Zobrazeno 1 - 10
of 123
pro vyhledávání: '"Todd W.B. Gehr"'
Publikováno v:
Cellular Physiology and Biochemistry, Vol 55, Iss S4, Pp 13-34 (2021)
Externí odkaz:
https://doaj.org/article/ff653f97e70946d1a4700cb1983e558b
The activation of nucleotide-binding oligomerization domain-like receptor containing pyrin domain 3 (NLRP3) inflammasome has been reported to importantly contribute to glomerular inflammation and injury under different pathological conditions such as
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::2174414b61db8061e9ef815d7796d2f1
https://doi.org/10.21203/rs.3.rs-2299466/v1
https://doi.org/10.21203/rs.3.rs-2299466/v1
Publikováno v:
Cellular Physiology and Biochemistry, Vol 55, Iss S4, Pp 13-34 (2021)
Cellular physiology and biochemistry : international journal of experimental cellular physiology, biochemistry, and pharmacology
Cellular physiology and biochemistry : international journal of experimental cellular physiology, biochemistry, and pharmacology
Podocytes play a vital role in the pathogenesis of nephrotic syndrome (NS), which is clinically characterized by heavy proteinuria, hypoalbuminemia, hyperlipidemia, and peripheral edema. The pathogenesis of NS has evolved through several hypotheses r
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::d54bb45c8ea40ac17200ba81d1aa5c83
https://www.cellphysiolbiochem.com/Articles/000356/
https://www.cellphysiolbiochem.com/Articles/000356/
Autor:
Joseph K. Ritter, Owais M. Bhat, Cristin D. W. Kaspar, Sarah Camus, Pin-Lan Li, Todd W.B. Gehr, Jason M. Kidd, Sara K. Dempsey, Erich Gulbins, Guangbi Li
Publikováno v:
The American Journal of Pathology. 190:1211-1223
Lysosomal acid ceramidase (Ac) has been shown to be critical for ceramide hydrolysis and regulation of lysosome function and cellular homeostasis. In the present study, we generated a knockout mouse strain (Asah1fl/fl/PodoCre) with a podocyte-specifi
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::4d4b013246c3a8bccb4c9cd594c11c87
https://doi.org/10.1016/j.ajpath.2020.02.008
https://doi.org/10.1016/j.ajpath.2020.02.008
Autor:
Jing Wang, Daniel E. Carl, Salvatore Carbone, Graham T. Gipson, Dave L. Dixon, Shobha Ghosh, Ion S. Jovin, Todd W.B. Gehr
Publikováno v:
Kidney International Reports, Vol 5, Iss 2, Pp 199-210 (2020)
Kidney International Reports
Kidney International Reports
Introduction Although chronic kidney disease (CKD) is associated with increased risk for coronary artery disease (CAD), the underlying mechanisms are not completely defined. In the present study, we tested the hypothesis that flux of cholesterol from
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::2315608dbffbb7cc3a4387d50e9ab9fa
https://doi.org/10.1016/j.ekir.2019.11.003
https://doi.org/10.1016/j.ekir.2019.11.003
Publikováno v:
Family Medicine ISBN: 9781493907793
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::7fc793017e4aecf7285171a18a129870
https://doi.org/10.1007/978-1-4939-0779-3_104-2
https://doi.org/10.1007/978-1-4939-0779-3_104-2
Publikováno v:
Heart Failure Clinics. 13:503-512
Diuretics are the most commonly prescribed class of drugs in patients with heart failure, and in the short term they remain the most effective treatment for relief from fluid congestion. This article reviews the mode of action of the various diuretic
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::1c32aae979d3c28a71b210f702b2c36c
https://doi.org/10.1016/j.hfc.2017.02.006
https://doi.org/10.1016/j.hfc.2017.02.006
Autor:
Layla Kamal, Julie A. Patterson, Rodney Stiltner, Andrea Ferreira-Gonzalez, Irfan Moinuddin, Dhiren Kumar, Richard K. Sterling, Trevor Reichman, Amit Sharma, Todd W.B. Gehr, Chandra Bhati, Ayana Andrews‐Joseph, Gaurav Gupta, Adrian Cotterell, Mary Baldecchi, Anam Alam, Nathaniel W. Brigle, Le Kang, Idris Yakubu, Yiran Zhang, Pamela Kimball, Marlon F. Levy, Anne L. King, Aamir Khan
Publikováno v:
American journal of transplantation : official journal of the American Society of Transplantation and the American Society of Transplant SurgeonsREFERENCES. 20(3)
We conducted an adaptive design single-center pilot trial between October 2017 and November 2018 to determine the safety and efficacy of ultra-short-term perioperative pangenotypic direct acting antiviral (DAA) prophylaxis for deceased hepatitis C vi
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::c46b39e4857c80d865d919636155a782
https://pubmed.ncbi.nlm.nih.gov/32701370
https://pubmed.ncbi.nlm.nih.gov/32701370
Autor:
Owais M. Bhat, Justin L. Poklis, Guangbi Li, Aolin Zhang, Todd W.B. Gehr, Yao Zou, Dandan Huang, Pin-Lan Li, Jason M. Kidd
Publikováno v:
Biochimica et biophysica acta. Molecular and cell biology of lipids
Podocytopathy and associated nephrotic syndrome (NS) have been reported in a knockout mouse strain (Asah1fl/fl/PodoCre) with a podocyte-specific deletion of α subunit (the main catalytic subunit) of acid ceramidase (Ac). However, the pathogenesis of
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::d769f4e62a5fb73df85db38c0b1e0777
https://doi.org/10.1016/j.bbalip.2020.158856
https://doi.org/10.1016/j.bbalip.2020.158856
Autor:
Laurence H. Beck, Salima Sadruddin, Rivka Ayalon, Dhiren Kumar, H. Davis Massey, Anne L. King, Hasan Fattah, Gaurav Gupta, Pamela Kimball, Jason M. Kidd, Luis F. Quintana, Todd W.B. Gehr
Publikováno v:
Clinical Transplantation. 30:461-469
Previous studies that have assessed the association of pre-transplant antiphospholipase A2 receptor autoantibody (PLA2R-Ab) concentration with a recurrence of membranous nephropathy (rMN) post-kidney transplant have yielded variable results. We teste
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::2f70cb7cae01819a6e04546ff1bb4fba
https://doi.org/10.1111/ctr.12711
https://doi.org/10.1111/ctr.12711