Zobrazeno 1 - 10
of 133
pro vyhledávání: '"Tohru, Itoh"'
Publikováno v:
Scientific Reports, Vol 14, Iss 1, Pp 1-9 (2024)
Abstract Chronic liver injury induces fibrosis that often proceeds to cirrhosis and hepatocellular carcinoma, indicating that prevention and/or resolution of fibrosis is a promising therapeutic target. Hepatic stellate cells (HSCs) are the major driv
Externí odkaz:
https://doaj.org/article/5dfc9d6cb6644a27a78fe1b6b36ad4c8
Autor:
Nobutaka Takeda, Atsunori Tsuchiya, Masaki Mito, Kazuki Natsui, Yui Natusi, Yohei Koseki, Kei Tomiyoshi, Fusako Yamazaki, Yuki Yoshida, Hiroyuki Abe, Masayuki Sano, Taketomo Kido, Yusuke Yoshioka, Junichi Kikuta, Tohru Itoh, Ken Nishimura, Masaru Ishii, Takahiro Ochiya, Atsushi Miyajima, Shuji Terai
Publikováno v:
Inflammation and Regeneration, Vol 43, Iss 1, Pp 1-14 (2023)
Abstract Background The progression of liver fibrosis leads to portal hypertension and liver dysfunction. However, no antifibrotic agents have been approved for cirrhosis to date, making them an unmet medical need. Small extracellular vesicles (sEVs)
Externí odkaz:
https://doaj.org/article/33ffc1abeeee43bea1671cd58272c823
Autor:
Yasuhiro Nakano, Sachie Nakao, Minako Sueoka, Daigo Kasahara, Yuri Tanno, Hideaki Sumiyoshi, Tohru Itoh, Atsushi Miyajima, Katsuto Hozumi, Yutaka Inagaki
Publikováno v:
Communications Biology, Vol 5, Iss 1, Pp 1-10 (2022)
Dll4/Notch1 signal promotes the progression of HCC, while Jag1/Notch2 signal antagonistically suppresses it in murine chemical hepatocarcinogenesis. Nakano et al. report that two distinct Notch signals regulate the progression of hepatocellular carci
Externí odkaz:
https://doaj.org/article/b8d8d5deaba64e4cbc50de2a16ed8551
Autor:
Shinichi Kinami, Naohiko Nakamura, Tomoharu Miyashita, Hidekazu Kitakata, Sachio Fushida, Takashi Fujimura, Tohru Itoh, Hiroyuki Takamura
Publikováno v:
BMC Cancer, Vol 21, Iss 1, Pp 1-10 (2021)
Abstract Background The correlation between tumor location and lymphatic flow distribution in gastric cancer has been previously reported, and PTD (Proximal – Transitional – Distal) classification was proposed. Our group updated and developed the
Externí odkaz:
https://doaj.org/article/2d2e637ae4f24f4896f2e8dcc76453f8
Autor:
Tohru Itoh
Publikováno v:
Cell Regeneration, Vol 10, Iss 1, Pp 1-4 (2021)
Externí odkaz:
https://doaj.org/article/6ee15719a3ce480f85d165ea23220106
Autor:
Naoki Tanimizu, Norihisa Ichinohe, Yasushi Sasaki, Tohru Itoh, Ryo Sudo, Tomoko Yamaguchi, Takeshi Katsuda, Takafumi Ninomiya, Takashi Tokino, Takahiro Ochiya, Atsushi Miyajima, Toshihiro Mitaka
Publikováno v:
Nature Communications, Vol 12, Iss 1, Pp 1-12 (2021)
Combining mouse hepatocyte progenitors and cholangiocytes ex vivo, the authors form an organoid that can drain bile ex vivo and transport metabolites, as in the liver.
Externí odkaz:
https://doaj.org/article/5ae34e70df8044cf9ed9cd6e6564d196
Autor:
Suguru Takeuchi, Atsunori Tsuchiya, Takahiro Iwasawa, Shunsuke Nojiri, Takayuki Watanabe, Masahiro Ogawa, Tomoaki Yoshida, Katsunori Fujiki, Yuta Koui, Taketomo Kido, Yusuke Yoshioka, Mayu Fujita, Junichi Kikuta, Tohru Itoh, Masaaki Takamura, Katsuhiko Shirahige, Masaru Ishii, Takahiro Ochiya, Atsushi Miyajima, Shuji Terai
Publikováno v:
npj Regenerative Medicine, Vol 6, Iss 1, Pp 1-14 (2021)
Abstract Mesenchymal stromal cells (MSCs) are used for ameliorating liver fibrosis and aiding liver regeneration after cirrhosis; Here, we analyzed the therapeutic potential of small extracellular vesicles (sEVs) derived from interferon-γ (IFN-γ) p
Externí odkaz:
https://doaj.org/article/ade7176a775045be931db93405b53155
Autor:
Norio Miyamura, Shoji Hata, Tohru Itoh, Minoru Tanaka, Miki Nishio, Michiko Itoh, Yoshihiro Ogawa, Shuji Terai, Isao Sakaida, Akira Suzuki, Atsushi Miyajima, Hiroshi Nishina
Publikováno v:
Nature Communications, Vol 8, Iss 1, Pp 1-10 (2017)
Senescent and injured cells affect tissue functions and can drive tumorigenesis. Thus, efficient elimination of these cells is pivotal for tissue integrity. Here Miyamuraet al. show that YAP acts as a cellular stress sensor and promotes the eliminati
Externí odkaz:
https://doaj.org/article/8b7ca4029c1c488caa7b2fb3bdb9af8f
Autor:
Hidekazu Kitakata, Tohru Itoh, Shinichi Kinami, Ken Kawaura, Kazu Hamada, Sadafumi Azukisawa, Rika Kobayashi, Junji Kamai, Takeo Kosaka
Publikováno v:
Endoscopy International Open, Vol 07, Iss 01, Pp E36-E42 (2019)
Background and study aims Endoscopic full-thickness resection (EFTR) is a useful procedure that allows minimal resection of the gastric wall because the tumor can be located endoscopically. However, the procedure carries a risk of peritoneal infectio
Externí odkaz:
https://doaj.org/article/cb24d285a86d48adb9534455129e8070
Autor:
Rika Kobayasi, Yuta Igarashi, Taishi Ishisaka, Sadahumi Azukisawa, Toshihiro Higashikawa, Tarou Himeno, Junji Kamai, Masashi Okuro, Kunimitsu Iwai, Takuro Morita, Tazuo Okuno, Kumie Kodera, Hiroshi Yano, Osamu Iritani, Tohru Itoh, Munetaka Matoba, Hidekazu Kitakata, Kazu Hamada, Hiroaki Kuno, Shigeto Morimoto, Ken Kawaura
Publikováno v:
World Journal of Oncology
A 77-year-old man who underwent radiotherapy for hepatocellular carcinoma 6 months prior consulted for esophageal obstruction. Esophagogastroduodenoscopy revealed an esophageal ulcer caused by radiotherapy for hepatocellular carcinoma. He was treated
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::cbf476c783968afa68cb2d4f4d7864ee
http://europepmc.org/articles/PMC8139740
http://europepmc.org/articles/PMC8139740