Zobrazeno 1 - 10
of 14
pro vyhledávání: '"Tohoru Tatsuhara"'
Quantitative Determinations of Phenobarbital and Carbamazepine in Serum by Nephelometric Immunoassay
Publikováno v:
Japanese Journal of Hospital Pharmacy. 19:464-470
An automated rate nephelometric assay (Beckman Array 360 System) for phenobarbital (PB) and carbamazepine (CBZ) was evaluated. The assay offers measuring ranges of 5-120μg/ml serum for PB and 2-40μg/ml for CBZ. The coefficients of variation for wit
Autor:
Tateo Sugimoto, Tohoru Tatsuhara, Hideki Muro, Kiyotaka Murakami, Yukiharu Yamaguchi, Naoki Nishida, Man Woo
Publikováno v:
Journal of chromatography. B, Biomedical applications. 663(1)
A modified method for the determination of valproylcarnitine in urine samples of patients receiving sodium valproate by gas chromatography—mass spectrometry with selected-ion monitoring is described. The chemically analogous internal standard 2-eth
Publikováno v:
Journal of chromatography. 526(2)
A simple method for the determination of nimustine hydrochloride in blood and brain by high-performance liquid chromatography was developed. A pH 4.52 buffer was used in the extraction from blood and a pH 5.0 buffer was used for brain. A pre-packed E
Autor:
Takashi Amisaki, Tohoru Tatsuhara
Publikováno v:
Journal of Pharmacobio-Dynamics. 11:335-348
There has been a considerable increase in popularity of the NONMEM method as a technique for estimating population pharmacokinetic parameters. The authors present another approach to population pharmacokinetic analysis, the alternative two stage meth
Publikováno v:
Journal of Chromatography A. 399:183-195
A modified method for the determination of valproic acid, its eleven metabolites and their conjugates in small samples of serum and urine by gas chromatography—mass spectrometry with selected-ion monitoring was developed. Valproic acid and its elev
Publikováno v:
Japanese Journal of Hospital Pharmacy. 13:20-23
Publikováno v:
Chemical and Pharmaceutical Bulletin. 30:1347-1351
A rapid and precise method for the determination of sulfite ion by isotachophoresis was developed. The leading electrolyte used was 0.01 M L-histidine hydrochloride in 30% aqueous acetone (pH 4.0) and the terminating electrolyte was 0.01 M hexanoic a
Autor:
T. Morita, Tohoru Tatsuhara, Yoshihiro Matsuda, Kenzo Takeshita, Hideki Muro, Takashi Amisaki
Publikováno v:
Rinsho yakuri/Japanese Journal of Clinical Pharmacology and Therapeutics. 19:749-757
The kinetics and metabolic disposition of valproic acid following a single oral administration of two preparations of sodium valproate (sustained-release tablets, KW-6066 N ;and standard tablets, Depakene) were investigated by a Latin square cross-ov
Autor:
Tohoru Tatsuhara, Fumie Tabuchi
Publikováno v:
Chemical and Pharmaceutical Bulletin. 28:779-782
An analytical method for meclofenoxate and its degradation products was established by high performance liquid chromatography. The chromatographic conditions were as follows : column, μ-bondapak C18 ; mobile phase, MeOH-0.1% ammonium carbonate of pH
Biochemical Behavior of the Depolymerized Product of Chondroitin Sulfate C by Ultrasonic Irradiation
Autor:
Tohoru Tatsuhara, Sadao Iguchi
Publikováno v:
Chemical and Pharmaceutical Bulletin. 21:2557-2561
Ultrasonically irradiated aqueous solution of chondroitin sulfate C was fractionated by the gel filtration method using Sephadex G 200, and the content of glucuronic acid in each fraction was measured. Only one new peak arose from the depolymerized p