Zobrazeno 1 - 10
of 239
pro vyhledávání: '"Tohru, Abe"'
Autor:
Daijiro Ueda, Natsu Matsuda, Yuka Takaba, Nami Hirai, Mao Inoue, Taichi Kameya, Tohru Abe, Nao Tagaya, Yasuhiro Isogai, Yoshito Kakihara, Florian Bartels, Mathias Christmann, Tetsuro Shinada, Kaori Yasuda, Tsutomu Sato
Publikováno v:
Scientific Reports, Vol 14, Iss 1, Pp 1-10 (2024)
Abstract Onoceroids are a rare family of triterpenes. One representative onoceroid is ambrein, which is the main component of ambergris used as a traditional medicine. We have previously identified the onoceroid synthase, BmeTC, in Bacillus megateriu
Externí odkaz:
https://doaj.org/article/7ee4f5dccd7e47bfb8340e08c6b08ab7
Autor:
Tsutomu Takeuchi, Nobuyuki Miyasaka, Takashi Inui, Toshiro Yano, Toru Yoshinari, Tohru Abe, Takao Koike
Publikováno v:
Arthritis Research & Therapy, Vol 19, Iss 1, Pp 1-11 (2017)
Abstract Background Although both rheumatoid factor (RF) and anticyclic citrullinated peptide antibodies (anti-CCP) are useful for diagnosing rheumatoid arthritis (RA), the impact of these autoantibodies on the efficacy of tumor necrosis factor (TNF)
Externí odkaz:
https://doaj.org/article/03209e4a4150436186284aa8ff8451c0
Autor:
Tohru Abe, Mariko Hakamata, Akihito Nishiyama, Yoshitaka Tateishi, Sohkichi Matsumoto, Hisashi Hemmi, Daijiro Ueda, Tsutomu Sato
Publikováno v:
The FEBS Journal. 289:4981-4997
Isoprenoids with reduced Z,E-mixed prenyl groups are found in various organisms. To date, only polyprenol reductases (PR-Dol) involved in dolichol biosynthesis have been identified as enzymes capable of reducing Z,E-mixed prenyl groups. Although C
Autor:
null Tohru Abe, null Mariko Hakamata, null Akihito Nishiyama, null Yoshitaka Tateishi, null Sohkichi Matsumoto, null Hisashi Hemmi, null Daijiro Ueda, null Tsutomu Sato
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::c0de32fe2997edd380708341b66ccbd6
https://doi.org/10.1111/febs.16412/v2/response1
https://doi.org/10.1111/febs.16412/v2/response1
Publikováno v:
Chembiochem : a European journal of chemical biology. 21(20)
Comprehensive functional analyses of E-isoprenyl diphosphate synthases (E-IDSs) from nonpathogenic Mycobacterium vanbaalenii have been performed. Mv0992 and Mv1577 represent a nonaprenyl diphosphate (E-C45 ) synthase and a geranylgeranyl diphosphate
Autor:
Akihito Nishiyama, Makoto Matsumoto, Tohru Abe, Sohkichi Matsumoto, Kimiko Itoh, Yoshitaka Tateishi, Shaban A. Kaboso, Tsutomu Sato, Ryuki Kitamoto, Xiuhao Chen, Kentaro Kaneko, Yusuke Inoue, Mikayo Hayashi, Mayuko Osada-Oka, Yoshikazu Kawano, Mamoru Fujiwara, Yukiko Nishiuchi, Masanori Kawasaki
Publikováno v:
Antimicrob Agents Chemother
Delamanid (DLM), a nitro-dihydroimidazooxazole derivative currently approved for pulmonary multidrug-resistant tuberculosis (TB) therapy, is a prodrug activated by mycobacterial 7,8-didemethyl-8-hydroxy 5-deazaflavin electron transfer coenzyme (F(420
Publikováno v:
Tetrahedron. 71:7614-7619
Synthesis of aryl phosphinates was achieved through cross-coupling reactions of aryl iodides with H -phosphinates catalyzed by nickel under mild conditions. The method was applicable to various aryl iodides and H -phosphinates having defined stereoch
Autor:
Takao Koike, Toru Yoshinari, Nobuyuki Miyasaka, Toshiro Yano, Tohru Abe, Tsutomu Takeuchi, Takashi Inui
Publikováno v:
The Journal of Rheumatology. 42:599-607
Objective.To investigate the probability of clinical remission (REM) or low disease activity (LDA) after 1 year of infliximab (IFX) therapy based on disease activity at 3 months in patients with rheumatoid arthritis (RA).Methods.Methotrexate-refracto
Autor:
Takashi Inui, Tohru Abe, Nobuyuki Miyasaka, Takao Koike, Toru Yoshinari, Toshiro Yano, Tsutomu Takeuchi
Publikováno v:
Arthritis Research & Therapy
Arthritis Research & Therapy, Vol 19, Iss 1, Pp 1-11 (2017)
Arthritis Research & Therapy, Vol 19, Iss 1, Pp 1-11 (2017)
Background Although both rheumatoid factor (RF) and anticyclic citrullinated peptide antibodies (anti-CCP) are useful for diagnosing rheumatoid arthritis (RA), the impact of these autoantibodies on the efficacy of tumor necrosis factor (TNF) inhibito
Autor:
Tohru Abe, Hitoshi Kohsaka, Masaki Hiraoka, Tsukasa Matsubara, Seizo Yamana, Shoichi Ozaki, Tsutomu Takeuchi, Nobuyuki Miyasaka, Hirobumi Kondo, Shigeto Tohma, Ami Yamamoto, Hiroshi Hashimoto
Publikováno v:
Modern Rheumatology. 23:634-645
The primary objective of this study was to evaluate the tolerability of single and multiple doses of abatacept in Japanese patients with rheumatoid arthritis. Secondary objectives included evaluating its pharmacokinetics, pharmacodynamics, immunogeni