Zobrazeno 1 - 10 of 147 pro vyhledávání: '"Tohru, Ohmori"'
1
Akademický článek
Comparative Efficacy and Safety of Immunotherapeutic Regimens with PD-1/PD-L1 Inhibitors for Previously Untreated Extensive-Stage Small Cell Lung Cancer: A Systematic Review and Network Meta-Analysis
Autor: Koichi Ando, Ryo Manabe, Yasunari Kishino, Sojiro Kusumoto, Toshimitsu Yamaoka, Akihiko Tanaka, Tohru Ohmori, Tsukasa Ohnishi, Hironori Sagara
Publikováno v: Current Oncology, Vol 28, Iss 2, Pp 1094-1113 (2021)
Improving therapeutic strategies for extensive-stage small cell lung cancer (ES-SCLC) remains a challenge. To date, no reports have directly compared the efficacy and safety of immune checkpoint inhibitors plus platinum–etoposide (ICIs+EP) with pla
Externí odkaz: https://doaj.org/article/5bd50b60997243feb6a4db0bd33e6a4d
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2
Akademický článek
Diverse Mechanisms of Resistance against Osimertinib, a Third-Generation EGFR-TKI, in Lung Adenocarcinoma Cells with an EGFR-Activating Mutation
Autor: Shigetoshi Nishihara, Toshimitsu Yamaoka, Fumihiro Ishikawa, Tohru Ohmori, Koichi Ando, Sojiro Kusumoto, Yasunari Kishino, Ryo Manabe, Yuki Hasebe, Hironori Sagara, Hitoshi Yoshida, Junji Tsurutani
Publikováno v: Cells, Vol 11, Iss 14, p 2201 (2022)
Osimertinib, a third-generation epidermal growth factor receptor (EGFR) tyrosine kinase inhibitor (TKI), is used as a first-line treatment for patients with EGFR-mutant non-small cell lung cancer (NSCLC). However, the mechanisms underlying its antica
Externí odkaz: https://doaj.org/article/cafd1222792e4fe19b6a94a44c4791b0
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3
Akademický článek
Up-regulation of Syndecan-4 contributes to TGF-β1-induced epithelial to mesenchymal transition in lung adenocarcinoma A549 cells
Autor: Yoko Toba-Ichihashi, Toshimitsu Yamaoka, Tohru Ohmori, Motoi Ohba
Publikováno v: Biochemistry and Biophysics Reports, Vol 5, Iss C, Pp 1-7 (2016)
Syndecan-4 (SDC4) is a cell-surface proteoglycan associated with cell adhesion, motility, and intracellular signaling. Here, we present that SDC4 functions as a positive regulator of the transforming growth factor (TGF)-β1-induced epithelial to mese
Externí odkaz: https://doaj.org/article/fc78142e05d94075b28869f886027c8c
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7
Data from Distinct Afatinib Resistance Mechanisms Identified in Lung Adenocarcinoma Harboring an EGFR Mutation
Autor: Yasutsuna Sasaki, Tsukasa Ohnishi, Hiroo Ishida, Koichi Ando, Sojiro Kusumoto, Yasunori Murata, Satoru Arata, Motoi Ohba, Tohru Ohmori, Toshimitsu Yamaoka
EGFR tyrosine kinase inhibitors (TKI) are associated with significant responses in non–small cell lung cancer (NSCLC) patients harboring EGFR-activating mutations. However, acquired resistance to reversible EGFR-TKIs remains a major obstacle. In pa
Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_________::2b6f966fe8afa66c6947b1ace9a96968
https://doi.org/10.1158/1541-7786.c.6541369
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