-0432.c.6516867.v1
https://doi.org/10.1158/1078-0432.c.6516867.v1
Autor:
Hajime Hosoi, Tadashi Sawada, Tohru Sugimoto, Akiko Misawa-Furihata, Toshihiko Imamura, Kunihiko Tsuchiya, Shinichi Tamura, Ken Kikuchi, Satoko Tsubai-Shimizu, Yoshiki Katsumi, Mitsuru Miyachi, Tomoko Iehara, Takahiro Gotoh, Shigeki Yagyu
Supplementary figure S1 (Online Only) Real-time PCR amplification plot and dissociation curve of DCR2 methylation analysis. A, DCR2 methylation analysis in KP-N-RTBM1 cell line DNA.
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::8f2f4463a1059c986ebaf702c4d084fe
https://doi.org/10.1158/1078-0432.22439737.v1
https://doi.org/10.1158/1078-0432.22439737.v1
Autor:
Tohru Sugimoto, Hajime Hosoi, Hiroshi Kuroda, Tomoko Iehara, Kunihiko Tsuchiya, Osamu Otabe, Ken Kikuchi, Shinichi Tamura, Yasumichi Kuwahara, Yoshiki Katsumi
Supplementary Data from Trastuzumab Activates Allogeneic or Autologous Antibody-Dependent Cellular Cytotoxicity against Malignant Rhabdoid Tumor Cells and Interleukin-2 Augments the Cytotoxicity
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::d916afb61f78aa7ba8cfe8c34b85a0ce
https://doi.org/10.1158/1078-0432.22439397.v1
https://doi.org/10.1158/1078-0432.22439397.v1
Autor:
Hajime Hosoi, Tadashi Sawada, Tohru Sugimoto, Akiko Misawa-Furihata, Toshihiko Imamura, Kunihiko Tsuchiya, Shinichi Tamura, Ken Kikuchi, Satoko Tsubai-Shimizu, Yoshiki Katsumi, Mitsuru Miyachi, Tomoko Iehara, Takahiro Gotoh, Shigeki Yagyu
Supplementary table 1 (Online Only) Primer sets used for DCR2 methylation analysis.
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::26504024026a8861b3aa3cfa923a5c06
https://doi.org/10.1158/1078-0432.22439731
https://doi.org/10.1158/1078-0432.22439731
Autor:
Hajime Hosoi, Tadashi Sawada, Tohru Sugimoto, Akiko Misawa-Furihata, Toshihiko Imamura, Kunihiko Tsuchiya, Shinichi Tamura, Ken Kikuchi, Satoko Tsubai-Shimizu, Yoshiki Katsumi, Mitsuru Miyachi, Tomoko Iehara, Takahiro Gotoh, Shigeki Yagyu
Background:MYCN amplification (MNA) in neuroblastoma is a strong indicator of poor prognosis. However, some MYCN nonamplified (non-MNA) cases show poor outcomes, and examining the status of the gene requires an operation, which may have surgical comp
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::257313664602064d8d421266f4c93f79
https://doi.org/10.1158/1078-0432.c.6517159
https://doi.org/10.1158/1078-0432.c.6517159
Autor:
Johji Inazawa, Issei Imoto, Misao Ohki, Fumie Hosoda, Tohru Sugimoto, Hajime Hosoi, Yuriko Sugino, Jun Inoue, Akiko Misawa
To identify genes whose expression patterns are altered by methylation of DNA, we established a method for scanning human genomes for methylated DNA sequences, namely bacterial artificial chromosome array-based methylated CpG island amplification (BA
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::9363c41bfc1a4fb1fbb1c9fe96f1d462
https://doi.org/10.1158/0008-5472.c.6494318.v1
https://doi.org/10.1158/0008-5472.c.6494318.v1
Autor:
Shigeki Yagyu, Tomoko Iehara, Shiro Tanaka, Takahiro Gotoh, Akiko Misawa-Furihata, Tohru Sugimoto, Wendy B London, Michael D Hogarty, Satoshi Teramukai, Akira Nakagawara, Eiso Hiyama, John M Maris, Hajime Hosoi
Publikováno v:
PLoS ONE, Vol 11, Iss 8, p e0161039 (2016)
We previously developed a method for determining MYCN gene amplification status using cell-free DNA fragments released from cancer cells into the blood of patients with neuroblastoma (NB). Here, we analyzed the relationship between MYCN amplification
Externí odkaz:
https://doaj.org/article/623bd94eed5241259ab578803041b063
Autor:
Hiroyuki Shimada, Robyn Lukeis, Junming Fang, Shahab Asgharzadeh, Araz Marachelian, Ryosuke Matsuno, Tohru Sugimoto, Toby Trahair, John M. Maris, Naohiko Ikegaki, Mikako Warren, Andrew J. Gifford
Publikováno v:
Pediatr Dev Pathol
Background Although MYCN (aka N-myc) amplification is reported in ∼20% of neuroblastomas, MYC (aka C-myc) amplification appears to be a rare event in this disease. As of today, only 2 MYC-amplified neuroblastomas have been briefly mentioned in the
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::6d473dabcfdf3b90731b693944755b00
https://doi.org/10.1177/1093526617749670
https://doi.org/10.1177/1093526617749670
Autor:
Jun Inoue, Akiko Misawa, Yukichi Tanaka, Shizuko Ichinose, Yuriko Sugino, Hajime Hosoi, Tohru Sugimoto, Issei Imoto, Johji Inazawa
Publikováno v:
PLoS ONE, Vol 4, Iss 9, p e7099 (2009)
BACKGROUND:Neuroblastoma (NB) is the most frequently occurring solid tumor in children, and shows heterogeneous clinical behavior. Favorable tumors, which are usually detected by mass screening based on increased levels of catecholamines in urine, re
Externí odkaz:
https://doaj.org/article/41c51cb0042a46898110c0993fac9bab