Zobrazeno 1 - 10
of 141
pro vyhledávání: '"Tohru, Ohnuma"'
Autor:
Tohru Ohnuma, Keizo Ishii
Publikováno v:
Cogent Engineering, Vol 6, Iss 1 (2019)
The Fukushima Daiichi Nuclear Power Plant accident caused by the tsunami following the Great East Japan Earthquake in March 2011 resulted in contamination in Namie and Iitate, located in Fukushima Prefecture. These villages are in mountainous areas w
Externí odkaz:
https://doaj.org/article/c9415d093dd34bd3ba19c7375a35059b
Autor:
Ayako Suzuki, Nobuto Shibata, Koji Kasanuki, Tomoyuki Nagata, Shunichiro Shinagawa, Nobuyuki Kobayashi, Tohru Ohnuma, Yoshihide Takeshita, Eri Kawai, Toshiki Takayama, Kenya Nishioka, Yumiko Motoi, Nobutaka Hattori, Kazuhiko Nakayama, Hisashi Yamada, Heii Arai
Publikováno v:
Dementia and Geriatric Cognitive Disorders Extra, Vol 6, Iss 1, Pp 90-97 (2016)
Background/Aims: Mutations in the presenilin 2 (PSEN2) gene cause familial Alzheimer's disease (AD). Common polymorphisms affect gene activity and increase the risk of AD. Nonsynonymous polymorphisms in the PSEN2 gene showed Lewy body dementia (LBD)
Externí odkaz:
https://doaj.org/article/6442245d32674aca9f0f80089e02ac8a
Autor:
Takanobu Nakazawa, Ryota Hashimoto, Kazuto Sakoori, Yuki Sugaya, Asami Tanimura, Yuki Hashimotodani, Kazutaka Ohi, Hidenaga Yamamori, Yuka Yasuda, Satomi Umeda-Yano, Yuji Kiyama, Kohtarou Konno, Takeshi Inoue, Kazumasa Yokoyama, Takafumi Inoue, Shusuke Numata, Tohru Ohnuma, Nakao Iwata, Norio Ozaki, Hitoshi Hashimoto, Masahiko Watanabe, Toshiya Manabe, Tadashi Yamamoto, Masatoshi Takeda, Masanobu Kano
Publikováno v:
Nature Communications, Vol 7, Iss 1, Pp 1-17 (2016)
The molecular mechanisms of neurotrophin receptor trafficking are only partially understood. Here the authors show that ARHGAP33 interacts with SORT1 to regulate TrkB trafficking, the dysfunction of which impairs synapse development and leads to schi
Externí odkaz:
https://doaj.org/article/76c7f59a209646a0ada889e8e6621f22
Publikováno v:
Frontiers in Psychiatry, Vol 9 (2018)
This literature review primarily aims to summarize our research, comprising both cross-sectional and longitudinal studies, and discuss the possibility of using microinflammation-related biomarkers as peripheral biomarkers in the diagnosis and monitor
Externí odkaz:
https://doaj.org/article/0969150a27f44d4ca0988b788e67a5f3
Autor:
Tohru Ohnuma, Keizo Ishii
Publikováno v:
Cogent Engineering, Vol 5, Iss 1 (2018)
The accident at the Fukushima Daiichi Nuclear Power Plant caused widespread contamination in Fukushima Prefecture. The area was mainly contaminated with radioisotopes of iodine 131, cesium 134, and cesium 137. The surface soil has been removed in an
Externí odkaz:
https://doaj.org/article/625f3ef328044d64adbd2ad75fba4945
Autor:
Tomoyuki Nagata, Nobuyuki Kobayashi, Jumpei Ishii, Shunichiro Shinagawa, Ritsuko Nakayama, Nobuto Shibata, Bolati Kuerban, Tohru Ohnuma, Kazuhiro Kondo, Heii Arai, Hisashi Yamada, Kazuhiko Nakayama
Publikováno v:
Dementia and Geriatric Cognitive Disorders Extra, Vol 5, Iss 1, Pp 64-73 (2015)
Background/Aims: In the present study, we examined whether DNA methylation of the brain-derived neurotrophic factor (BDNF) promoter is associated with the manifestation and clinical presentation of Alzheimer's disease (AD). Methods: Of 20 patients wi
Externí odkaz:
https://doaj.org/article/bcba0903cbb54d52b808c08d8579e73d
Autor:
Tohru Ohnuma, Keizo Ishii
Publikováno v:
Cogent Engineering, Vol 4, Iss 1 (2017)
More than 22,000,000 m3 of soil was contaminated with cesium (Cs) radioisotopes following the accident at the Fukushima Daiichi Nuclear Power Plant. For site remediation, it is necessary to reduce this huge volume of contaminated soil. To achieve thi
Externí odkaz:
https://doaj.org/article/2e3918e672ea44f6961f55440d477ace
Autor:
Tomoyuki Nagata, Nobuto Shibata, Shunichiro Shinagawa, Ritsuko Nakayama, Bolati Kuerban, Tohru Ohnuma, Heii Arai, Kazuhiko Nakayama, Hisashi Yamada
Publikováno v:
Dementia and Geriatric Cognitive Disorders Extra, Vol 3, Iss 1, Pp 272-280 (2013)
Background: Some polymorphisms of the neurotrophin family have previously been investigated as candidate genes for Alzheimer's disease (AD). In the present study, we examined whether neurotrophin-3 (NTF-3) polymorphisms are genetic risk factors in pa
Externí odkaz:
https://doaj.org/article/c67bb0cf6aab44a39790874fd91665f5
Autor:
Nobuto Shibata, Yumiko Motoi, Hiroyuki Tomiyama, Tohru Ohnuma, Bolati Kuerban, Katrin Tomson, Miwa Komatsu, Hiromi Shimazaki, Nobutaka Hattori, Heii Arai
Publikováno v:
Dementia and Geriatric Cognitive Disorders Extra, Vol 3, Iss 1, Pp 161-167 (2013)
Background and Aims: Similar clinical and pathological features have been observed in Alzheimer's disease (AD) and Parkinson's disease with dementia (PDD). Both the peroxisome proliferator-activated receptor-γ (PPAR-γ) gene and the peroxisome proli
Externí odkaz:
https://doaj.org/article/86ac6a0fd3ca4cfc8e44828b19a1d94d
Autor:
Tomoyuki Nagata, Shunichiro Shinagawa, Bolati Kuerban, Nobuto Shibata, Tohru Ohnuma, Heii Arai, Kazuhiko Nakayama, Hisashi Yamada
Publikováno v:
Dementia and Geriatric Cognitive Disorders Extra, Vol 3, Iss 1, Pp 66-73 (2013)
Aims: In the present study, we investigated whether apolipoprotein E (APOE) polymorphisms influenced the cognitive function of Japanese patients with Alzheimer's disease (AD) at certain ages. Methods: Among 200 outpatients with dementia and amnestic
Externí odkaz:
https://doaj.org/article/cc7c9b77da48438d8027de5ca5f8d7a3